Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Rebecca J Shipley"'
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 7, p e1009142 (2021)
Millions of people worldwide are affected by peripheral nerve injuries (PNI), involving billions of dollars in healthcare costs. Common outcomes for patients include paralysis and loss of sensation, often leading to lifelong pain and disability. Engi
Externí odkaz:
https://doaj.org/article/2a47eba674af43cba46556bdd0190069
Autor:
Hannah West, Fiona Roberts, Paul Sweeney, Simon Walker-Samuel, Joseph Leedale, Helen Colley, Craig Murdoch, Rebecca J Shipley, Steven Webb
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254208 (2021)
Nanoparticles have the potential to increase the efficacy of anticancer drugs whilst reducing off-target side effects. However, there remain uncertainties regarding the cellular uptake kinetics of nanoparticles which could have implications for nanop
Externí odkaz:
https://doaj.org/article/81b955807a9144d8933128dc95e0bd7e
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 6, p e1006751 (2019)
Cancers exhibit spatially heterogeneous, unique vascular architectures across individual samples, cell-lines and patients. This inherently disorganised collection of leaky blood vessels contribute significantly to suboptimal treatment efficacy. Precl
Externí odkaz:
https://doaj.org/article/bce192d150c8457cbfc425ed5707bd65
Autor:
Iva Burova, Carlotta Peticone, David De Silva Thompson, Jonathan C Knowles, Ivan Wall, Rebecca J Shipley
Publikováno v:
Journal of Tissue Engineering, Vol 10 (2019)
Tissue engineering has the potential to augment bone grafting. Employing microcarriers as cell-expansion vehicles is a promising bottom-up bone tissue engineering strategy. Here we propose a collaborative approach between experimental work and mathem
Externí odkaz:
https://doaj.org/article/a6718410b22d451f81b5472cae2c1808
Publikováno v:
Journal of Tissue Engineering, Vol 10 (2019)
Research into cellular engineered bone grafts offers a promising solution to problems associated with the currently used auto- and allografts. Bioreactor systems can facilitate the development of functional cellular bone grafts by augmenting mass tra
Externí odkaz:
https://doaj.org/article/830822c17fa24aa5a2b2e374148c16b2
Autor:
David De Silva Thompson, Carlotta Peticone, Iva Burova, Rebecca J Shipley, Jonathan C Knowles, Hae-Won Kim, Martina Micheletti, Ivan B Wall
Publikováno v:
Journal of Tissue Engineering, Vol 10 (2019)
Tissue engineering is a promising approach for bone regeneration; yet challenges remain that limit successful translation to patients. It is necessary to understand how real-world manufacturing processes will affect the constituent cells and biomater
Externí odkaz:
https://doaj.org/article/5a490aaf1ff24e21b203dd8d935a959b
Autor:
Lloyd A C Chapman, Rebecca J Shipley, Jonathan P Whiteley, Marianne J Ellis, Helen M Byrne, Sarah L Waters
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105813 (2014)
The need for efficient and controlled expansion of cell populations is paramount in tissue engineering. Hollow fibre bioreactors (HFBs) have the potential to meet this need, but only with improved understanding of how operating conditions and cell se
Externí odkaz:
https://doaj.org/article/e8d7f704587d42848b1366cb2516c3ab
Autor:
Shahrokh Rahmani, Daniyal J. Jafree, Peter D. Lee, Paul Tfforeau, Joseph Jacob, Alexandre Bellier, Maximilian Ackermann, Danny D. Jonigk, Rebecca J. Shipley, David A. Long, Claire L. Walsh
Publikováno v:
bioRxiv
BackgroundThe kidney vasculature is exquisitely structured to orchestrate renal function. Structural profiling of the vasculature in intact rodent kidneys, has provided insights into renal haemodynamics and oxygenation, but has never been extended to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6c4bc0bee1a349f9b0846723770298
https://doi.org/10.1101/2023.03.28.534566
https://doi.org/10.1101/2023.03.28.534566
Publikováno v:
Biotechnology and Bioengineering. 119:1980-1996
Recent studies have explored the potential of tissue-mimetic scaffolds in encouraging nerve regeneration. One of the major determinants of the regenerative success of cellular nerve repair constructs (NRCs) is the local microenvironment, particularly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3de078b65896c469f3069d8628cf45
https://doi.org/10.1002/bit.28105
https://doi.org/10.1002/bit.28105
Publikováno v:
WIREs Mechanisms of Disease. 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee0da6094b6f24afffd6f7b77de41c05
https://doi.org/10.1002/wsbm.1593
https://doi.org/10.1002/wsbm.1593