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of 13
pro vyhledávání: '"Rebecca J. Linger"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Transgenic sexing strains (TSS) that carry conditional female lethal genes are advantageous for genetic control programs based on the sterile insect technique (SIT). It is desirable if females die early in development as larval diet is a maj
Externí odkaz:
https://doaj.org/article/8db48796cc434424b7070f1245e151fe
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141544 (2015)
In most animals that have X and Y sex chromosomes, chromosome-wide mechanisms are used to balance X-linked gene expression in males and females. In the fly Drosophila melanogaster, the dosage compensation mechanism also generally extends to X-linked
Externí odkaz:
https://doaj.org/article/90e881a167ff481d895f3c2dd0a86776
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Transgenic sexing strains (TSS) that carry conditional female lethal genes are advantageous for genetic control programs based on the sterile insect technique (SIT). It is desirable if females die early in development as larval diet is a major cost f
Autor:
R M Edman, Esther J. Belikoff, Sing-Hoi Sze, Maxwell J. Scott, Fang Li, Aaron M. Tarone, Rebecca J. Linger
Publikováno v:
Insect Molecular Biology. 24:58-70
The New World screwworm fly, Cochliomyia hominivorax, and the Australian sheep blow fly, Lucilia cuprina, are major pests of livestock. The sterile insect technique was used to eradicate C. hominivorax from North and Central America. This involved ar
Publikováno v:
Insect Biochemistry and Molecular Biology. 51:80-88
The New World screwworm and the Australian sheep blowfly Lucilia cuprina are devastating pests of livestock. The larvae of these species feed on the tissue of the living animal and can cause death if untreated. The sterile insect technique or SIT was
Autor:
Rebecca J. Linger, Fang Li, Esther J. Belikoff, Helen L. Fitzsimons, Holly A. Wantuch, Maxwell J. Scott, Ying Yan
Publikováno v:
BMC Biotechnology
Background Diabetes and its concurrent complications impact a significant proportion of the population of the US and create a large financial burden on the American health care system. FDA-approved maggot debridement therapy (MDT), the application of
Autor:
Rebecca J. Linger, Patricia A. Kruk
Publikováno v:
FEBS Journal. 277:3086-3096
Mutations in the tumor suppressor breast cancer susceptibility gene 1 (BRCA1), an important player in the DNA damage response, apoptosis, cell cycle regulation and transcription, confer a significantly elevated lifetime risk for breast and ovarian ca
Autor:
Jesse Roman, Mai Mohamed, Rebecca J. Linger, Patricia A. Kruk, Kimberly P. Dobrinski, Kamisha T. Woolery
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
Familial history remains the strongest risk factor for developing ovarian cancer (OC) and is associated with germline BRCA1 mutations, such as the 185delAG founder mutation. We sought to determine whether normal human ovarian surface epithelial (OSE)
Publikováno v:
Gynecologic oncology. 116(2)
Objective Aggressive clinical course and difficult detection of ovarian cancer are major challenges to improving patient survival and necessitate avid investigation into more effective therapeutic approaches. Understanding early molecular and patholo
Abstract 2030: A novel role for the 185delAG BRCA1 mutant protein, BRAT, in ovarian cancer pathology
Publikováno v:
Cancer Research. 71:2030-2030
Objective: Familial history is the strongest risk factor for developing ovarian cancer (OC) and is associated with BRCA1 truncation mutations, such as the founder mutation 185delAG. Studying these risk-associated mutations may reveal signaling pathwa