Výsledky vyhledávání - "Rebecca L Smathers-McCullough"

Akademický článek

Short term feeding of a high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout mice.

Autor: Colin T Shearn, Kelly E Mercer, David J Orlicky, Leah Hennings, Rebecca L Smathers-McCullough, Bangyan L Stiles, Martin J J Ronis, Dennis R Petersen

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e96553 (2014)

Hepatospecific deletion of PTEN results in constitutive activation of Akt and increased lipogenesis. In mice, the addition of a high fat diet (HFD) downregulates lipogenesis. The aim of this study was to determine the effects of a HFD on hepatocellul

Externí odkaz: https://doaj.org/article/68d583e19f9d478cbaab11e66f0aad96

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Identification of 5′ AMP-activated Kinase as a Target of Reactive Aldehydes during Chronic Ingestion of High Concentrations of Ethanol*

Autor: David J. Orlicky, Rebecca L. Smathers-McCullough, Colin T. Shearn, Dennis R. Petersen, Donald S. Backos

The production of reactive aldehydes including 4-hydroxy-2-nonenal (4-HNE) is a key component of the pathogenesis in a spectrum of chronic inflammatory hepatic diseases including alcoholic liver disease (ALD). One consequence of ALD is increased oxid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bc686b06d0a1c84d5542ed9bf9be30
https://europepmc.org/articles/PMC4140901/

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Short term feeding of a high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout mice

Autor: Leah Hennings, David J. Orlicky, Martin J. J. Ronis, Rebecca L. Smathers-McCullough, Bangyan L. Stiles, Dennis R. Petersen, Kelly E. Mercer, Colin T. Shearn

Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 5, p e96553 (2014)

Background Hepatospecific deletion of PTEN results in constitutive activation of Akt and increased lipogenesis. In mice, the addition of a high fat diet (HFD) downregulates lipogenesis. The aim of this study was to determine the effects of a HFD on h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe011ac713c6319ea24e0d7874fa4bc
https://pubmed.ncbi.nlm.nih.gov/24818992

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