Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Rebecca Jarvis"'
Autor:
Zaher ElBeck, Mohammad Bakhtiar Hossain, Humam Siga, Nikolay Oskolkov, Fredrik Karlsson, Julia Lindgren, Anna Walentinsson, Dominique Koppenhöfer, Rebecca Jarvis, Roland Bürli, Tanguy Jamier, Elske Franssen, Mike Firth, Andrea Degasperi, Claus Bendtsen, Robert I. Menzies, Katrin Streckfuss-Bömeke, Michael Kohlhaas, Alexander G. Nickel, Lars H. Lund, Christoph Maack, Ákos Végvári, Christer Betsholtz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract While excessive production of reactive oxygen species (ROS) is a characteristic hallmark of numerous diseases, clinical approaches that ameliorate oxidative stress have been unsuccessful. Here, utilizing multi-omics, we demonstrate that in c
Externí odkaz:
https://doaj.org/article/8cb734f3e6db454ca663dbe7df2cc0bb
Publikováno v:
Nature-Based Solutions, Vol 4, Iss , Pp 100073- (2023)
Externí odkaz:
https://doaj.org/article/fafdc375783e49c6b3ae18d390cbf8be
Autor:
Lidia Wrobel, Sandra M. Hill, Alvin Djajadikerta, Marian Fernandez-Estevez, Cansu Karabiyik, Avraham Ashkenazi, Victoria J. Barratt, Eleanna Stamatakou, Anders Gunnarsson, Timothy Rasmusson, Eric W. Miele, Nigel Beaton, Roland Bruderer, Yuehan Feng, Lukas Reiter, M. Paola Castaldi, Rebecca Jarvis, Keith Tan, Roland W. Bürli, David C. Rubinsztein
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Several neurodegenerative diseases are characterized by the aggregation of cytoplasmic proteins. Here, the authors demonstrate that the small molecule SMER28 activates VCP, which enhances both autophagic and proteasomal clearance of aggregate-prone p
Externí odkaz:
https://doaj.org/article/02631720e7494834abf742bdf764ec8e
Autor:
Kathryn Greenwood, Rebecca Webb, Jenny Gu, David Fowler, Richard de Visser, Stephen Bremner, Iga Abramowicz, Nicky Perry, Stuart Clark, Anastacia O’Donnell, Dan Charlton, Rebecca Jarvis, Philippa Garety, Sunil Nandha, Belinda Lennox, Louise Johns, Shanaya Rathod, Peter Phiri, Paul French, Heather Law, Jo Hodgekins, Michelle Painter, Cate Treise, James Plaistow, Francis Irwin, Rose Thompson, Tanya Mackay, Carl R. May, Andy Healey, Richard Hooper, Emmanuelle Peters
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-20 (2021)
Abstract Background Early Intervention in Psychosis (EIP) services improve health outcomes for young people with psychosis in the medium–long term, but 25% of young people disengage in the first 12 months with costs to their mental health, families
Externí odkaz:
https://doaj.org/article/6963d320b2394164b4aa451796b0f25a
Autor:
Natsuko Macabuag, William Esmieu, Perla Breccia, Rebecca Jarvis, Wesley Blackaby, Ovadia Lazari, Liudvikas Urbonas, Maria Eznarriaga, Rachel Williams, Annelieke Strijbosch, Rhea Van de Bospoort, Kim Matthews, Cole Clissold, Tammy Ladduwahetty, Huw Vater, Patrick Heaphy, Douglas G. Stafford, Hong-Jun Wang, John E. Mangette, George McAllister, Vahri Beaumont, Thomas F. Vogt, Hilary A. Wilkinson, Elizabeth M. Doherty, Celia Dominguez
Publikováno v:
Journal of medicinal chemistry. 65(18)
Huntington's disease (HD) is a lethal autosomal dominant neurodegenerative disorder resulting from a CAG repeat expansion in the huntingtin (
Publikováno v:
Clinical Psychology Forum. 1:65-71
Autor:
Joe Hollinghurst, Laura North, Tamas Szakmany, Richard Pugh, Gwyneth A Davies, Shanya Sivakumaran, Rebecca Jarvis, Martin Rolles, W Owen Pickrell, Ashley Akbari, Gareth Davies, Rowena Griffiths, Jane Lyons, Fatemeh Torabi, Richard Fry, Mike B Gravenor, Ronan A Lyons
Publikováno v:
Journal of the Royal Society of Medicine. 115:467-478
Objectives To better understand the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among healthcare workers, leading to recommendations for the prioritisation of personal protective equipment, testing, training and vac