Characterizing Lung Disease in Cystic Fibrosis with Magnetic Resonance Imaging and Airway Physiology.

Autor: Rebecca J Theilmann, Chantal Darquenne, Ann R Elliott, Barbara A Bailey, Douglas J Conrad

Publikováno v: PLoS ONE, Vol 11, Iss 6, p e0157177 (2016)

Translational investigations in cystic fibrosis (CF) have a need for improved quantitative and longitudinal measures of disease status. To establish a non-invasive quantitative MRI technique to monitor lung health in patients with CF and correlate MR

Externí odkaz: https://doaj.org/article/3a66c7672eb947a08844d1568af64dd9

Detection of Chronic Blast-Related Mild Traumatic Brain Injury with Diffusion Tensor Imaging and Support Vector Machines

Autor: Deborah L. Harrington, Po-Ya Hsu, Rebecca J. Theilmann, Annemarie Angeles-Quinto, Ashley Robb-Swan, Sharon Nichols, Tao Song, Lu Le, Carl Rimmele, Scott Matthews, Kate A. Yurgil, Angela Drake, Zhengwei Ji, Jian Guo, Chung-Kuan Cheng, Roland R. Lee, Dewleen G. Baker, Mingxiong Huang

Publikováno v: Diagnostics, Vol 12, Iss 4, p 987 (2022)

Blast-related mild traumatic brain injury (bmTBI) often leads to long-term sequalae, but diagnostic approaches are lacking due to insufficient knowledge about the predominant pathophysiology. This study aimed to build a diagnostic model for future ve

Externí odkaz: https://doaj.org/article/64f196269bfd4f8f8e8a3463c64c972a

Pathogenesis of obstructive sleep apnea in people living with HIV

Autor: Jeremy E. Orr, Rebecca J. Theilmann, Charles B. Hicks, Chantal Darquenne, Pamela N. DeYoung, Sonia Jain, Maile Y. Karris, Robert L. Owens, Christopher N. Schmickl, Atul Malhotra, Bradley A. Edwards

Publikováno v: J Appl Physiol (1985)
Journal of applied physiology (Bethesda, Md. : 1985), vol 131, iss 6

Obstructive sleep apnea (OSA) is highly prevalent in people living with human immunodeficiency virus (HIV) (PLWH), and it might contribute to frequently reported symptoms and comorbidities. Traditional risk factors for OSA are often absent in PLWH, s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a0dc92632d0e9be868f6421bd803ab
https://doi.org/10.1152/japplphysiol.00591.2021

Single-subject-based whole-brain MEG slow-wave imaging approach for detecting abnormality in patients with mild traumatic brain injury

Autor: Ming-Xiong Huang, Sharon Nichols, Dewleen G. Baker, Ashley Robb, Annemarie Angeles, Kate A. Yurgil, Angela Drake, Michael Levy, Tao Song, Robert McLay, Rebecca J. Theilmann, Mithun Diwakar, Victoria B. Risbrough, Zhengwei Ji, Charles W. Huang, Douglas G. Chang, Deborah L. Harrington, Laura Muzzatti, Jose M. Canive, J. Christopher Edgar, Yu-Han Chen, Roland R. Lee

Publikováno v: NeuroImage: Clinical, Vol 5, Iss C, Pp 109-119 (2014)

Traumatic brain injury (TBI) is a leading cause of sustained impairment in military and civilian populations. However, mild TBI (mTBI) can be difficult to detect using conventional MRI or CT. Injured brain tissues in mTBI patients generate abnormal s

Externí odkaz: https://doaj.org/article/2fbfa5880b654a0b9799bfefa7e37d18

Prone positioning redistributes gravitational stress in the lung in normal conditions and in simulations of oedema

Autor: Liza Botros, Tatsuya J. Arai, Rui Carlos Sá, Abhilash S. Kizhakke Puliyakote, Susan R. Hopkins, Sebastiaan Holverda, G. Kim Prisk, Harm Jan Bogaard, Rebecca J. Theilmann

Publikováno v: Experimental Physiology. Wiley-Blackwell Publishing Ltd
Kizhakke Puliyakote, A S, Holverda, S, Sá, R C, Arai, T J, Theilmann, R J, Botros, L, Bogaard, H J, Prisk, G K & Hopkins, S R 2020, ' Prone positioning redistributes gravitational stress in the lung in normal conditions and in simulations of oedema ', Experimental Physiology . https://doi.org/10.1113/EP089037
Exp Physiol

New Findings: What is the central question of this study? How does the interaction between posture and gravity affect the stresses on the lung, particularly in highly inflated gravitationally non-dependent regions, which are potentially vulnerable to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b8a8846018fd640d97f720cd4e7bd4
https://research.vumc.nl/en/publications/78aa5a13-366a-4de5-a66a-a387aa426f18