Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Rebecca L Sheets"'
Autor:
Cheng Cheng, Jason G D Gall, Wing-pui Kong, Rebecca L Sheets, Phillip L Gomez, C Richter King, Gary J Nabel
Publikováno v:
PLoS Pathogens, Vol 3, Iss 2, p e25 (2007)
Recombinant adenoviral (rAd) vectors elicit potent cellular and humoral immune responses and show promise as vaccines for HIV-1, Ebola virus, tuberculosis, malaria, and other infections. These vectors are now widely used and have been generally well
Externí odkaz:
https://doaj.org/article/2c43de1347124144b7c865b52c63b6fd
Autor:
Robert K. M. Choy, A. Louis Bourgeois, Christian F. Ockenhouse, Richard I. Walker, Rebecca L. Sheets, Jorge Flores
Publikováno v:
Clin Microbiol Rev
The timelines for developing vaccines against infectious diseases are lengthy, and often vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of protective efficacy. The application of controlled human challen
Publikováno v:
Emerging Microbes & Infections, 11(1):384-391
Emerging Microbes & Infections
article-version (VoR) Version of Record
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 384-391 (2022)
Emerging Microbes & Infections
article-version (VoR) Version of Record
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 384-391 (2022)
This paper presents the key outcomes of the above WHO informal consultation with global stakeholders including regulatory authorities, vaccine developers and manufacturers, academia and other international health organizations and institutions involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7f9459a5f34dc70d34c3cbe0fda451
https://repository.publisso.de/resource/frl:6431707
https://repository.publisso.de/resource/frl:6431707
Publikováno v:
Biologicals. 44:73-89
The clinical development of prophylactic HIV-1/AIDS vaccines is confounded by numerous scientific challenges and these in turn result in challenges to regulators reviewing clinical trial applications (CTAs). The search for an HIV-1/AIDS vaccine will
Autor:
Rebecca L. Sheets, Vijaya Rangavajhula, Jeffrey K. Pullen, Stuart Z. Shapiro, Vijay L. Mehra, Chris Butler, Michael Pensiero
Publikováno v:
Vaccine. 33:1757-1766
The Division of AIDS Vaccine Research Program funds the discovery and development of HIV/AIDS vaccine candidates. Basic researchers, having discovered a potential vaccine in the laboratory, next want to take that candidate into the clinic to test the
Publikováno v:
Biologicals. 42:223-236
Since the earliest days of biological product manufacture, there have been a number of instances where laboratory studies provided evidence for the presence of adventitious agents in a marketed product. Lessons learned from such events can be used to
Autor:
Nandini Sane, Paula Niksa, Jerald C. Sadoff, Alexander C. Schmidt, Stephen Karakasidis, Valerie B. Randolph, Phillip Minor, James Gombold, Kitti Neumann, Paul Duncan, James A. Richardson, Rebecca L. Sheets, Renita Johnson-Leva, John Podczasy
Publikováno v:
Vaccine. 32:2916-2926
Viral vaccines and the cell substrates used to manufacture them are subjected to tests for adventitious agents, including viruses, contaminate. Some of the compendial methods (in vivo and in vitro in cell culture) were established in the mid-20th cen
Autor:
Baevin Carbery, Michael Hendry, Robert T. Chen, Marc Gurwith, Lisa Mac, Richard C. Condit, Stephen J. Seligman, Jean-Louis Excler, Arifa S. Khan, Kenneth I. Berns, Rebecca L. Sheets, Louisa E. Chapman, Anna-Lise Williamson, Najwa Khuri-Bulos, Bettina Klug, James S. Robertson
Publikováno v:
Vaccine. 33(1):73-75
Recombinant viral vectors provide an effective means for heterologous antigen expression in vivo and thus represent promising platforms for developing novel vaccines against human pathogens from Ebola to tuberculosis. An increasing number of candidat
Autor:
Rebecca L. Sheets
Publikováno v:
Vaccine. 31:2791-2795
The manner in which viral vaccines are produced in a biological system makes them vulnerable to microbial contamination. Considerable effort is expended to avoid such contamination and to detect it if it occurred. Is this effort warranted, efficient,
Autor:
Richard C. Condit, James S. Robertson, Thomas P. Monath, Vidisha Singh, Marc Gurwith, Rebecca L. Sheets, Robert T. Chen, Denny Kim, Jean-Louis Excler, Lisa M. Mac, Stephen J. Seligman, R. Michael Hendry, Anna-Lise Williamson, Karin Bok
Publikováno v:
Vaccine
In 2003 and 2013, the World Health Organization convened informal consultations on characterization and quality aspects of vaccines based on live virus vectors. In the resulting reports, one of several issues raised for future study was the potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68953db033c55c79bf4f46ea6a02eac0
https://europepmc.org/articles/PMC5204448/
https://europepmc.org/articles/PMC5204448/