Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Rebecca J. Josephson"'
Autor:
Nicholas K. Foreman, Rajeev Vibhakar, Michael H. Handler, Phillip Reigan, Steffanie L. Furtek, Lindsey M. Hoffman, Diane K. Birks, Vladimir Amani, Jean M. Mulcahy Levy, Andrew M. Donson, Rebecca J. Josephson, Andrea M. Griesinger
Consensus NMF of 81 primary ependymoma samples at k = 3 delineates two posterior fossa subgroups in the study cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d4b4de8cf0516633c49ed30cddeae6
https://doi.org/10.1158/2326-6066.22538356
https://doi.org/10.1158/2326-6066.22538356
Autor:
Nicholas K. Foreman, Rajeev Vibhakar, Michael H. Handler, Phillip Reigan, Steffanie L. Furtek, Lindsey M. Hoffman, Diane K. Birks, Vladimir Amani, Jean M. Mulcahy Levy, Andrew M. Donson, Rebecca J. Josephson, Andrea M. Griesinger
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04baa86546daacfbe8b5565aecd3313f
https://doi.org/10.1158/2326-6066.22538359
https://doi.org/10.1158/2326-6066.22538359
Autor:
Nicholas K. Foreman, Rajeev Vibhakar, Michael H. Handler, Phillip Reigan, Steffanie L. Furtek, Lindsey M. Hoffman, Diane K. Birks, Vladimir Amani, Jean M. Mulcahy Levy, Andrew M. Donson, Rebecca J. Josephson, Andrea M. Griesinger
STAT3, IL-6 and inflammatory response pathway signaling associated gene expression is upregulated in Group A EPN.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8841ed33a212e3d2ce4d8f15e1dd8b
https://doi.org/10.1158/2326-6066.22538353
https://doi.org/10.1158/2326-6066.22538353
Autor:
Nicholas K. Foreman, Rajeev Vibhakar, Michael H. Handler, Phillip Reigan, Steffanie L. Furtek, Lindsey M. Hoffman, Diane K. Birks, Vladimir Amani, Jean M. Mulcahy Levy, Andrew M. Donson, Rebecca J. Josephson, Andrea M. Griesinger
Experimentally determined STAT3 upregulated genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ecc3d7b05a865dcb42cb4842888f2d8
https://doi.org/10.1158/2326-6066.22538338
https://doi.org/10.1158/2326-6066.22538338
Autor:
Nicholas K. Foreman, Rajeev Vibhakar, Michael H. Handler, Phillip Reigan, Steffanie L. Furtek, Lindsey M. Hoffman, Diane K. Birks, Vladimir Amani, Jean M. Mulcahy Levy, Andrew M. Donson, Rebecca J. Josephson, Andrea M. Griesinger
Ependymoma (EPN) in childhood is a brain tumor with substantial mortality. Inflammatory response has been identified as a molecular signature of high-risk Group A EPN. To better understand the biology of this phenotype and aid therapeutic development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6330a8fe64159ec46c088292dcf26114
https://doi.org/10.1158/2326-6066.c.6548749.v1
https://doi.org/10.1158/2326-6066.c.6548749.v1
Autor:
Nicholas K. Foreman, Rajeev Vibhakar, Michael H. Handler, Phillip Reigan, Steffanie L. Furtek, Lindsey M. Hoffman, Diane K. Birks, Vladimir Amani, Jean M. Mulcahy Levy, Andrew M. Donson, Rebecca J. Josephson, Andrea M. Griesinger
IL-6 is the driving cytokine for immune suppressive phenotype observed in 811 CM monocytes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b283044276d6b7b5bd54386cc2f7c9
https://doi.org/10.1158/2326-6066.22538341.v1
https://doi.org/10.1158/2326-6066.22538341.v1
Autor:
Nicholas K. Foreman, Rajeev Vibhakar, Michael H. Handler, Phillip Reigan, Steffanie L. Furtek, Lindsey M. Hoffman, Diane K. Birks, Vladimir Amani, Jean M. Mulcahy Levy, Andrew M. Donson, Rebecca J. Josephson, Andrea M. Griesinger
S3I-201 effects on cell cycle EPN cell line 811 and apoptosis in EPN cell line 723.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb804e3d7831af45b261e5caafcdc77
https://doi.org/10.1158/2326-6066.22538344.v1
https://doi.org/10.1158/2326-6066.22538344.v1
Autor:
Nicholas K. Foreman, Rajeev Vibhakar, Michael H. Handler, Phillip Reigan, Steffanie L. Furtek, Lindsey M. Hoffman, Diane K. Birks, Vladimir Amani, Jean M. Mulcahy Levy, Andrew M. Donson, Rebecca J. Josephson, Andrea M. Griesinger
Ratio of Group A EPN IL6/STAT3 pathway genes in tumor versus the myeloid compartments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280dd264660e6d5778af77d5fa08514d
https://doi.org/10.1158/2326-6066.22538350.v1
https://doi.org/10.1158/2326-6066.22538350.v1
Autor:
Jean M. Mulcahy Levy, Rajeev Vibhakar, Lindsey M. Hoffman, Vladimir Amani, Diane K. Birks, Michael H. Handler, Nicholas K. Foreman, Steffanie L. Furtek, Rebecca J. Josephson, Phillip Reigan, Andrea Griesinger, Andrew M. Donson
Ependymoma (EPN) in childhood is a brain tumor with substantial mortality. Inflammatory response has been identified as a molecular signature of high-risk Group A EPN. To better understand the biology of this phenotype and aid therapeutic development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6c850f684cac3f44cf5728a5c4dd22
https://europepmc.org/articles/PMC4596749/
https://europepmc.org/articles/PMC4596749/
Autor:
Kathleen Dorris, Diane K. Birks, Nicholas K. Foreman, Andrew M. Donson, Andrea Griesinger, Rebecca J. Josephson, Philip Reigan, Vladimir Amani, Michael H. Handler
Publikováno v:
Cancer Immunology Research. 3:B69-B69
To aid development of immunotherapy for poor outcome Group A ependymoma (EPN) in children we sought to identify the molecular pathway underlying the adverse pro-inflammatory phenotype associated with this molecular subgroup. We have previously shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da131bcff941522278fe2bc156fab20b
https://doi.org/10.1158/2326-6074.tumimm14-b69
https://doi.org/10.1158/2326-6074.tumimm14-b69
