Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Rebecca L. McNaughton"'
Publikováno v:
Trends in Biotechnology. 34:665-678
Several recent micro- and nanotechnologies have provided novel methods for biological studies of adherent cells because the small features of these new biotools provide unique capabilities for accessing cells without the need for suspension or lysis.
Autor:
Wonmo Kang, Biqin Dong, Tammy L. McGuire, Fan Zhou, Rebecca L. McNaughton, Horacio D. Espinosa, S. Shiva P. Nathamgari, Cheng Sun, Juan P. Giraldo-Vela, John A. Kessler
Publikováno v:
Lab on a Chip. 15:4591-4597
Sphere forming assays are routinely used for in vitro propagation and differentiation of stem cells. Because the stem cell clusters can become heterogeneous and polyclonal, they must first be dissociated into a single cell suspension for further clon
Autor:
Changjin Huang, Abbas Haddadi, Ruiguo Yang, Vincent Lemaitre, Rebecca L. McNaughton, Horacio D. Espinosa
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany). 14(12)
Stably transfected cell lines are widely used in drug discovery and biological research to produce recombinant proteins. Generation of these cell lines requires the isolation of multiple clones, using time-consuming dilution methods, to evaluate the
Autor:
Fazel Yavari, Wonmo Kang, Majid Minary-Jolandan, Horacio D. Espinosa, Rebecca L. McNaughton, A. Safi
Publikováno v:
SLAS Technology. 19:100-109
This brief report describes a novel tool for microfluidic patterning of biomolecules and delivery of molecules into cells. The microdevice is based on integration of nanofountain probe (NFP) chips with packaging that creates a closed system and enabl
Autor:
Rebecca L. McNaughton, Fazel Yavari, Juan P. Giraldo-Vela, Majid Minary-Jolandan, Horacio D. Espinosa, A. Safi, Wonmo Kang, Victor Parpoil
Publikováno v:
Nano Letters. 13:2448-2457
The ability to precisely deliver molecules into single cells is of great interest to biotechnology researchers for advancing applications in therapeutics, diagnostics, and drug delivery toward the promise of personalized medicine. The use of bulk ele
Autor:
Brian M. Hoffman, Rebecca L. McNaughton, Michael Roemelt, Jia Min Chin, Richard R. Schrock, Frank Neese
Publikováno v:
Journal of the American Chemical Society. 132:8645-8656
The trigonally symmetric Mo(III) coordination compounds [HIPTN(3)N]MoL (L = N(2), CO, NH(3); [HIPTN(3)N]Mo = [(3,5-(2,4,6-i-Pr(3)C(6)H(2))(2)C(6)H(3)NCH(2)CH(2))(3)N]Mo) are low-spin d(3) (S = (1)/(2)) species that exhibit a doubly degenerate (2)E gr
Autor:
Nicholas S. Lees, Rebecca L. McNaughton, Brian M. Hoffman, Patrick L. Holland, Wilda Vargas Gregory
Publikováno v:
Journal of the American Chemical Society. 130:546-555
Molybdenum-dependent nitrogenase binds and reduces N2 at the [Fe7, Mo, S9, X, homocitrate] iron-molybdenum cofactor (FeMo-co). Kinetic and spectroscopic studies of nitrogenase variants indicate that a single Fe-S face is the most likely binding site.
Autor:
Gang Bao, Brian Wile, Wonmo Kang, Andrew Tsourkas, Rebecca L. McNaughton, Juan P. Giraldo-Vela, Xuemei Zhang, Horacio D. Espinosa
New techniques for single-cell analysis enable new discoveries in gene expression and systems biology. Time-dependent measurements on individual cells are necessary, yet the common single-cell analysis techniques used today require lysing the cell, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395f46b839d5e1ab258b7ddfadb3feaa
https://europepmc.org/articles/PMC6016387/
https://europepmc.org/articles/PMC6016387/
Autor:
Michael K. Johnson, Rangan Krishnan, Michael W. W. Adams, Rebecca L. McNaughton, Francis E. Jenney, Donald M. Kurtz, Michael D. Clay, Tran Chin Yang, Brian M. Hoffman
Publikováno v:
Journal of the American Chemical Society. 128:16566-16578
Superoxide reductase (SOR) and P450 enzymes contain similar [Fe(N)4(SCys)] active sites and, although they catalyze very different reactions, are proposed to involve analogous low-spin (hydro)peroxo-Fe(III) intermediates in their respective mechanism
Autor:
Rebecca L. McNaughton, S. Shiva P. Nathamgari, Tammy L. McGuire, Horacio D. Espinosa, Wonmo Kang, John A. Kessler, Juan P. Giraldo-Vela
New techniques to deliver of nucleic acids and other molecules for gene editing and gene expression profiling, which can be performed with minimal perturbation to cell growth or differentiation, are essential for advancing biological research. Studyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11216484fbaf684fe01e0e987d3e9426
https://europepmc.org/articles/PMC4251430/
https://europepmc.org/articles/PMC4251430/