Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Rebecca L, Hull"'
Autor:
Sina A. Gharib, Rachna Vemireddy, Joseph J. Castillo, Brendy S. Fountaine, Theo K. Bammler, James W. MacDonald, Rebecca L. Hull-Meichle, Sakeneh Zraika
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Insulin secretion is impaired in individuals with cystic fibrosis (CF), contributing to high rates of CF-related diabetes (CFRD) and substantially increasing disease burden. To develop improved therapies for CFRD, better knowledge of pancrea
Externí odkaz:
https://doaj.org/article/02eecb3558cb4daeb1a5360a32a28b02
Autor:
Nadine Nagy, Kathryn S. Czepiel, Gernot Kaber, Darko Stefanovski, Aviv Hargil, Nina Pennetzdorfer, Robert Targ, Saranya C. Reghupaty, Thomas N. Wight, Robert B. Vernon, Rebecca L. Hull-Meichle, Payton Marshall, Carlos O. Medina, Hunter Martinez, Anissa Kalinowski, Rudolph D. Paladini, Stavros Garantziotis, Joshua W. Knowles, Paul L. Bollyky
Publikováno v:
Cells, Vol 13, Iss 20, p 1727 (2024)
Given that the extracellular matrix polymer hyaluronan (HA) has been implicated in longevity, we asked whether 4-methylumbelliferone (4-MU), an inhibitor of HA synthesis, impacts lifespan in mice. We designed a prospective study of long-term administ
Externí odkaz:
https://doaj.org/article/da7d8866843c4dd994d1c93481a81662
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Cystic fibrosis (CF) is a multi-organ disease caused by loss-of-function mutations in CFTR (which encodes the CF transmembrane conductance regulator ion channel). Cystic fibrosis related diabetes (CFRD) occurs in 40-50% of adults with CF and is assoc
Externí odkaz:
https://doaj.org/article/0b938453eae94ecda480ced02c4cc63f
Autor:
Nathalie Esser, Christine Schmidt, Breanne M. Barrow, Laura Cronic, Daryl J. Hackney, Stephen M. Mongovin, Meghan F. Hogan, Andrew T. Templin, Joseph J. Castillo, Rebecca L. Hull, Sakeneh Zraika
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Treatment of heart failure with the angiotensin receptor-neprilysin inhibitor sacubitril/valsartan improved glycemic control in individuals with type 2 diabetes. The relative contribution of neprilysin inhibition versus angiotensin II receptor antago
Externí odkaz:
https://doaj.org/article/2ca52c5595b6419c9d324310bf524e62
Autor:
Melissa S. Putman, Andrew W. Norris, Rebecca L. Hull, Michael R. Rickels, Lori Sussel, Scott M. Blackman, Christine L. Chan, Katie Larson Ode, Tanicia Daley, Arlene A. Stecenko, Antoinette Moran, Meagan J. Helmick, Sharon Cray, Jessica A. Alvarez, Virginia A. Stallings, Katherine L. Tuggle, John P. Clancy, Thomas L. Eggerman, John F. Engelhardt, Andrea Kelly
Publikováno v:
Diabetes. 72:677-689
Cystic fibrosis (CF) is a recessive disorder arising from mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein. CFTR is expressed in numerous tissues, with high expression in the airways, small and lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb55f5e1de29e45a35794f2f19379ee
https://doi.org/10.2337/db22-0949
https://doi.org/10.2337/db22-0949
Autor:
Joseph J. Castillo, Alfred C. Aplin, Daryl J. Hackney, Meghan F. Hogan, Nathalie Esser, Andrew T. Templin, Rehana Akter, Steven E. Kahn, Daniel P. Raleigh, Sakeneh Zraika, Rebecca L. Hull
Publikováno v:
Diabetologia
AIMS/HYPOTHESIS: The islet vasculature, including its constituent islet endothelial cells, is a key contributor to the microenvironment necessary for normal beta cell health and function. In type 2 diabetes, islet amyloid polypeptide (IAPP) aggregate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::543211b7d68db9bdfa5b08af41921348
https://doi.org/10.1007/s00125-022-05756-9
https://doi.org/10.1007/s00125-022-05756-9
Autor:
Teresa L. Mastracci, Minoti Apte, Laufey T. Amundadottir, Alexandra Alvarsson, Steven Artandi, Melena D. Bellin, Ernesto Bernal-Mizrachi, Alejandro Caicedo, Martha Campbell-Thompson, Zobeida Cruz-Monserrate, Abdelfattah El Ouaamari, Kyle J. Gaulton, Andrea Geisz, Mark O. Goodarzi, Manami Hara, Rebecca L. Hull-Meichle, Alexander Kleger, Alison P. Klein, Janel L. Kopp, Rohit N. Kulkarni, Mandar D. Muzumdar, Anjaparavanda P. Naren, Scott A. Oakes, Søren S. Olesen, Edward A. Phelps, Alvin C. Powers, Cherie L. Stabler, Temel Tirkes, David C. Whitcomb, Dhiraj Yadav, Jing Yong, Norann A. Zaghloul, Stephen J. Pandol, Maike Sander
Publikováno v:
Diabetes.
