Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rebecca Kristina, Edwin"'
Autor:
Bandish Kapadia, Soma Behera, Sireesh T. Kumar, Tapan Shah, Rebecca Kristina Edwin, Phanithi Prakash Babu, Partha Chakrabarti, Kishore V.L. Parsa, Parimal Misra
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106120- (2023)
Summary: The physiological and metabolic functions of PIMT/TGS1, a third-generation transcriptional apparatus protein, in glucose homeostasis sustenance are unclear. Here, we observed that the expression of PIMT was upregulated in the livers of short
Externí odkaz:
https://doaj.org/article/7916694cb4b84c08b1d801d7d14c52a4
Autor:
Gangireddy Sujeevan, Reddy, Sharda, Shukla, Harshavardhan, Bhuktar, Kazi Amirul, Hossain, Rebecca Kristina, Edwin, Varadaraj Bhat, Giliyaru, Parimal, Misra, Manojit, Pal
Publikováno v:
RSC advances. 12(41)
In view of the reported chorismate mutase (CM or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::493934782820392cad99257141d947b9
https://pubmed.ncbi.nlm.nih.gov/36275143
https://pubmed.ncbi.nlm.nih.gov/36275143
Autor:
Sharda Shukla, R. Nishanth Rao, Harshavardhan Bhuktar, Rebecca Kristina Edwin, Trinath Jamma, Raghavender Medishetti, Sharmistha Banerjee, Varadaraj Bhat Giliyaru, Gautham G. Shenoy, Srinivas Oruganti, Parimal Misra, Manojit Pal
Publikováno v:
Bioorganic Chemistry. 134:106452
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a688efa011e5b48445763bf869f2aef1
https://doi.org/10.1016/j.bioorg.2023.106452
https://doi.org/10.1016/j.bioorg.2023.106452
Autor:
Rebecca Kristina Edwin, Nagalakshmi Challa, Rahul Sharma, K. Satyamoorthy, Kishore Parsa, Parimal Misra
Publikováno v:
Drug discovery today. 27(8)
Transcriptional coactivators play a crucial role in regulating gene expression. PRIP interacting protein with methyl transferase domain (PIMT)/trimethyl guanosine synthase 1 (TGS1) is a co-activator interacting protein with an RNA methyl transferase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49adb1345b061db19481bf338f397d2e
https://pubmed.ncbi.nlm.nih.gov/35462043
https://pubmed.ncbi.nlm.nih.gov/35462043
Autor:
Jetta Sandeep, Kumar, Gangireddy Sujeevan, Reddy, Raghavender, Medishetti, Kazi, Amirul Hossain, B, Thirupataiah, Jhansi, Edelli, Shilpak, Dilip Bele, Rebecca, Kristina Edwin, Alex, Joseph, Gautham G, Shenoy, C, Mallikarjuna Rao, Manojit, Pal
Publikováno v:
Bioorganic Chemistry. 124:105857
Addressing the increasing incidences of cancer worldwide along with the multifaceted problem of drug resistance via development of new anticancer agents has become an essential goal. Due to the known cytotoxic effects and reported Akt inhibitory pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a387ad6cbe4e19cbbdaec9295533147
https://doi.org/10.1016/j.bioorg.2022.105857
https://doi.org/10.1016/j.bioorg.2022.105857
Autor:
B. Thirupataiah, Gangireddy Sujeevan Reddy, C. Mallikarjuna Rao, Gautham G. Shenoy, Jetta Sandeep Kumar, Shilpak Dilip Bele, Nitesh Kumar, Rebecca Kristina Edwin, Alex Joseph, Raghavender Medishetti, Kazi Amirul Hossain, Aramita Ray, Manojit Pal
Publikováno v:
European journal of medicinal chemistry. 201
A new class of 3-substituted isocoumarin/3-alkylidenephthalide based novel small molecules derived from rosuvastatin were designed and synthesized via the ultrasound assisted Cu-mediated coupling-cyclization in a single pot with remarkable regioselec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a3f18e500bf1bcb9745ee86e110a31
https://pubmed.ncbi.nlm.nih.gov/32599323
https://pubmed.ncbi.nlm.nih.gov/32599323
Autor:
C. Mallikarjuna Rao, Manojit Pal, Gangireddy Sujeevan Reddy, B. Thirupataiah, Kazi Amirul Hossain, Aramita Ray, Alex Joseph, Rebecca Kristina Edwin, Jetta Sandeep Kumar, Parameswar Behera, Gautham G. Shenoy, Shilpak Dilip Bele, Raghavender Medishetti
Publikováno v:
Journal of Molecular Structure. 1240:130574
The Sonochemical synthesis of a library of 3-methyleneisoindolin-1-one based novel small molecules derived from rosuvastatin designed as potential anticancer agents was undertaken. A Cu-mediated coupling-cyclization strategy was employed to prepare t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7930d0012556e2daeb634b811ba20c83
https://doi.org/10.1016/j.molstruc.2021.130574
https://doi.org/10.1016/j.molstruc.2021.130574
Autor:
Manojit Pal, Raghu Chandrashekhar Hariharapura, Gautham G. Shenoy, Ampalam Venkata Snehalatha, Parimal Misra, Rebecca Kristina Edwin, Varadaraj Bhat Giliyaru, Gangireddy Sujeevan Reddy, Kazi Amirul Hossain
Publikováno v:
Bioorganic chemistry. 91
The chorismate mutase (CM) is considered as an attractive target for the identification of potential antitubercular agents due to its absence in animals but not in bacteria. A series of 3-indolylmethyl substituted pyrazolotriazinone derivatives were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4061aa21fb84bd56a5eb068402ed4059
https://pubmed.ncbi.nlm.nih.gov/31400552
https://pubmed.ncbi.nlm.nih.gov/31400552
Autor:
P.S.V.K. Sri Saranya, Rebecca Kristina Edwin, Gopalakrishnan Bulusu, Manjulatha Khanapur, Raj Kumar Patel, K. Shiva Kumar, Maddela Prabhakar, Parimal Misra, Mallika Alvala, Manojit Pal
Publikováno v:
Bioorganicmedicinal chemistry. 25(6)
Mycobacterium tuberculosis chorismate mutase (MtbCM) catalyzes the rearrangement of chorismate to prephenate in the shikimate biosynthetic pathway to form the essential amino acids, phenylalanine and tyrosine. Two genes encoding chorismate mutase hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b089bfd7d38d4a082ffe2c537fdf3ca
https://pubmed.ncbi.nlm.nih.gov/28202315
https://pubmed.ncbi.nlm.nih.gov/28202315