Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Rebecca Lyn Carrier"'
Autor:
Yuan Li, An Qi Zhang, Abigail N. Koppes, Sanjin Hosic, Jessica Snyder, Ryan A. Koppes, Chia-Ming Wang, Joshua Luchan, Rebecca Lyn Carrier
Publikováno v:
Annals of Biomedical Engineering. 48:1916-1940
The barrier functions of the gastrointestinal tract rely in large part on a single layer of columnar intestinal epithelial cells. These epithelial cells are mediators of intestinal homeostasis, regulating and communicating biochemical signals between
Autor:
David T. Breault, Linda G. Griffith, Mario E. Gamboa, Victor Hernandez-Gordillo, Juan S. Gnecco, Rebecca Lyn Carrier, GiHun Choi, Arinola Lampejo, Alexander Brown, Timothy Kassis
Publikováno v:
PMC
Biomaterials
Biomaterials
Epithelial organoids derived from human donor tissues are important tools in fields ranging from regenerative medicine to drug discovery. Organoid culture requires expansion of stem/progenitor cells in Matrigel, a tumor-derived extracellular matrix (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39987c918b8a33776e3880f6f12cc61f
https://hdl.handle.net/1721.1/133521
https://hdl.handle.net/1721.1/133521
Autor:
Lampejo A, Timothy Kassis, Mario E. Gamboa, Linda G. Griffith, Juan S. Gnecco, David T. Breault, Rebecca Lyn Carrier, GiHun Choi, Hernandez-Gordillo
Epithelial organoids are now an important tool in fields ranging from regenerative medicine to drug discovery. Organoid culture requires Matrigel, a complex, tumor-derived, extracellular matrix. An alternative completely synthetic matrix could improv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e53edb6622af49f961fa18c69accac
Publikováno v:
Journal of Controlled Release. 240:544-560
The majority of newly discovered oral drugs are poorly water soluble, and co-administration with lipids has proven effective in significantly enhancing bioavailability of some compounds with low aqueous solubility. Yet, lipid-based delivery technolog
Publikováno v:
Acta Biomaterialia. 9:5201-5207
Mucus secretion from the body is ubiquitous, and finding materials that resist mucus adhesion is a major technological challenge. Here, using a high throughput platform with photo-induced graft polymerization, we first rapidly synthesized, screened a
Publikováno v:
Biotechnology and Bioengineering. 105:409-420
The ability to quantitatively predict the influence of a solubilization technology on oral absorption would be highly beneficial in rational selection of drug delivery technology and formulation design. Cyclodextrins (CDs) are cyclic oligosaccharides
Publikováno v:
Biotechnology and Bioengineering. 105:421-430
A model was developed for predicting the influence of cyclodextrins (CDs) delivered as a physical mixture with drug on oral absorption. CDs are cyclic oligosaccharides which form inclusion complexes with many drugs and are often used as solubilizing
Autor:
Murat Cirit, Jin Yu, Ujjal Sarkar, Rebecca Lyn Carrier, Emma M. Large, Linda G. Griffith, David Hughes, Kelly W. Chen, John S. Wishnok, Steven R. Tannenbaum
Publikováno v:
The FASEB Journal. 29
Autor:
Murat Cirit, Steven R. Tannenbaum, Rachelle Prantil-Baun, Jiajie Yu, David Hughes, Emma M. Large, Mark J. Mescher, Douglas A. Lauffenburger, Rebecca Lyn Carrier, Amanda R. Lever, John S. Wishnok, Ujjal Sarkar, Jonathan R. Coppeta, Kelly W. Chen, Linda G. Griffith, Cynthia L. Stokes, Nicholas A. Cilfone
Publikováno v:
The FASEB Journal. 29
Autor:
Tatyana Chernenko, Fulden Buyukozturk, Miloš Miljković, Mansoor M. Amiji, Max Diem, Rebecca Lyn Carrier
Active targeted delivery of nanoparticle-encapsulated agents to tumor cells in vivo is expected to enhance therapeutic effect with significantly less non-specific toxicity. Active targeting is based on surface modification of nanoparticles with ligan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a00dacfec4f8b7eb6b43d9a0f77ef20
https://europepmc.org/articles/PMC3843494/
https://europepmc.org/articles/PMC3843494/