Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Rebecca J Barr"'
Autor:
Isla S Mackenzie, Christopher J Hawkey, Ian Ford, Nicola Greenlaw, Filippo Pigazzani, Amy Rogers, Allan D Struthers, Alan G Begg, Li Wei, Anthony J Avery, Jaspal S Taggar, Andrew Walker, Suzanne L Duce, Rebecca J Barr, Jennifer S Dumbleton, Evelien D Rooke, Jonathan N Townend, Lewis D Ritchie, Thomas M MacDonald
Publikováno v:
Health Technology Assessment, Vol 28, Iss 18 (2024)
Abstract Background Allopurinol is a xanthine oxidase inhibitor that lowers serum uric acid and is used to prevent acute gout flares in patients with gout. Observational and small interventional studies have suggested beneficial cardiovascular effect
Externí odkaz:
https://doaj.org/article/fe11fb9eb1a34d309ffcfa360082b971
Autor:
Anastasia V Pavlova, Stella G Muthuri, Rachel Cooper, Fiona R Saunders, Jennifer S Gregory, Rebecca J Barr, Kathryn R Martin, Judith E Adams, Diana Kuh, Rebecca J Hardy, Richard M Aspden
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0197570 (2018)
This study investigated associations between measures of adiposity from age 36 and spine shape at 60-64 years. Thoracolumbar spine shape was characterised using statistical shape modelling on lateral dual-energy x-ray absorptiometry images of the spi
Externí odkaz:
https://doaj.org/article/fa23fdb565ed408987df758205e6b5e4
Autor:
Stella G. Muthuri, Anastasia V. Pavlova, Fiona R. Saunders, Rebecca J. Hardy, Jennifer S. Gregory, Rebecca J. Barr, Kathryn R. Martin, Judith E. Adams, Diana Kuh, Richard M. Aspden, Rachel Cooper
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract We aimed to examine whether back pain across adulthood was associated with spine shape at age 60–64 years. Data were from 1405 participants in the MRC National Survey of Health and Development, a nationally representative British birth coh
Externí odkaz:
https://doaj.org/article/c4e8db67720e4dfeaa7c48284873b70b
Autor:
Isla S Mackenzie, Christopher J Hawkey, Ian Ford, Nicola Greenlaw, Filippo Pigazzani, Amy Rogers, Allan D Struthers, Alan G Begg, Li Wei, Anthony J Avery, Jaspal S Taggar, Andrew Walker, Suzanne L Duce, Rebecca J Barr, Jennifer S Dumbleton, Evelien D Rooke, Jonathan N Townend, Lewis D Ritchie, Thomas M MacDonald, Husnat Ahmed, Peter Arthur, Jane Aziz, Lawrence Barnes, Sarah Boyle, Tom Brighton, Morris Brown, Mark Caulfield, Jesse Dawson, Martin Denvir, Alexander SF Doney, Sagar Doshi, Moira Dryburgh, Michael Eddleston, Jim Finlayson, Ahmet Fuat, Jacqueline Furnace, JW Kerr Grieve, Greg Guthrie, Sharon Ham, Emma Isaard, Claudine Jennings, Richard Johnson, Claire Kerr, Sohail Khan, Kailash Krishnan, Susan Long, Anne Mackintosh, Mary Joan Macleod, Terry McCormack, Paul McEleny, Monique Morar, Adnan Nadir, David Newby, Colin Petrie, David Preiss, Stuart Ralston, Marc Randall, Helen Routledge, Saad Shakir, Raj Sharma, Bridget Shepherd, Don Sims, Gordon Snedden, Jasper Trevelyan, Christopher Weir, Robin Weir, Kirsty Wetherall, Robbie Wilson, Adam Wilson, Kris Zutis
Publikováno v:
Lancet (London, England). 400(10359)
Allopurinol is a urate-lowering therapy used to treat patients with gout. Previous studies have shown that allopurinol has positive effects on several cardiovascular parameters. The ALL-HEART study aimed to determine whether allopurinol therapy impro
Autor:
Rebecca Hardy, Alex Ireland, Richard M. Aspden, Rachel Cooper, Pavlova Av, Jennifer S. Gregory, Stella G. Muthuri, Diana Kuh, Judith E. Adams, Fiona R. Saunders, Kathryn R. Martin, Rebecca J. Barr
Publikováno v:
Journal of Orthopaedic Research
Spine shape changes dramatically in early life, influenced by attainment of developmental milestones such as independent walking. Whether these associations persist across life is unknown. Therefore, we investigated associations between developmental
Autor:
K. Yoshida, Richard M. Aspden, Jennifer S. Gregory, Salvatore Alesci, Rebecca J. Barr, David M. Reid
Publikováno v:
Rheumatology. 59:2419-2426
Objectives Responsive biomarkers are needed to assess the progression of OA and their lack has hampered previous clinical trials. Statistical shape modelling (SSM) from radiographic images identifies those at greatest risk of fast-progression or join
