Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Rebecca Kesselring"'
Autor:
Jost Luenstedt, Fabian Hoping, Reinhild Feuerstein, Bernhard Mauerer, Christopher Berlin, Julian Rapp, Lisa Marx, Wilfried Reichardt, Dominik von Elverfeldt, Dietrich Alexander Ruess, Dorothea Plundrich, Claudia Laessle, Andreas Jud, Hannes Philipp Neeff, Philipp Anton Holzner, Stefan Fichtner-Feigl, Rebecca Kesselring
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundResection of colorectal liver metastasis is the standard of care for patients with Stage IV CRC. Despite undoubtedly improving the overall survival of patients, pHx for colorectal liver metastasis frequently leads to disease recurrence. The
Externí odkaz:
https://doaj.org/article/499172be44134767b086b72d003c9d06
Autor:
Ziwen Zheng, Thomas Wieder, Bernhard Mauerer, Luisa Schäfer, Rebecca Kesselring, Heidi Braumüller
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11673 (2023)
Therapeutic options for metastatic colorectal cancer (mCRC) are very limited, and the prognosis using combination therapy with a chemotherapeutic drug and a targeted agent, e.g., epidermal growth factor receptor or tyrosine kinase, remains poor. Ther
Externí odkaz:
https://doaj.org/article/7e645e3cfc2c472bb7a2a4f05389235e
Autor:
Heidi Braumüller, Bernhard Mauerer, Christopher Berlin, Dorothea Plundrich, Patrick Marbach, Pierre Cauchy, Claudia Laessle, Esther Biesel, Philipp Anton Holzner, Rebecca Kesselring
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
More than half of all patients with colorectal cancer (CRC) develop distant metastasis and, depending on the local stage of the primary tumor, up to 48% of patients present peritoneal carcinomatosis (PC). PC is often considered as a widespread metast
Externí odkaz:
https://doaj.org/article/0e63f9652dac4d72ae2d262af07c4fbb
Autor:
Heidi Braumüller, Bernhard Mauerer, Johanna Andris, Christopher Berlin, Thomas Wieder, Rebecca Kesselring
Publikováno v:
Cells, Vol 12, Iss 1, p 138 (2022)
Colorectal cancer (CRC) is one of the most frequent tumor entities worldwide with only limited therapeutic options. CRC is not only a genetic disease with several mutations in specific oncogenes and/or tumor suppressor genes such as APC, KRAS, PIC3CA
Externí odkaz:
https://doaj.org/article/41ea724702614176aefd57980ed8b55a
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Immune checkpoint molecules represent physiological brakes of the immune system that are essential for the maintenance of immune homeostasis and prevention of autoimmunity. By inhibiting these negative regulators of the immune response, immune checkp
Externí odkaz:
https://doaj.org/article/717e52a847d14e61a2bf5d7855c11f08
Autor:
Annette Thiel, Rebecca Kesselring, Ralph Pries, Alexander Puzik, Nadine Wittkopf, Barbara Wollenberg
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15997 (2011)
Human Plasmacytoid Dendritic Cells (PDCs) infiltrating solid tumor tissues and draining lymph nodes of Head and Neck Squamous Cell Carcinoma (HNSCC) show an impaired immune response. In addition to an attenuated secretion of IFN-α little is known ab
Externí odkaz:
https://doaj.org/article/02746d1e7e70423aa0ccc253900a6179
Autor:
Roland Schüle, Eric Metzger, Rebecca Kesselring, Stefan Fichtner-Feigl, Florian R. Greten, Valentina Petrocelli, Mark Schmitt, Karsten Rippe, Lisa Marx, Stephan M. Tirier, Sylvia Urban, Dominica Willmann, Félicie Cottard, Christopher Berlin
File with all the Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a9cf8a88342f87eb3f53092e1c8605
https://doi.org/10.1158/0008-5472.22430692
https://doi.org/10.1158/0008-5472.22430692
Autor:
Roland Schüle, Eric Metzger, Rebecca Kesselring, Stefan Fichtner-Feigl, Florian R. Greten, Valentina Petrocelli, Mark Schmitt, Karsten Rippe, Lisa Marx, Stephan M. Tirier, Sylvia Urban, Dominica Willmann, Félicie Cottard, Christopher Berlin
Colorectal cancer is among the leading causes of cancer-associated deaths worldwide. Treatment failure and tumor recurrence due to survival of therapy-resistant cancer stem/initiating cells represent major clinical issues to overcome. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48d5c76e37676e1e58da97cf971dc2e8
https://doi.org/10.1158/0008-5472.c.6513688.v1
https://doi.org/10.1158/0008-5472.c.6513688.v1
Autor:
Roland Schüle, Eric Metzger, Rebecca Kesselring, Stefan Fichtner-Feigl, Florian R. Greten, Valentina Petrocelli, Mark Schmitt, Karsten Rippe, Lisa Marx, Stephan M. Tirier, Sylvia Urban, Dominica Willmann, Félicie Cottard, Christopher Berlin
File with all the Supplementary Tables (Supplementary Tables S1-S3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60306b50fa407b0ac15144745c072364
https://doi.org/10.1158/0008-5472.22430689.v1
https://doi.org/10.1158/0008-5472.22430689.v1
Autor:
Emilia Neuwirt, Giovanni Magnani, Tamara Ćiković, Svenja Wöhrle, Larissa Fischer, Anna Kostina, Stephan Flemming, Nora J. Fischenich, Benedikt S. Saller, Oliver Gorka, Steffen Renner, Claudia Agarinis, Christian N. Parker, Andreas Boettcher, Christopher J. Farady, Rebecca Kesselring, Christopher Berlin, Rolf Backofen, Marta Rodriguez-Franco, Clemens Kreutz, Marco Prinz, Martina Tholen, Thomas Reinheckel, Thomas Ott, Christina J. Groß, Philipp J. Jost, Olaf Groß
Publikováno v:
Science Signaling. 16
Inflammasomes are intracellular protein complexes that promote an inflammatory host defense in response to pathogens and damaged or neoplastic tissues and are implicated in inflammatory disorders and therapeutic-induced toxicity. We investigated the