In the article cited above, the affiliations for authors Stephen J. Pandol and Maike Sander were inadvertently transposed. The correct affiliation for Stephen J. Pandol is Department of Gastroenterology, Cedars-Sinai Medical Center, Los Angeles, CA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc44c953819ad848ff947e0be7c5dc9a
https://doi.org/10.2337/db23-er08
https://doi.org/10.2337/db23-er08
Autor:
Nadine Nagy, Gernot Kaber, Vivekananda G. Sunkari, Payton L. Marshall, Aviv Hargil, Hedwich F. Kuipers, Heather D. Ishak, Marika Bogdani, Rebecca L. Hull, Maria Grandoch, Jens W. Fischer, Tracey L. McLaughlin, Thomas N. Wight, Paul L. Bollyky
Publikováno v:
bioRxiv
Pancreatic β-cell dysfunction and death are central to the pathogenesis of type 2 diabetes (T2D). We have identified a novel role for the inflammatory extracellular matrix polymer hyaluronan (HA) in this pathophysiology. Low levels of HA are present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae04a1e25ff819bcbbe00d44dc1bdc6d
https://doi.org/10.1101/2023.02.28.530522
https://doi.org/10.1101/2023.02.28.530522
Autor:
Nathalie, Esser, Stephen M, Mongovin, Jacqueline, Parilla, Breanne M, Barrow, Thomas O, Mundinger, Brendy S, Fountaine, Megan J, Larmore, Joseph J, Castillo, Rehana, Akter, Rebecca L, Hull, Sakeneh, Zraika
Publikováno v:
Am J Physiol Endocrinol Metab
Type 2 diabetes is associated with the upregulation of neprilysin, a peptidase capable of cleaving glucoregulatory peptides such as glucagon-like peptide-1 (GLP-1). In humans, use of the neprilysin inhibitor sacubitril in combination with an angioten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c8fb8c338ce71d519f28c580d56881f
https://pubmed.ncbi.nlm.nih.gov/35128957
https://pubmed.ncbi.nlm.nih.gov/35128957
Autor:
Nathalie Esser, Stephen M. Mongovin, Jacqueline Parilla, Breanne M. Barrow, Thomas O. Mundinger, Brendy S. Fountaine, Megan J. Larmore, Joseph J. Castillo, Rehana Akter, Rebecca L. Hull, Sakeneh Zraika
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 322:E307-E318
The neprilysin inhibitor, sacubitril, improves glycemic status in a mouse model of reduced insulin secretion. Sacubitril enhances intravenous but not oral glucose-mediated insulin secretion. The increased glucose-mediated insulin secretion is GLP-1 r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b7a38cdff715869db9c71f679e2e833
https://doi.org/10.1152/ajpendo.00234.2021
https://doi.org/10.1152/ajpendo.00234.2021