Autor:
Amy Rogers, Isla S. Mackenzie, Angela Flynn, Thomas M. MacDonald, Robert W. V. Flynn, Alex S. F. Doney, Lewis McConnachie, Rebecca J. Barr
Publikováno v:
Pilot and feasibility studies. 8(1)
BackgroundObtaining evidence on comparative effectiveness and safety of widely prescribed drugs in a timely and cost-effective way is a major challenge for healthcare systems. Here we describe the feasibility of the Evaluating Diuretics in Normal Car
Autor:
Isla S. Mackenzie, Amy Rogers, Robert W. V. Flynn, Alex S. F. Doney, Angela Flynn, Lewis McConnachie, Rebecca J. Barr, Steve Morant, Thomas M. MacDonald
Publikováno v:
Trials
Trials, Vol 22, Iss 1, Pp 1-9 (2021)
Trials, Vol 22, Iss 1, Pp 1-9 (2021)
IntroductionHealthcare systems must use treatments that are effective and safe. Regulators licensed many currently used older medications before introducing the stringent evidential requirements imposed on modern treatments. Also, there has been litt
Publikováno v:
J Anat
The intrauterine environment is known to influence foetal development and future health. Low birthweight has been linked to smaller vertebral canals in children and decreased adulthood spine bone mineral content. Perinatal factors affecting lumbar sp
Autor:
Fiona R. Saunders, Scott Wilson, Benjamin H. Mullin, Claudiu V. Giuraniuc, Tim D. Spector, Frederick K. Kamanu, Douglas P. Kiel, Claes Ohlsson, Frances M K Williams, Deborah Jenkins, Denis Baird, Rebecca J. Barr, Nancy E Lane, Benjamin G. Faber, J. Brent Richards, Eric S. Orwoll, Elin Grundberg, Daniel Richard, Lavinia Paternoster, David M. Evans, Thomas J. Beck, Ulrika Pettersson-Kymmer, Jonathan H Tobias, Jennifer S. Gregory, David Karasik, Steven R. Cummings, Daniel S. Evans, Richard M. Aspden, Terence D. Capellini, Debbie A Lawlor
Publikováno v:
Journal of Bone and Mineral Research
Baird, D A, Evans, D S, Kamanu, F K, Gregory, J S, Saunders, F R, Giuraniuc, C V, Barr, R J, Aspden, R M, Jenkins, D, Kiel, D P, Orwoll, E S, Cummings, S R, Lane, N E, Mullin, B H, Williams, F M K, Richards, J B, Wilson, S G, Spector, T D, Faber, B G, Lawlor, D A, Grundberg, E, Ohlsson, C, Pettersson-Kymmer, U, Capellini, T D, Richard, D, Beck, T J, Evans, D M, Paternoster, L, Karasik, D & Tobias, J H 2018, ' Identification of Novel Loci Associated With Hip Shape : A Meta-Analysis of Genomewide Association Studies ', Journal of Bone and Mineral Research . https://doi.org/10.1002/jbmr.3605
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, vol 34, iss 2
Baird, DA; Evans, DS; Kamanu, FK; Gregory, JS; Saunders, FR; Giuraniuc, CV; et al.(2018). Identification of Novel Loci Associated With Hip Shape: A Meta-Analysis of Genomewide Association Studies. Journal of Bone and Mineral Research. doi: 10.1002/jbmr.3605. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/2tj6x8b6
Baird, D A, Evans, D S, Kamanu, F K, Gregory, J S, Saunders, F R, Giuraniuc, C V, Barr, R J, Aspden, R M, Jenkins, D, Kiel, D P, Orwoll, E S, Cummings, S R, Lane, N E, Mullin, B H, Williams, F M K, Richards, J B, Wilson, S G, Spector, T D, Faber, B G, Lawlor, D A, Grundberg, E, Ohlsson, C, Pettersson-Kymmer, U, Capellini, T D, Richard, D, Beck, T J, Evans, D M, Paternoster, L, Karasik, D & Tobias, J H 2018, ' Identification of Novel Loci Associated With Hip Shape : A Meta-Analysis of Genomewide Association Studies ', Journal of Bone and Mineral Research . https://doi.org/10.1002/jbmr.3605
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, vol 34, iss 2
Baird, DA; Evans, DS; Kamanu, FK; Gregory, JS; Saunders, FR; Giuraniuc, CV; et al.(2018). Identification of Novel Loci Associated With Hip Shape: A Meta-Analysis of Genomewide Association Studies. Journal of Bone and Mineral Research. doi: 10.1002/jbmr.3605. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/2tj6x8b6
© 2018 The Authors. Journal of Bone and Mineral Research Published by Wiley Periodicals, Inc. We aimed to report the first genomewide association study (GWAS) meta-analysis of dual-energy X-ray absorptiometry (DXA)-derived hip shape, which is though