Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rebecca M Christoff"'
Autor:
Emily RR Mackie, Andrew S Barrow, Rebecca M Christoff, Belinda M Abbott, Anthony R Gendall, Tatiana P Soares da Costa
Publikováno v:
eLife, Vol 11 (2022)
Herbicides with novel modes of action are urgently needed to safeguard global agricultural industries against the damaging effects of herbicide-resistant weeds. We recently developed the first herbicidal inhibitors of lysine biosynthesis, which provi
Externí odkaz:
https://doaj.org/article/cbc58527ee934f6ab656dd0d1580b3ac
Autor:
Tatiana P Soares da Costa, Cody J Hall, Santosh Panjikar, Jessica A Wyllie, Rebecca M Christoff, Saadi Bayat, Mark D Hulett, Belinda M Abbott, Anthony R Gendall, Matthew A Perugini
Publikováno v:
eLife, Vol 10 (2021)
Weeds are becoming increasingly resistant to our current herbicides, posing a significant threat to agricultural production. Therefore, new herbicides with novel modes of action are urgently needed. In this study, we exploited a novel herbicide targe
Externí odkaz:
https://doaj.org/article/4a54238d54044027a2091d81d099209c
Author response: Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants
Autor:
Rebecca M. Christoff, Santosh Panjikar, Anthony R. Gendall, Jessica A Wyllie, Tatiana P. Soares da Costa, Matthew A. Perugini, Mark D. Hulett, Cody J Hall, Saadi Bayat, Belinda M. Abbott
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::931d7859e77a063e95fc7a1d31ab34a1
https://doi.org/10.7554/elife.69444.sa2
https://doi.org/10.7554/elife.69444.sa2
Autor:
Jessica A Wyllie, Rebecca M. Christoff, Belinda M. Abbott, Matthew A. Perugini, Cody J Hall, Santosh Panjikar, Anthony R. Gendall, Mark D. Hulett, Saadi Bayat, Tatiana P. Soares da Costa
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Weeds are becoming increasingly resistant to our current herbicides, posing a significant threat to agricultural production. Therefore, new herbicides with novel modes of action are urgently needed. In this study, we exploited a novel herbicide targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98dbcf7781d6074dda0891c75ff8745e
https://elifesciences.org/articles/69444
https://elifesciences.org/articles/69444
Autor:
Chamodi K. Gardhi, Tatiana P. Soares da Costa, Matthew A. Perugini, Belinda M. Abbott, Rebecca M. Christoff
Publikováno v:
MedChemComm. 10:1581-1588
Antibiotic resistance is only set to increase if significant action is not taken to combat the imminent threat of multidrug resistant pathogens. The development of inhibitors of the enzyme dihydrodipicolinate synthase (DHDPS), which is involved in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90f4f11912ab0456b429c5ad3f4b2f74
https://doi.org/10.1039/c9md00107g
https://doi.org/10.1039/c9md00107g
Autor:
Rebecca M. Christoff, Jessica K Holien, Belinda M. Abbott, Tatiana P. Soares da Costa, Saadi Bayat, Matthew A. Perugini
Publikováno v:
Bioorganic & Medicinal Chemistry. 52:116518
Dihydrodipicolinate synthase (DHDPS), responsible for the first committed step of the diaminopimelate pathway for lysine biosynthesis, has become an attractive target for the development of new antibacterial and herbicidal agents. Herein, we report t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::becdefbd60fb34a2e42ffa34e756fbd0
https://doi.org/10.1016/j.bmc.2021.116518
https://doi.org/10.1016/j.bmc.2021.116518
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:6267-6272
With multidrug resistant bacteria on the rise, novel antibiotics are becoming highly sought after. In 2008, eleven compounds were identified by high throughput screening as inhibitors of BasE, a key enzyme of the non-ribosomal peptide synthetase path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017ea73810d5d16e56fd8825456b1684
https://doi.org/10.1016/j.bmc.2017.08.015
https://doi.org/10.1016/j.bmc.2017.08.015
Autor:
Leslie W. Deady, Nathan J. O'Brien, Elliott D. Cope, Brendan S. Crabb, Belinda M. Abbott, Chamodi K. Gardhi, Greta E. Weiss, Melissa J. Buskes, Rebecca M. Christoff, Robabeh Kalhor, Paul R. Gilson, Boris Prinz, Dene R. Littler, Benjamin J. Richards, Katherine L. Harvey
Publikováno v:
Organic & Biomolecular Chemistry. 14:4617-4639
Central to malaria pathogenesis is the invasion of human red blood cells by Plasmodium falciparum parasites. Following each cycle of intracellular development and replication, parasites activate a cellular program to egress from their current host ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc507a46e38bcf23e43e61926e9a482e
https://doi.org/10.1039/c5ob02517f
https://doi.org/10.1039/c5ob02517f
Autor:
Chamodi K. Gardi, J. Mark Sutton, Belinda M. Abbott, Tatiana P. Soares da Costa, Matthew A. Perugini, Rebecca M. Christoff
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e774988ba944dd712721742724ad753
https://doi.org/10.1096/fasebj.2018.32.1_supplement.810.3
https://doi.org/10.1096/fasebj.2018.32.1_supplement.810.3