Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Rebecca J. Boohaker"'
Autor:
Yang Chen, Mingming Xiao, Yaqi Mo, Jinlu Ma, Yamei Han, Qing Li, Qinghua Zeng, Rebecca J. Boohaker, Joshua Fried, Yonghe Li, Han Wang, Bo Xu
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-19 (2024)
Abstract Background The activation of the DNA damage response (DDR) heavily relies on post-translational modifications (PTMs) of proteins, which play a crucial role in the prevention of genetic instability and tumorigenesis. Among these PTMs, palmito
Externí odkaz:
https://doaj.org/article/774e4c330964480d9ada5f488ef383f3
Autor:
Byungho Lim, Dabin Yoo, Younghwa Chun, Areum Go, Kyung-Jin Cho, Daeun Choi, Myoung Eun Jung, Ha Young Lee, Rebecca J. Boohaker, Jin Soo Lee, DooYoung Jung, Gildon Choi
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 4, Pp 1-5 (2022)
Externí odkaz:
https://doaj.org/article/1043286adf514d62864a0b916f54ebe0
Autor:
Amanda Cox, Daniel Nierenberg, Oscar Camargo, Eunkyung Lee, Amr S. Khaled, Joseph Mazar, Rebecca J. Boohaker, Tamarah J. Westmoreland, Annette R. Khaled
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Chaperonin containing TCP1 (CCT/TRiC) is a multi-subunit protein folding complex that enables the cancer phenotype to emerge from the mutational landscape that drives oncogenesis. We and others linked increased expression of CCT subunits to advanced
Externí odkaz:
https://doaj.org/article/45119ebc4cf14bbc91ac699144326562
Autor:
Mingming Xiao, Joshua S. Fried, Jinlu Ma, Yang Su, Rebecca J. Boohaker, Qinghua Zeng, Yaqi Mo, Fanbiao Meng, Rong Xiang, Bo Xu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/50d117073eee4c68b952ef1fd882c7f6
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
GLI1 is a transcriptional effector at the terminal end of the Hedgehog signaling (Hh) pathway and is tightly regulated during embryonic development and tissue patterning/differentiation. GLI1 has low-level expression in differentiated tissues, howeve
Externí odkaz:
https://doaj.org/article/bf7908b0c6ea478f87961b9505080bac
Autor:
Ruowen Zhang, Jinlu Ma, Justin T. Avery, Vijaya Sambandam, Theresa H. Nguyen, Bo Xu, Mark J. Suto, Rebecca J. Boohaker
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Resistance to radiation and chemotherapy in colorectal cancer (CRC) patients contribute significantly to refractory disease and disease progression. Herein, we provide mechanistic rationale for acquired or inherent chemotherapeutic resistance to the
Externí odkaz:
https://doaj.org/article/00de545de3a84180bfc309628ab6dd67
Autor:
Byungho Lim, Dabin Yoo, Younghwa Chun, Areum Go, Ji Yeon Kim, Ha Young Lee, Rebecca J. Boohaker, Kyung-Jin Cho, Sunjoo Ahn, Jin Soo Lee, DooYoung Jung, Gildon Choi
Publikováno v:
Cancers; Volume 15; Issue 6; Pages: 1737
Epigenetic dysregulation characterized by aberrant DNA hypermethylation is a hallmark of cancer, and it can be targeted by hypomethylating agents (HMAs). Recently, we described the superior therapeutic efficacy of a novel HMA, namely, NTX-301, when u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299d8f2ece4f475653328d9383d58895
Publikováno v:
Journal of Clinical Oncology. 40:e15056-e15056
e15056 Background: The alpha fetoprotein (AFP) receptor is an oncofetal antigen and a novel target for cancer therapeutics. It is highly expressed on the surfaces of many cancers and myeloid derived suppressor cells (MDSCs) but absent on normal tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99b2a7272c41804d54c135ed4214beb5
https://doi.org/10.1200/jco.2022.40.16_suppl.e15056
https://doi.org/10.1200/jco.2022.40.16_suppl.e15056
Autor:
Pankit Vachhani, Guru Subramanian Guru Murthy, Omer Jamy, Kimo Bachiashvili, Sravanti Rangaraju, Tonya Cole, Corinne E Augelli-Szafran, Rebecca J Boohaker, Omar Moukha-Chafiq, Lynae J Hanks, Karr Stinson, Doo Young Jung, Ehab L. Atallah, Ravi Bhatia
Publikováno v:
Journal of Clinical Oncology. 40:TPS7077-TPS7077
TPS7077 Background: Patients with relapsed and/or refractory (r/r) myelodysplastic syndrome (MDS), chronic myelomonocytic leukemia (CMML), and acute myeloid leukemia (AML) who are not candidates for stem-cell transplantation have dismal outcomes. Nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::173560f77c0c927b46d6ccb7ea0fedf2
https://doi.org/10.1200/jco.2022.40.16_suppl.tps7077
https://doi.org/10.1200/jco.2022.40.16_suppl.tps7077
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
GLI1 is a transcriptional effector at the terminal end of the Hedgehog signaling (Hh) pathway and is tightly regulated during embryonic development and tissue patterning/differentiation. GLI1 has low-level expression in differentiated tissues, howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc16a144928ed04c980063e810e8e874
https://doi.org/10.3389/fonc.2021.673154
https://doi.org/10.3389/fonc.2021.673154