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Autor:
Iwona Bujalska, A E Michael, Paul Stewart, Rachel Welsby, Marianthi Evagelatou, Dean P. Norgate, Brian A. Cooke, Brian A. Stedman, Rebecca J. Clarke, Joseph W. Antoniw, Alex Brennan
Publikováno v:
Molecular and Cellular Endocrinology. 132:43-52
To date, two isoforms of 11beta-hydroxysteroid dehydrogenase (11betaHSD) have been characterized: a low affinity, NADP+-dependent isoform (11betaHSD1) and a high affinity, NAD+-dependent isoform which metabolizes dexamethasone and is inhibited by cor