Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rebecca K.M. Protheroe"'
Autor:
Fiona M. Ross, Laura Chiecchio, GianPaolo Dagrada, Rebecca K.M. Protheroe, David M. Stockley, Christine J. Harrison, Nicholas C.P. Cross, Alex J. Szubert, Mark T. Drayson, Gareth J. Morgan
Publikováno v:
Haematologica, Vol 95, Iss 7 (2010)
A large series of plasma cell dyscrasias (n=2207) was examined for translocations which deregulate the MAF genes, t(14;20)(q32;q12) and t(14;16)(q32;q23), and their disease behavior was compared to a group characterized by the t(4;14)(p16;q32) where
Externí odkaz:
https://doaj.org/article/2d1f91276fde424a95346b51dd4a947b
Autor:
Laura Chiecchio, Gian Paolo Dagrada, Ashraf H. Ibrahim, Elizabet Dachs Cabanas, Rebecca K.M. Protheroe, David M. Stockley, Kim H. Orchard, Nicholas C.P. Cross, Christine J. Harrison, Fiona M. Ross
Publikováno v:
Haematologica, Vol 94, Iss 12 (2009)
Background Multiple myeloma, monoclonal gammopathy of undetermined significance and smoldering multiple myeloma harbor common chromosomal abnormalities but the prevalence and relative association of aberrations in these diagnostic groups remains cont
Externí odkaz:
https://doaj.org/article/e9b3497140394e78bac7e16c57923a48
Autor:
Laura Chiecchio, Gian Paolo Dagrada, Rebecca K.M. Protheroe, David M. Stockley, Alastair G. Smith, Kim H. Orchard, Nicholas C.P. Cross, Christine J. Harrison, Fiona M. Ross
Publikováno v:
Haematologica, Vol 94, Iss 7 (2009)
We report serial genetic studies on a young female patient initially diagnosed with asymptomatic smouldering myeloma who progressed to symptomatic myeloma 4.5 years after presentation. An unbalanced translocation, der(14)t(4;14)(p16;q32), was initial
Externí odkaz:
https://doaj.org/article/aeb9beceb0af4767ad4210a825afded8
Autor:
Faith E. Davies, David M. Stockley, Gianpaolo Dagrada, Zoe J. Konn, Fiona M. Ross, Brian A Walker, Paola E. Leone, David W. Johnson, Walter M Gregory, Laura Chiecchio, Matthew W Jenner, Rebecca K.M. Protheroe, Gareth J. Morgan, David Gonzalez, Kevin Boyd, Nicholas J. Dickens
Publikováno v:
Blood. 116:e56-e65
To obtain a comprehensive genomic profile of presenting multiple myeloma cases we performed high-resolution single nucleotide polymorphism mapping array analysis in 114 samples alongside 258 samples analyzed by U133 Plus 2.0 expression array (Affymet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c846ed1b0f8da4ebe36f8ed0752dd5d7
https://doi.org/10.1182/blood-2010-04-279596
https://doi.org/10.1182/blood-2010-04-279596
Autor:
Nicholas C.P. Cross, Rebecca K.M. Protheroe, Gianpaolo Dagrada, Laura Chiecchio, Fiona M. Ross, David M. Stockley, Mark T. Drayson, Alex J Szubert, Gareth J. Morgan, Christine J. Harrison
Publikováno v:
Haematologica. 95:1221-1225
A large series of plasma cell dyscrasias (n=2207) was examined for translocations which deregulate the MAF genes, t(14;20)(q32;q12) and t(14;16)(q32;q23), and their disease behavior was compared to a group characterized by the t(4;14)(p16;q32) where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a9ede6f1915c4adf491349ce11a343
https://doi.org/10.3324/haematol.2009.016329
https://doi.org/10.3324/haematol.2009.016329
Autor:
Christine J. Harrison, Nicholas C.P. Cross, Gianpaolo Dagrada, Kim Orchard, David M. Stockley, Fiona M. Ross, Laura Chiecchio, Rebecca K.M. Protheroe, Ashraf H. Ibrahim, Elizabet Dachs Cabanas
Publikováno v:
Haematologica. 94:1708-1713
Background Multiple myeloma, monoclonal gammopathy of undetermined significance and smoldering multiple myeloma harbor common chromosomal abnormalities but the prevalence and relative association of aberrations in these diagnostic groups remains cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775653979a639f9964ee5b84dd815c28
https://doi.org/10.3324/haematol.2009.011064
https://doi.org/10.3324/haematol.2009.011064
Autor:
Jose L.R. Brito, Nicholas J. Dickens, Matthew W Jenner, Rebecca K.M. Protheroe, David Gonzalez, Gianpaolo Dagrada, Paola E. Leone, Fiona M. Ross, Faith E. Davies, Gareth J. Morgan, David W. Johnson, Laura Chiecchio, Selina Chen-Kiang, Brian A Walker, Monica Else
Publikováno v:
Clinical Cancer Research. 14:6033-6041
Purpose: Deletions of chromosome 1 have been described in 7% to 40% of cases of myeloma with inconsistent clinical consequences. CDKN2C at 1p32.3 has been identified in myeloma cell lines as the potential target of the deletion. We tested the clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d820a82a78a7fdfc7f4739c64821d90
https://doi.org/10.1158/1078-0432.ccr-08-0347
https://doi.org/10.1158/1078-0432.ccr-08-0347
Autor:
Fiona M. Ross, Gareth J. Morgan, Gianpaolo Dagrada, T Parker, C Rudduck, A Wechalekar, Rebecca K.M. Protheroe, E.D. Cabanas, A H Ibrahim, Mathew Nightingale, Kim Orchard, Christine J. Harrison, Nicholas C.P. Cross, Kan Luk Cheung, Laura Chiecchio
Publikováno v:
Leukemia. 20:1610-1617
In myeloma, the prognostic impact of different strategies used to detect chromosome 13 deletion (Delta13) remains controversial. To address this, we compared conventional cytogenetics and interphase fluorescence in situ hybridization (iFISH) in a lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f0fc7b6e0739b819791e9460d4dc3f
https://doi.org/10.1038/sj.leu.2404304
https://doi.org/10.1038/sj.leu.2404304
Autor:
Fiona M. Ross, A.H. Ibrahim, Laura Chiecchio, Paul Strike, Gareth J. Morgan, A. Vilain-Holmes, Amy V. Jones, J L Gunasekera, M O Winfield, Rebecca K.M. Protheroe, Christine J. Harrison, Nicholas C.P. Cross
Publikováno v:
Leukemia. 19:1634-1642
A simple high throughput micro-fluorescence in situ hybridisation technique (FISH) was used to detect chromosome 13 deletions (delta13), immunoglobulin heavy chain (IgH) rearrangements, t(11;14)(q13;q32), t(4;14)(p16;q32), t(14;16)(q23;q32), p53 loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5428757e960e2b1885b2dce85f6f59cf
https://doi.org/10.1038/sj.leu.2403857
https://doi.org/10.1038/sj.leu.2403857
Autor:
Fiona M. Ross, Alastair G. Smith, Kim Orchard, Laura Chiecchio, David M. Stockley, Rebecca K.M. Protheroe, Christine J. Harrison, Nicholas C.P. Cross, Gianpaolo Dagrada
We report serial genetic studies on a young female patient initially diagnosed with asymptomatic smouldering myeloma who progressed to symptomatic myeloma 4.5 years after presentation. An unbalanced translocation, der(14)t(4;14)(p16;q32), was initial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc98bb754dabd546a7f980c147f03cd
https://europepmc.org/articles/PMC2704316/
https://europepmc.org/articles/PMC2704316/
