Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rebecca M, Broeckel"'
Autor:
Shelly J. Robertson, Olivia Bedard, Kristin L. McNally, Carl Shaia, Chad S. Clancy, Matthew Lewis, Rebecca M. Broeckel, Abhilash I. Chiramel, Jeffrey G. Shannon, Gail L. Sturdevant, Rebecca Rosenke, Sarah L. Anzick, Elvira Forte, Christoph Preuss, Candice N. Baker, Jeffrey M. Harder, Catherine Brunton, Steven Munger, Daniel P. Bruno, Justin B. Lack, Jacqueline M. Leung, Amirhossein Shamsaddini, Paul Gardina, Daniel E. Sturdevant, Jian Sun, Craig Martens, Steven M. Holland, Nadia A. Rosenthal, Sonja M. Best
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19) and is influenced by host genetics. To understand mechanisms of inflammation, animal mo
Externí odkaz:
https://doaj.org/article/4707d2cef54a462c9164528ec8d5861f
Autor:
Rebecca M Broeckel, Friederike Feldmann, Kristin L McNally, Abhilash I Chiramel, Gail L Sturdevant, Jacqueline M Leung, Patrick W Hanley, Jamie Lovaglio, Rebecca Rosenke, Dana P Scott, Greg Saturday, Fadila Bouamr, Angela L Rasmussen, Shelly J Robertson, Sonja M Best
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1009678 (2021)
Kyasanur Forest disease virus (KFDV) and the closely related Alkhurma hemorrhagic disease virus (AHFV) are emerging flaviviruses that cause severe viral hemorrhagic fevers in humans. Increasing geographical expansion and case numbers, particularly of
Externí odkaz:
https://doaj.org/article/e75b0f0e8a774ab2b7bf41f32357fe43
Autor:
Rebecca M. Broeckel, Nicole Haese, Takeshi Ando, Igor Dmitriev, Craig N. Kreklywich, John Powers, Michael Denton, Patricia Smith, Thomas E. Morrison, Mark Heise, Victor DeFilippis, Ilhem Messaoudi, David T. Curiel, Daniel N. Streblow
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Chikungunya virus (CHIKV) infections can cause severe and debilitating joint and muscular pain that can be long lasting. Current CHIKV vaccines under development rely on the generation of neutralizing antibodies for protection; however, the role of T
Externí odkaz:
https://doaj.org/article/e0f6d6c3c6d84f9c8c83a6a0453541c9
Autor:
Abhilash I. Chiramel, Nicholas R. Meyerson, Kristin L. McNally, Rebecca M. Broeckel, Vanessa R. Montoya, Omayra Méndez-Solís, Shelly J. Robertson, Gail L. Sturdevant, Kirk J. Lubick, Vinod Nair, Brian H. Youseff, Robin M. Ireland, Catharine M. Bosio, Kyusik Kim, Jeremy Luban, Vanessa M. Hirsch, R. Travis Taylor, Fadila Bouamr, Sara L. Sawyer, Sonja M. Best
Publikováno v:
Cell Reports, Vol 27, Iss 11, Pp 3269-3283.e6 (2019)
Summary: Tripartite motif-containing protein 5α (TRIM5α) is a cellular antiviral restriction factor that prevents early events in retrovirus replication. The activity of TRIM5α is thought to be limited to retroviruses as a result of highly specifi
Externí odkaz:
https://doaj.org/article/680b7a0b93c5469cbbde7dcdbb3d4d2d
Autor:
Maria Pelliccia, Patrizia Andreozzi, Jayson Paulose, Marco D’Alicarnasso, Valeria Cagno, Manuela Donalisio, Andrea Civra, Rebecca M. Broeckel, Nicole Haese, Paulo Jacob Silva, Randy P. Carney, Varpu Marjomäki, Daniel N. Streblow, David Lembo, Francesco Stellacci, Vincenzo Vitelli, Silke Krol
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
