Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Rebecca L Ross"'
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Systemic sclerosis (SSc) is a terminal disease characterized by vasculopathy, tissue fibrosis, and autoimmunity. Although the exact etiology of SSc remains unknown, endothelial dysfunction, oxidative stress, and calcium handling dysregulation have be
Externí odkaz:
https://doaj.org/article/60184fa03e5e442cbd2e8ca07b86cc95
Autor:
Kulveer Mankia, Paul Emery, Lesley-Anne Bissell, Brendan Clarke, Darren Newton, Rebecca L Ross, Laurence Duquenne, Benazir Saleem, Aamir Aslam, Pam Hughes, Diane Corsadden, Clive Carter, Fatima A Nadat, Panji Mulipa, Mark Lobb, Katie Mbara, Ruth Morton, Sophie Dibb, Rahaymin Chowdhury, Alexandra Pike, Vishal Kakkar, Sinisia Savic, Francesco DelGaldo
Publikováno v:
RMD Open, Vol 8, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/5dde514756a244ce8e1b853f8feac6a2
Autor:
Rebecca L Ross, Julie E Burns, Claire F Taylor, Paul Mellor, Deborah H Anderson, Margaret A Knowles
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84411 (2013)
Bladder cancers commonly show genetic aberrations in the phosphatidylinositol 3-kinase signaling pathway. Here we have screened for mutations in PIK3R1, which encodes p85α, one of the regulatory subunits of PI3K. Two hundred and sixty-four bladder t
Externí odkaz:
https://doaj.org/article/70b90ef277df461b884b7d40bb5d48c5
Publikováno v:
Rheumatology. 62
Background/Aims Activation of Type I IFN response has been shown to be present in blood and tissue in systemic sclerosis (SSc) and correlates with disease pathogenesis and therapy response. It is currently unknown whether the tissue-specific Type I I
Autor:
Rebecca L Ross, Emily Clarke, Will Merchant, Ioanna Georgiou, Panji Mulipa, Antonio Carriero, Giuseppina Abignano, Ariane Herrick, Christopher Denton, Natalia Riobo-Del Galdo, Francesco Del Galdo
Publikováno v:
Rheumatology. 62
Background/Aims The VEDOSS study has recently indicated that more than 50% of patients affected by Raynaud’s phenomenon (RP) and specific SSc anti-nuclear antibodies (ANA) and/or nailfold videocapillaroscopy changes (NVC) (sRP) satisfied ACR/EULAR
Autor:
Christopher. W. Wasson, Eva. M. Clavane, Rebecca. L. Ross, Gemma Migneco, Cristina Antinozzi, Jane. M. Y. Brown, Luigi Di Luigi, Clive. S. McKimmie, Francesco Del Galdo, Paul. J. Meakin
BackgroundThe beta-amyloid precursor protein cleaving enzyme 1 (BACE1) is well known for its role in the development of Alzheimer’s disease via the generation of β-amyloid. Recent publications, including our own, have demonstrated a role for this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65c1f79584eb3b2ec24beeb008fbb637
https://doi.org/10.1101/2022.12.22.521579
https://doi.org/10.1101/2022.12.22.521579
Autor:
Benazir Saleem, Rebecca L Ross, Lesley-Anne Bissell, Aamir Aslam, Kulveer Mankia, Laurence Duquenne, Diane Corsadden, Clive Carter, Pam Hughes, Fatima A Nadat, Panji Mulipa, Mark Lobb, Brendan Clarke, Katie Mbara, Ruth Morton, Sophie Dibb, Rahaymin Chowdhury, Darren Newton, Alexandra Pike, Vishal Kakkar, Sinisia Savic, Francesco DelGaldo, Paul Emery
ObjectivesTo assess antibody and T cell responses to SARS-CoV-2 vaccination in patients with rheumatoid arthritis (RA) on disease-modifying antirheumatic drugs (DMARDs).MethodsThis prospective study recruited 100 patients with RA on a variety of DMAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85ddb47a7cd090612e6d5031adb8bdc
https://eprints.whiterose.ac.uk/186610/1/e002050.full.pdf
https://eprints.whiterose.ac.uk/186610/1/e002050.full.pdf
Autor:
Christopher W. Wasson, Jörg H W Distler, Clarissa Corinaldesi, Rebecca L. Ross, Agne Antanaviciute, Clive S. McKimmie, Francesco Del Galdo, Yasser M. El-Sherbiny, Steve Holmes, Antonio Carriero, Ian M. Carr, Gemma Migneco
Publikováno v:
Annals of the Rheumatic Diseases
ObjectivesPlasmacytoid dendritic cells (pDC) have been implicated in the pathogenesis of autoimmune diseases, such as scleroderma (SSc). However, this has been derived from indirect evidence using ex vivo human samples or mouse pDC in vivo. We have d
Publikováno v:
Rheumatology. 60:4395-4400
Objectives Tissue fibrosis in SSc is driven by active fibroblasts (myofibroblasts). Previous studies have shown the intracellular chloride channel 4 (CLIC4) mediates the activation of cancer-associated fibroblasts. In this study we investigated the r
Autor:
Francesco Del Galdo, Ioanna Ch. Georgiou, Rebecca G. Wells, Christopher W. Wasson, Rebecca L. Ross, Clarissa Corinaldesi, Natalia A. Riobo-Del Galdo
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-15 (2020)
Arthritis Research & Therapy
Arthritis Research & Therapy
ObjectivesSystemic sclerosis (SSc) is characterised by tissue fibrosis of the major organs of the body including the skin, lungs and heart. We have previously reported that the lncRNA HOTAIR plays a central role in the activation of SSc myofibroblast