Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rebecca L. Davis-Harrison"'
Autor:
Rebecca L. Davis-Harrison, Alastair J. Florence, Jeremy Hinds, Scott Alan Frank, Frederik J.S. Doerr, Lee J. Burns, Becky Lee
Publikováno v:
Pharmaceutical Research
Purpose Spray drying plays an important role in the pharmaceutical industry for product development of sensitive bio-pharmaceutical formulations. Process design, implementation and optimisation require in-depth knowledge of process-product interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aba2ea936af1ee53021fec75d7fa768
https://doi.org/10.1007/s11095-020-02942-5
https://doi.org/10.1007/s11095-020-02942-5
Autor:
James H. Morrissey, Chad M. Rienstra, Rebecca L. Davis-Harrison, Mark J. Arcario, Narjes Tavoosi, Y. Zenmei Ohkubo, Taras V. Pogorelov, Mary C. Clay, Emad Tajkhorshid
Publikováno v:
The Journal of Biological Chemistry
Many regulatory processes in biology involve reversible association of proteins with membranes. Clotting proteins bind to phosphatidylserine (PS) on cell surfaces, but a clear picture of this interaction has yet to emerge. We present a novel explanat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e823f1ee318376f2c507aeec31ed7fd0
https://doi.org/10.1074/jbc.m111.251769
https://doi.org/10.1074/jbc.m111.251769
Autor:
Rebecca L. Davis-Harrison, Stephen G. Sligar, Emad Tajkhorshid, James H. Morrissey, Chad M. Rienstra, Aleksandra Z. Kijac, Vincent S. Pureza, Y. Z. Ohkubo
Publikováno v:
Journal of Thrombosis and Haemostasis. 7:169-172
The clotting cascade requires the assembly of protease-cofactor complexes on membranes with exposed anionic phospholipids. Despite their importance, protein-membrane interactions in clotting remain relatively poorly understood. Calcium ions are known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5618df497720100960d542a1e65912dd
https://doi.org/10.1111/j.1538-7836.2009.03390.x
https://doi.org/10.1111/j.1538-7836.2009.03390.x
Autor:
James H. Morrissey, Vincent S. Pureza, Rebecca L. Davis-Harrison, Stephen G. Sligar, Emad Tajkhorshid, Y. Zenmei Ohkubo
Publikováno v:
Thrombosis Research. 122:S23-S26
Blood clotting reactions, such as those catalyzed by the tissue factor:factor VIIa complex (TF:FVIIa), assemble on membrane surfaces containing anionic phospholipids such as phosphatidylserine (PS). In fact, membrane binding is critical for the funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0efe3940c6fb80156e4b26ec5684817
https://doi.org/10.1016/s0049-3848(08)70014-8
https://doi.org/10.1016/s0049-3848(08)70014-8
Publikováno v:
Biochemistry. 46:1840-1850
T cell receptor recognition of peptide/MHC has been described as proceeding through a "two-step" process in which the TCR first contacts the MHC molecule prior to formation of the binding transition state using the germline-encoded CDR1 and CDR2 loop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ddd442e2df82dabcc6625e2f20f298
https://doi.org/10.1021/bi061702p
https://doi.org/10.1021/bi061702p
Autor:
John R. Clemens, Tiffany K. Baxter, Rebecca L. Davis-Harrison, Susan J. Gagnon, William E. Biddison, Richard V. Turner, Kathryn M. Armstrong, Marale Damirjian, Brian M. Baker, Oleg Y. Borbulevych
Publikováno v:
Journal of Molecular Biology. 353:556-573
T cell receptor (TCR) recognition of peptide takes place in the context of the major histocompatibility complex (MHC) molecule, which accounts for approximately two-thirds of the peptide/MHC buried surface. Using the class I MHC HLA-A2 and a large pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13115a5b1c895e01b0fddeca2c50fe4
https://doi.org/10.1016/j.jmb.2005.08.024
https://doi.org/10.1016/j.jmb.2005.08.024
Publikováno v:
Journal of Molecular Biology. 346:533-550
A6 and B7 are two alphabeta T cell receptors (TCRs) that recognize the Tax peptide presented by the class I major histocompatibility molecule HLA-A2 (Tax/HLA-A2). Despite the fact that the two TCRs have different CDR loops and use different amino aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6e13594897b87363669590452f4013
https://doi.org/10.1016/j.jmb.2004.11.063
https://doi.org/10.1016/j.jmb.2004.11.063
Autor:
Tiffany K. Baxter, Rebecca L. Davis-Harrison, John C. Beck, William E. Biddison, Susan J. Gagnon, Richard V. Turner, Anne-Kathrin Binz, Brian M. Baker
Publikováno v:
Journal of Biological Chemistry. 279:29175-29184
Mutational studies of T cell receptor (TCR) contact residues on the surface of the human class I major histocompatibility complex (MHC) molecule HLA-A2 have identified a "functional hot spot" that comprises Arg(65) and Lys(66) and is involved in reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dc6c66a7047788ea796cfb29b58298c
https://doi.org/10.1074/jbc.m403372200
https://doi.org/10.1074/jbc.m403372200
Autor:
Rebecca L. Davis-Harrison, Chad M. Rienstra, Stephanie A. Smith, Julie N. R. Collins, James H. Morrissey, Sharon H. Choi
Polyphosphates, linear polymers of inorganic phosphates linked by phosphoanhydride bonds, are widely present among organisms and play diverse roles in biology, including functioning as potent natural modulators of the human blood clotting system. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf9b1cadc29575b184dd277dc1bb09a
https://europepmc.org/articles/PMC2976836/
https://europepmc.org/articles/PMC2976836/
Publikováno v:
Blood. 120:1109-1109
Abstract 1109 Most steps in the blood coagulation cascade obligatorily take place on membrane surfaces and are dependent on the exposure of phosphatidylserine (PS). Many coagulation proteins bind to PS-containing membrane bilayers in a calcium-depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60ac72b547ac54113c51f6f03e4ba993
https://doi.org/10.1182/blood.v120.21.1109.1109
https://doi.org/10.1182/blood.v120.21.1109.1109