Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rebecca L. Weir"'
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1435 (2021)
Stearoyl-CoA desaturase-1 (SCD1 or delta-9 desaturase, D9D) is a key metabolic protein that modulates cellular inflammation and stress, but overactivity of SCD1 is associated with diseases, including cancer and metabolic syndrome. This transmembrane
Externí odkaz:
https://doaj.org/article/d5331881b07e4e9e923e6ffba0052160
Autor:
Hui He, Rebecca L Weir, Jordan J Toutounchian, Jayaprakash Pagadala, Jena J Steinle, Jerome Baudry, Duane D Miller, Charles R Yates
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0180808 (2017)
Retinal microaneurysms, an early disease manifestation of diabetic retinopathy, are associated with retinal endothelial cell (REC) death and macular edema. We previously demonstrated that a quinic acid (QA) analog, KZ-41, promoted REC survival by blu
Externí odkaz:
https://doaj.org/article/9269fe234af542b5aa18ddc12742acbd
Autor:
Patricia M. Herman, Nabeel Qureshi, Susan D. Arick, Maria O. Edelen, Ron D. Hays, Anthony Rodriguez, Rebecca L. Weir, Ian D. Coulter
Publikováno v:
The journal of pain, vol 24, iss 3
Among those with low back pain (LBP), individuals with chronic LBP (CLBP) face different treatment recommendations and incur the majority of suffering and costs. However, the way CLBP has been defined varies greatly. This study used a scoping review
Autor:
Charles R. Yates, Jayaprakash Pagadala, Rebecca L. Weir, Jena J. Steinle, Jerome Baudry, Duane D. Miller, Jordan J. Toutounchian, Hui He
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 8, p e0180808 (2017)
PLoS ONE, Vol 12, Iss 8, p e0180808 (2017)
Retinal microaneurysms, an early disease manifestation of diabetic retinopathy, are associated with retinal endothelial cell (REC) death and macular edema. We previously demonstrated that a quinic acid (QA) analog, KZ-41, promoted REC survival by blu
Autor:
Rebecca L. Weir, Jerome Baudry, Sally R. Ellingson, Wilfredo Evangelista, Jason B. Harris, Karan Kapoor, Jeremy C. Smith
Publikováno v:
Bioorganicmedicinal chemistry. 24(20)
This paper describes and illustrates the use of ensemble-based docking, i.e., using a collection of protein structures in docking calculations for hit discovery, the exploration of biochemical pathways and toxicity prediction of drug candidates. We d