Effects of early-life antibiotics on the developing infant gut microbiome and resistome: a randomized trial

Autor: Marta Reyman, Marlies A. van Houten, Rebecca L. Watson, Mei Ling J. N. Chu, Kayleigh Arp, Wouter J. de Waal, Irene Schiering, Frans B. Plötz, Rob J. L. Willems, Willem van Schaik, Elisabeth A. M. Sanders, Debby Bogaert

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

Here, in a randomized trial of 147 infants receiving distinct antibiotic regimens for early-onset neonatal sepsis, Reyman et al. characterize the gut microbiome and resistance profiles, finding differential effects of antibiotic combinations on micro

Externí odkaz: https://doaj.org/article/626b3bdca10047e98c3200e64c2e11c0

Author Correction: Impact of delivery mode-associated gut microbiota dynamics on health in the first year of life

Autor: Marta Reyman, Marlies A. van Houten, Debbie van Baarle, Astrid A. T. M. Bosch, Wing Ho Man, Mei Ling J. N. Chu, Kayleigh Arp, Rebecca L. Watson, Elisabeth A. M. Sanders, Susana Fuentes, Debby Bogaert

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Externí odkaz: https://doaj.org/article/63bd69f1ce3a4b2fac4358ae4cd9d75a

Early-life viral infections are associated with disadvantageous immune and microbiota profiles and recurrent respiratory infections

Autor: Wouter A A, de Steenhuijsen Piters, Rebecca L, Watson, Emma M, de Koff, Raiza, Hasrat, Kayleigh, Arp, Mei Ling J N, Chu, Pieter C M, de Groot, Marlies A, van Houten, Elisabeth A M, Sanders, Debby, Bogaert

Publikováno v: Nature microbiology. 7(2)

The respiratory tract is populated by a specialized microbial ecosystem, which is seeded during and directly following birth. Perturbed development of the respiratory microbial community in early-life has been associated with higher susceptibility to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ee2e1088b0e8563e70313eb0a29ee151
https://pubmed.ncbi.nlm.nih.gov/35091713

Impact of delivery mode-associated gut microbiota dynamics on health in the first year of life

Autor: Elisabeth A. M. Sanders, Marlies A. van Houten, Wing Ho Man, Debbie van Baarle, Mei Ling J N Chu, Kayleigh Arp, Rebecca L. Watson, Debby Bogaert, Marta Reyman, Susana Fuentes, Astrid A. T. M. Bosch

Publikováno v: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Reyman, M, van Houten, M A, van Baarle, D, Bosch, A A T M, Man, W H, Chu, M L J N, Arp, K, Watson, R L, Sanders, E A M, Fuentes, S & Bogaert, D 2019, ' Impact of delivery mode-associated gut microbiota dynamics on health in the first year of life ', Nature Communications, vol. 10, 4997 . https://doi.org/10.1038/s41467-019-13014-7

The early-life microbiome appears to be affected by mode of delivery, but this effect may depend on intrapartum antibiotic exposure. Here, we assess the effect of delivery mode on gut microbiota, independent of intrapartum antibiotics, by postponing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861d1e9d111d8ba93f8a54d768ebb276
http://europepmc.org/articles/PMC6825150

Cellular and humoral immunity in a wild mammal: Variation with agesex and association with overwinter survival

Autor: Rebecca L, Watson, Tom N, McNeilly, Kathryn A, Watt, Josephine M, Pemberton, Jill G, Pilkington, Martin, Waterfall, Phoebe R T, Hopper, Daniel, Cooney, Rose, Zamoyska, Daniel H, Nussey

Publikováno v: Ecology and Evolution

Immune defenses are expected to be crucial for survival under the considerable parasite pressures experienced by wild animals. However, our understanding of the association between immunity and fitness in nature remains limited due to both the comple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::74995c2db035262d6820e289b9f3c955
https://pubmed.ncbi.nlm.nih.gov/28035261