Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Rebecca J Willcocks"'
Autor:
Alison M Barnard, Rebecca J Willcocks, Erika L Finanger, Michael J Daniels, William T Triplett, William D Rooney, Donovan J Lott, Sean C Forbes, Dah-Jyuu Wang, Claudia R Senesac, Ann T Harrington, Richard S Finkel, Barry S Russman, Barry J Byrne, Gihan I Tennekoon, Glenn A Walter, H Lee Sweeney, Krista Vandenborne
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194283 (2018)
OBJECTIVE:To provide evidence for quantitative magnetic resonance (qMR) biomarkers in Duchenne muscular dystrophy by investigating the relationship between qMR measures of lower extremity muscle pathology and functional endpoints in a large ambulator
Externí odkaz:
https://doaj.org/article/e8dfd05ea09445269c042c5cef248456
Autor:
Sean C Forbes, Rebecca J Willcocks, William T Triplett, William D Rooney, Donovan J Lott, Dah-Jyuu Wang, Jim Pollaro, Claudia R Senesac, Michael J Daniels, Richard S Finkel, Barry S Russman, Barry J Byrne, Erika L Finanger, Gihan I Tennekoon, Glenn A Walter, H Lee Sweeney, Krista Vandenborne
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106435 (2014)
IntroductionDuchenne muscular dystrophy (DMD) is an X-linked recessive disorder that results in functional deficits. However, these functional declines are often not able to be quantified in clinical trials for DMD until after age 7. In this study, w
Externí odkaz:
https://doaj.org/article/b1ddd295609e4a84bb30590f29b6277c
Autor:
Rebecca J. Willcocks, Alison M. Barnard, Michael J. Daniels, Sean C. Forbes, William T. Triplett, John F. Brandsema, Erika L. Finanger, William D. Rooney, Sarah Kim, Dah‐Jyuu Wang, Donovan J. Lott, Claudia R. Senesac, Glenn A. Walter, H. Lee Sweeney, Krista Vandenborne
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 1, Pp 67-78 (2024)
Abstract Objective Magnetic resonance (MR) measures of muscle quality are highly sensitive to disease progression and predictive of meaningful functional milestones in Duchenne muscular dystrophy (DMD). This investigation aimed to establish the repro
Externí odkaz:
https://doaj.org/article/4a848dd8b4bb4a98b68cbbe201dd5627
Autor:
Sarah Kim, Rebecca J. Willcocks, Michael J. Daniels, Juan Francisco Morales, Deok Yong Yoon, William T. Triplett, Alison M. Barnard, Daniela J. Conrado, Varun Aggarwal, Ramona Belfiore‐Oshan, Terina N. Martinez, Glenn A. Walter, William D. Rooney, Krista Vandenborne
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 10, Pp 1437-1449 (2023)
Abstract Although regulatory agencies encourage inclusion of imaging biomarkers in clinical trials for Duchenne muscular dystrophy (DMD), industry receives minimal guidance on how to use these biomarkers most beneficially in trials. This study aims t
Externí odkaz:
https://doaj.org/article/4d70ad360e114fe3be45ffb256d0e944
Autor:
Giacomo P. Comi, Erik H. Niks, Krista Vandenborne, Claudia M. Cinnante, Hermien E. Kan, Rebecca J. Willcocks, Daniele Velardo, Francesca Magri, Michela Ripolone, Jules J. van Benthem, Nienke M. van de Velde, Simone Nava, Laura Ambrosoli, Sara Cazzaniga, Paolo U. Bettica
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ObjectiveNo treatments are approved for Becker muscular dystrophy (BMD). This study investigated the efficacy and safety of givinostat, a histone deacetylase pan-inhibitor, in adults with BMD.MethodsMales aged 18–65 years with a diagnosis of BMD co
Externí odkaz:
https://doaj.org/article/ef5313913e3541e8afd1fe92d354ed17
Autor:
Alison M Barnard, David W Hammers, William T Triplett, Sarah Kim, Sean C Forbes, Rebecca J Willcocks, Michael J Daniels, Claudia R Senesac, Donovan J Lott, Ishu Arpan, William D Rooney, Richard T Wang, Stanley F Nelson, H Lee Sweeney, Krista Vandenborne, Glenn A Walter
Publikováno v:
Neurology
Background and Objectives:Duchenne muscular dystrophy (DMD) is a progressive muscle degenerative disorder with a well-characterized disease phenotype but considerable interindividual heterogeneity that is not well understood. The aim of the study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bd59c400a798777962bdaf85f08030
https://doi.org/10.1212/wnl.0000000000201163
https://doi.org/10.1212/wnl.0000000000201163
Autor:
Gihan Tennekoon, Maria Cecilia Mancini, Richard S. Finkel, Sabrina W. Yum, Sean C. Forbes, A. Nichols, Joanne M. Donovan, H. Lee Sweeney, Glenn A. Walter, Angelika Fretzen, William T. Triplett, Krista Vandenborne, James MacDougall, Erika Finanger, P. Bista, Rebecca J. Willcocks, Perry B. Shieh, William D. Rooney
Publikováno v:
Neuromuscular Disorders. 31:385-396
Chronic activation of NF-κB is a key driver of muscle degeneration and suppression of muscle regeneration in Duchenne muscular dystrophy. Edasalonexent (CAT-1004) is an orally-administered novel small molecule that covalently links two bioactive com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2fa34a107912e09b9d437a015defaf4
https://doi.org/10.1016/j.nmd.2021.02.001
https://doi.org/10.1016/j.nmd.2021.02.001
Autor:
Glenn A. Walter, Alison M. Barnard, Kirsten L. Zilke, Rebecca J. Willcocks, Kavya S Nair, Claudia R. Senesac, William D. Rooney, Krista Vandenborne, Ann T. Harrington, Donovan J. Lott
Publikováno v:
Phys Ther
Duchenne muscular dystrophy (DMD) is a muscle degenerative disorder that manifests in early childhood and results in progressive muscle weakness. Physical therapists have long been an important component of the multidisciplinary team caring for peopl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98727169da0f2689e49acdc7a6e66e8c
https://doi.org/10.1093/ptj/pzaa140
https://doi.org/10.1093/ptj/pzaa140
Autor:
Ann T. Harrington, John F. Brandsema, Glenn A. Walter, Rebecca J. Willcocks, Harneet Arora, Michael J. Daniels, William T. Triplett, Gihan Tennekoon, Krista Vandenborne, Claudia R. Senesac, Erika Finanger, H. Lee Sweeney, Alison M. Barnard, Donovan J. Lott, William D. Rooney, Sean C. Forbes, Dah Jyuu Wang, Umar Alabasi
Publikováno v:
Radiology
BACKGROUND: Upper extremity MRI and proton MR spectroscopy are increasingly considered to be outcome measures in Duchenne muscular dystrophy (DMD) clinical trials. PURPOSE: To demonstrate the feasibility of acquiring upper extremity MRI and proton ((
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f308dc946b30fa57f404285eb7254d08
https://doi.org/10.1148/radiol.2020192210
https://doi.org/10.1148/radiol.2020192210
Autor:
Alison M. Barnard, Glenn A. Walter, Krista Vandenborne, Amber M. Angell, Samuel L. Riehl, Rebecca J. Willcocks
Publikováno v:
J Neuromuscul Dis
Observational research benefits from inclusion of diverse cohorts. To characterize racial and ethnic diversity in observational and natural history research studies of Duchenne muscular dystrophy (DMD), highly cited and influential observational stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc1ddaac56b7555a1a4a9829f779759
https://doi.org/10.3233/jnd-190447
https://doi.org/10.3233/jnd-190447