Keeping viral vaccines cold from the manufacturers to patients is problematic and costly. Here, Krol and others show additives that can significantly improve at very low concentrations the storage of adenovirus type 5 at ambient and elevated temperat
Externí odkaz:
https://doaj.org/article/6897222ac66a4957bef12c2b0a62fd79
Autor:
Stacey L. P. Scroggs, Danielle K. Offerdahl, Dylan P. Flather, Ciera N. Morris, Benjamin L. Kendall, Rebecca M. Broeckel, Paul A. Beare, Marshall E. Bloom
Publikováno v:
Viruses, Vol 13, Iss 1, p 8 (2020)
Repurposing FDA-approved drugs that treat respiratory infections caused by coronaviruses, such as SARS-CoV-2 and MERS-CoV, could quickly provide much needed antiviral therapies. In the current study, the potency and cellular toxicity of four fluoroqu
Externí odkaz:
https://doaj.org/article/c5dd3093812d4a3a933b84c689e76859
Autor:
Alec J Hirsch, Jessica L Smith, Nicole N Haese, Rebecca M Broeckel, Christopher J Parkins, Craig Kreklywich, Victor R DeFilippis, Michael Denton, Patricia P Smith, William B Messer, Lois M A Colgin, Rebecca M Ducore, Peta L Grigsby, Jon D Hennebold, Tonya Swanson, Alfred W Legasse, Michael K Axthelm, Rhonda MacAllister, Clayton A Wiley, Jay A Nelson, Daniel N Streblow
Publikováno v:
PLoS Pathogens, Vol 13, Iss 4, p e1006317 (2017)
[This corrects the article DOI: 10.1371/journal.ppat.1006219.].
Externí odkaz:
https://doaj.org/article/116ea9460e3f48fe8753fbc0acc79393
Autor:
Alec J Hirsch, Jessica L Smith, Nicole N Haese, Rebecca M Broeckel, Christopher J Parkins, Craig Kreklywich, Victor R DeFilippis, Michael Denton, Patricia P Smith, William B Messer, Lois M A Colgin, Rebecca M Ducore, Peta L Grigsby, Jon D Hennebold, Tonya Swanson, Alfred W Legasse, Michael K Axthelm, Rhonda MacAllister, Clayton A Wiley, Jay A Nelson, Daniel N Streblow
Publikováno v:
PLoS Pathogens, Vol 13, Iss 3, p e1006219 (2017)
Zika virus (ZIKV), an emerging flavivirus, has recently spread explosively through the Western hemisphere. In addition to symptoms including fever, rash, arthralgia, and conjunctivitis, ZIKV infection of pregnant women can cause microcephaly and othe
Externí odkaz:
https://doaj.org/article/55de2daddda341f08d68238e192dcd1f
Autor:
Shelly J, Robertson, Olivia, Bedard, Kristin L, McNally, Matthew, Lewis, Chad, Clancy, Carl, Shaia, Rebecca M, Broeckel, Abhilash I, Chiramel, Gail L, Sturdevant, Elvira, Forte, Christoph, Preuss, Candice N, Baker, Jeffrey, Harder, Catherine, Brunton, Steven, Munger, Daniel E, Sturdevant, Craig, Martens, Steven M, Holland, Nadia A, Rosenthal, Sonja M, Best
Publikováno v:
bioRxiv
Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19), with effective versus dysregulated responses influenced by host genetics. To understand mechani
Autor:
Dylan P Flather, Benjamin Luke Kendall, Paul A. Beare, Rebecca M. Broeckel, Marshall E. Bloom, Ciera N Morris, Danielle K. Offerdahl, Stacey L P Scroggs
Publikováno v:
Viruses, Vol 13, Iss 8, p 8 (2021)
Viruses
Volume 13
Issue 1
Viruses
Volume 13
Issue 1
Repurposing FDA-approved drugs that treat respiratory infections caused by coronaviruses, such as SARS-CoV-2 and MERS-CoV, could quickly provide much needed antiviral therapies. In the current study, the potency and cellular toxicity of four fluoroqu