Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Rebecca K Simmons"'
Autor:
Nicole H T M Dukers-Muijrers, Hans Bosma, Miranda T Schram, Rebecca K Simmons, Nicolaas C Schaper, Omar Silverman-Retana, Stephanie Brinkhues, Adam Hulman, Martien C J M van Dongen, Daniel R Witte
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
Introduction We compared the degree of spousal concordance in a set of detailed pathophysiological markers and risk factors for type 2 diabetes to understand where in the causal cascade spousal similarities are most relevant.Research design and metho
Externí odkaz:
https://doaj.org/article/76bd243f887a4a7b885db963ab138696
Autor:
Morten Charles, Mette V Skriver, Simon J Griffin, Rebecca K Simmons, Daniel R Witte, Else-Marie Dalsgaard, Torsten Lauritzen, Annelli Sandbæk
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0170697 (2017)
INTRODUCTION:Very few studies have examined the potential spill-over effect of a trial intervention in general practice. We investigated whether training and support of general practitioners in the intensive treatment of people with screen-detected d
Externí odkaz:
https://doaj.org/article/8d58b8f29bce41b1bf6723ff83463315
Autor:
Rebecca K Simmons, Knut Borch-Johnsen, Torsten Lauritzen, Guy EHM Rutten, Annelli Sandbæk, Maureen van den Donk, James A Black, Libo Tao, Edward CF Wilson, Melanie J Davies, Kamlesh Khunti, Stephen J Sharp, Nicholas J Wareham, Simon J Griffin
Publikováno v:
Health Technology Assessment, Vol 20, Iss 64 (2016)
Background: Intensive treatment (IT) of cardiovascular risk factors can halve mortality among people with established type 2 diabetes but the effects of treatment earlier in the disease trajectory are uncertain. Objective: To quantify the cost-effect
Externí odkaz:
https://doaj.org/article/570517e2d50449fbbbd0fd13c37ca1b3
Autor:
Parinya Chamnan, Rebecca K Simmons, Stephen J Sharp, Kay-Tee Khaw, Nicholas J Wareham, Simon J Griffin
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0147417 (2016)
BackgroundFramingham risk equations are widely used to predict cardiovascular disease based on health information from a single time point. Little is known regarding use of information from repeat risk assessments and temporal change in estimated car
Externí odkaz:
https://doaj.org/article/cc174d7a454c45ebaa70e4fd206b14fd
Autor:
Andrew J M Cooper, Rebecca K Simmons, Diana Kuh, Soren Brage, Rachel Cooper, NSHD scientific and data collection team
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126465 (2015)
To investigate the associations of time spent sedentary, in moderate-to-vigorous-intensity physical activity (MVPA) and physical activity energy expenditure (PAEE) with physical capability measures at age 60-64 years.Time spent sedentary and in MVPA
Externí odkaz:
https://doaj.org/article/d35a0fd9be074159bac05cc2142c97ab
Autor:
Rianne M van der Linde, Nahal Mavaddat, Robert Luben, Carol Brayne, Rebecca K Simmons, Kay Tee Khaw, Ann Louise Kinmonth
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65290 (2013)
Self-rated health (SRH) predicts chronic disease morbidity including cardiovascular disease (CVD). In a population-based cohort, we examined the association between SRH and incident CVD and whether this association was independent of socio-demographi
Externí odkaz:
https://doaj.org/article/cd5a1335368b4572bd69ed0fea35d700
Publikováno v:
Diabetic Medicine
Diabet. Med. 29, 893–904 (2012) Abstract Background Diabetes risk assessment has been proposed as part of the National Health Service Health Checks programme, and HbA1c has recently been recommended as a diagnostic test for diabetes at a threshold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217baf16d3aaa0a3f8f11546a79889cf
Autor:
Sally Martin, Daniel Poppe, Nelly Olova, Conor O’Leary, Elena Ivanova, Jahnvi Pflueger, Jennifer Dechka, Rebecca K. Simmons, Helen M. Cooper, Wolf Reik, Ryan Lister, Ernst J. Wolvetang
Publikováno v:
Genes; Volume 14; Issue 5; Pages: 957
DNA methylation in neurons is directly linked to neuronal genome regulation and maturation. Unlike other tissues, vertebrate neurons accumulate high levels of atypical DNA methylation in the CH sequence context (mCH) during early postnatal brain deve
Autor:
Charles A. Herring, Rebecca K. Simmons, Saskia Freytag, Daniel Poppe, Joel J.D. Moffet, Jahnvi Pflueger, Sam Buckberry, Dulce B. Vargas-Landin, Olivier Clément, Enrique Goñi Echeverría, Gavin J. Sutton, Alba Alvarez-Franco, Rui Hou, Christian Pflueger, Kerrie McDonald, Jose M. Polo, Alistair R.R. Forrest, Anna K. Nowak, Irina Voineagu, Luciano Martelotto, Ryan Lister
Publikováno v:
Cell. 185:4428-4447.e28
Human brain development is underpinned by cellular and molecular reconfigurations continuing into the third decade of life. To reveal cell dynamics orchestrating neural maturation, we profiled human prefrontal cortex gene expression and chromatin acc
Autor:
Leigh T. Flynn, Huda Akil, Joshua L. Cohen, Sarah M. Clinton, Xiaowei Wu, Nateka L. Jackson, Chelsea R. McCoy, Rebecca K. Simmons, Matthew E. Glover, Travis Ptacek, Elliot J. Lefkowitz
Publikováno v:
J Neurosci
There is growing evidence of abnormal epigenetic processes playing a role in the neurobiology of psychiatric disorders, although the precise nature of these anomalies remains largely unknown. To study neurobiological (including epigenetic) factors th