Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rebecca L. Dahlin"'
Autor:
Johnny Lam, Lucas A. Kinard, Antonios G. Mikos, Esther J. Lee, F. Kurtis Kasper, Rebecca L. Dahlin, Steven Lu
Publikováno v:
Acta Biomaterialia. 10:4574-4582
There exists a strong clinical need for a more capable and robust method to achieve bone augmentation, and a system with fine-tuned delivery of demineralized bone matrix (DBM) has the potential to meet that need. As such, the objective of the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6c146432134fb9db5d1f1aad9194cd
https://doi.org/10.1016/j.actbio.2014.07.011
https://doi.org/10.1016/j.actbio.2014.07.011
Publikováno v:
Tissue Engineering Part C: Methods. 20:514-523
In this work, we evaluated the ability of 3D co-cultures with mesenchymal stem cells (MSCs) to redifferentiate monolayer expanded articular chondrocytes (ACs) and produce cartilaginous extracellular matrix at varying stages of the dedifferentiation p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760d62b46d2129b9d6bf33ef1b52aaa5
https://doi.org/10.1089/ten.tec.2013.0532
https://doi.org/10.1089/ten.tec.2013.0532
Autor:
John A. Jansen, Ville V. Meretoja, Johnny Lam, Yasuhiko Tabata, Mark E. Wong, Antonios G. Mikos, Esther J. Lee, J.J.J.P van den Beucken, Jordan E. Trachtenberg, Rebecca L. Dahlin, Fred K Kasper, Steven Lu
Publikováno v:
Osteoarthritis and Cartilage, 22, 1291-300
Osteoarthritis and Cartilage, 22, 9, pp. 1291-300
Osteoarthritis and Cartilage, 22, 9, pp. 1291-300
Contains fulltext : 136446.pdf (Publisher’s version ) (Closed access) OBJECTIVE: To investigate the ability of cell-laden bilayered hydrogels encapsulating chondrogenically and osteogenically (OS) pre-differentiated mesenchymal stem cells (MSCs) to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007588bfdaf7ff8268012927c1d2a23e
https://hdl.handle.net/2066/136446
https://hdl.handle.net/2066/136446
Autor:
Antonios G. Mikos, John A. Jansen, Mark E. Wong, Yasuhiko Tabata, Lucas A. Kinard, Simon Young, Allan M. Henslee, F. Kurtis Kasper, Rebecca L. Dahlin, Patrick P. Spicer, Chia Ye Chu, Jeroen J.J.P. van den Beucken
Publikováno v:
Journal of Biomedical Materials Research Part A. 102:2079-2088
The objective of the present study was to develop a preclinical animal model for evaluating bone augmentation and to examine the level of bone augmentation induced by hydrogel composites. Design criteria outlined for the development of the animal mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c5a53fa6c71fd75828cccb5726adb8b
https://doi.org/10.1002/jbm.a.34878
https://doi.org/10.1002/jbm.a.34878
Publikováno v:
AIChE Journal. 59:3158-3166
The combination of reduced oxygen tension and flow perfusion bioreactor culture is investigated for its effect on the proliferation, glycosaminoglycan production, and chondrogenic gene expression of bovine articular chondrocytes on porous polymer sca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::872ffcae95e9cea57036e097bcb84cf3
https://doi.org/10.1002/aic.13958
https://doi.org/10.1002/aic.13958
Publikováno v:
Tissue Engineering Part B: Reviews. 17:349-364
Polymeric nanofibers can be produced using methods such as electrospinning, phase separation, and self-assembly, and the fiber composition, diameter, alignment, degradation, and mechanical properties can be tailored to the intended application. Nanof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d19fbded8cafce586ce1eff92c7eeb1
https://doi.org/10.1089/ten.teb.2011.0238
https://doi.org/10.1089/ten.teb.2011.0238
Autor:
Shantikumar V. Nair, Brendan M. Watson, Antonios G. Mikos, Binulal N. Sathy, Rebecca L. Dahlin, Lucas A. Kinard, Patrick P. Spicer
Publikováno v:
Tissue engineering. Part A. 21(19-20)
Our previous in vivo study showed that multilayered scaffolds made of an angiogenic layer embedded between an osteogenic layer and an osteoconductive layer, with layer thickness in the 100-400 μm range, resulted in through-the-thickness vascularizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2a6f47d29f0c7929e5f4f983facb47
https://pubmed.ncbi.nlm.nih.gov/26262560
https://pubmed.ncbi.nlm.nih.gov/26262560
Autor:
Johnny Lam, F. Kurtis Kasper, Clark J. Needham, Antonios G. Mikos, Rebecca L. Dahlin, Steven Lu, Lucas A. Kinard
This work investigated the ability of co-cultures of articular chondrocytes and mesenchymal stem cells (MSCs) to repair articular cartilage in osteochondral defects. Bovine articular chondrocytes and rat MSCs were seeded in isolation or in co-culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077e680d3a148bb503ab344c385a2bf2
https://europepmc.org/articles/PMC4109803/
https://europepmc.org/articles/PMC4109803/
This work investigated the effect of flow perfusion bioreactor culture with and without transforming growth factor-β3 (TGF-β3) supplementation on the proliferation, extracellular matrix (ECM) production, and chondrogenic gene expression of chondroc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50b8e7ffcdcba98ec2357b4cdc56006
https://europepmc.org/articles/PMC4229696/
https://europepmc.org/articles/PMC4229696/
Autor:
F. Kurtis Kasper, Sarita R. Shah, Johnny Lam, Rebecca L. Dahlin, Brendan M. Watson, Antonios G. Mikos, Lucas A. Kinard, Steven Lu, Clark J. Needham
Native osteochondral repair is often inadequate due to the inherent properties of the tissue and current clinical repair strategies can result in healing with a limited lifespan and donor site morbidity. This work investigates the use of polymeric ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931e4e11537ef667f9d5ac030a273a3e
https://europepmc.org/articles/PMC4160371/
https://europepmc.org/articles/PMC4160371/