Výsledky vyhledávání - "Rebecca L Barnes"

Akademický článek

Comparative genomics reveals two novel RNAi factors in Trypanosoma brucei and provides insight into the core machinery.

Autor: Rebecca L Barnes, Huafang Shi, Nikolay G Kolev, Christian Tschudi, Elisabetta Ullu

Publikováno v: PLoS Pathogens, Vol 8, Iss 5, p e1002678 (2012)

The introduction ten years ago of RNA interference (RNAi) as a tool for molecular exploration in Trypanosoma brucei has led to a surge in our understanding of the pathogenesis and biology of this human parasite. In particular, a genome-wide RNAi scre

Externí odkaz: https://doaj.org/article/2c76ab3c1b384ddcab99fb13a4f36f53

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A protein purification card game develops subject knowledge and transferable skills

Autor: Rebecca L. Barnes

Publikováno v: Journal of Biological Education. 56:365-375

Games can help learners of all ages retain knowledge and build skills such as critical thinking. As such, they could be a useful tool in supporting practical training at the university level. This ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae9bf2c6ad1d393ab32088ff56338a04
https://doi.org/10.1080/00219266.2020.1799844

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Student belonging: the impact of disability status within and between academic institutions

Autor: Hilda Mulrooney, Rebecca L. Barnes, Alison F. Kelly

Publikováno v: New Directions in the Teaching of Physical Sciences

Belonging at university is a complex and important issue which relates to student attainment but is more challenging for non-traditional students, including those with disability. This study, part of a larger project, explored differences in academic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3521c6ef65ba97205e89177a2f101c53
https://doi.org/10.29311/ndtps.v0i16.3607

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Targeting the Parasite's DNA with Methyltriazenyl Purine Analogs Is a Safe, Selective, and Efficacious Antitrypanosomal Strategy

Autor: Rebecca L. Barnes, Boris Rodenko, Harry P. de Koning, Reto Brun, Abdulsalam A. M. Alkhaldi, Richard McCulloch, Marcel Kaiser, Godwin U. Ebiloma, Martin J. Wanner, Gerrit-Jan Koomen

Publikováno v: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, 59(11), 6708-6716. American Society for Microbiology

The human and veterinary disease complex known as African trypanosomiasis continues to inflict significant global morbidity, mortality, and economic hardship. Drug resistance and toxic side effects of old drugs call for novel and unorthodox strategie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c1c5c391c253d2304cd367f49de00a
https://doi.org/10.1128/AAC.00596-15

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Role of the Trypanosoma brucei HEN1 Family Methyltransferase in Small Interfering RNA Modification

Autor: Rebecca L. Barnes, Christian Tschudi, Huafang Shi, Nicholas Carriero, Elisabetta Ullu, Vanessa D. Atayde

Publikováno v: Eukaryotic Cell. 13:77-86

Parasitic protozoa of the flagellate order Kinetoplastida represent one of the deepest branches of the eukaryotic tree. Among this group of organisms, the mechanism of RNA interference (RNAi) has been investigated in Trypanosoma brucei and to a lesse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9770e2da3d993a72dec4217b77b97504
https://doi.org/10.1128/ec.00233-13

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Trypanosoma cruzi MSH2: Functional analyses on different parasite strains provide evidences for a role on the oxidative stress response☆

Autor: Gustavo C. Lana, Eduardo de Figueiredo Peloso, Alice Machado-Silva, Fernanda Ramos Gadelha, Ying Chen, Carlos Renato Machado, Priscila C. Campos, Santuza M. R. Teixeira, Richard McCulloch, Danielle G. Passos-Silva, Wanderson D. DaRocha, Rebecca L. Barnes, Viviane Grazielle Silva, Marisa Helena Gennari de Medeiros, Carolina Furtado

Publikováno v: Molecular and Biochemical Parasitology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Graphical abstract T. cruzi II strains accumulate more 8-oxoguanine in the kDNA after hydrogen peroxide-induced 18 oxidative stress than T. cruzi I strains. NT: untreated; T: treated. Research highlights ▶ Distinct levels of DNA mismatch repair act

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1643f349c7756c23f445829fe9ca2f46
http://europepmc.org/articles/PMC3142612

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Trypanosoma brucei homologous recombination is dependent on substrate length and homology, though displays a differential dependence on mismatch repair as substrate length decreases

Autor: Richard McCulloch, Rebecca L. Barnes

Publikováno v: Nucleic Acids Research

Homologous recombination functions universally in the maintenance of genome stability through the repair of DNA breaks and in ensuring the completion of replication. In some organisms, homologous recombination can perform more specific functions. One

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75fc97e84c2739948d934330ccd31f3c
https://doi.org/10.1093/nar/gkm249

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Novel Copolymers of Styrene and Alkyl Ring‐Substituted 2‐Cyano‐N,N‐dimethyl‐3‐phenyl‐2‐propenamides

Autor: Jerry W. Curran, Whitney K. Castle, Rebecca L. Barnes, Mojgan B. Ghorbanpour, Farida Fatima, Hellene Demetzensky, Gregory B. Kharas, Selena M. Russel, Maria R. Fath, Hope Merideth, Xue Tian

Publikováno v: Journal of Macromolecular Science, Part A. 44:1-5

Electrophilic trisubstituted ethylene monomers, alkyl ring‐substituted 2‐cyano‐N,N‐dimethyl‐3‐phenyl‐2‐propenamides, RC6H4CH[dbnd]C(CN)CON(CH3)2 (where R is H, 2‐CH3, 3‐CH3, 4‐CH3, 4‐CH2CH3, 4‐CH(CH3)2, 4‐CH2CH2CH2CH3, 2,4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a151f7a35acfcf15fdf6e14dca77704
https://doi.org/10.1080/10601320601041761

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Comparative genomics reveals two novel RNAi factors in Trypanosoma brucei and provides insight into the core machinery

Autor: Nikolay G. Kolev, Rebecca L. Barnes, Elisabetta Ullu, Huafang Shi, Christian Tschudi

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 8, Iss 5, p e1002678 (2012)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880cde486ae74c54f4dd65ac09c97ac1
https://pubmed.ncbi.nlm.nih.gov/22654659

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The RNA Interference Pathway in Trypanosoma brucei

Autor: Nikolay G. Kolev, Elisabetta Ullu, Rebecca L. Barnes, Christian Tschudi

Publikováno v: RNA Metabolism in Trypanosomes ISBN: 9783642286865

In most eukaryotic cells, expression or delivery of long double-stranded RNA (dsRNA) signals the presence of foreign and/or potentially dangerous nucleic acids, such as viruses or transcripts derived from retroposons and transposons. As a consequence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::962f535766320a314863a0037950dd0a
https://doi.org/10.1007/978-3-642-28687-2_8

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