Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rebecca J, Hertzman"'
Autor:
Elizabeth K. M. Johnstone, Mohammed Akli Ayoub, Rebecca J. Hertzman, Heng B. See, Rekhati S. Abhayawardana, Ruth M. Seeber, Kevin D. G. Pfleger
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The angiotensin type 2 (AT2) receptor and the bradykinin type 2 (B2) receptor are G protein-coupled receptors (GPCRs) that have major roles in the cardiovascular system. The two receptors are known to functionally interact at various levels, and ther
Externí odkaz:
https://doaj.org/article/05b7a90cfa2845508b41819310d3747e
Autor:
Rebecca J. Hertzman, Pooja Deshpande, Shay Leary, Yueran Li, Ramesh Ram, Abha Chopra, Don Cooper, Mark Watson, Amy M. Palubinsky, Simon Mallal, Andrew Gibson, Elizabeth J. Phillips
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Type B adverse drug reactions (ADRs) are iatrogenic immune-mediated syndromes with mechanistic etiologies that remain incompletely understood. Some of the most severe ADRs, including delayed drug hypersensitivity reactions, are T-cell mediated, restr
Externí odkaz:
https://doaj.org/article/6c81f4df17114a8389b04a92464deff3
Autor:
Yueran Li, Pooja Deshpande, Rebecca J. Hertzman, Amy M. Palubinsky, Andrew Gibson, Elizabeth J. Phillips
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Adverse drug reactions (ADRs) remain associated with significant mortality. Delayed hypersensitivity reactions (DHRs) that occur greater than 6 h following drug administration are T-cell mediated with many severe DHRs now associated with human leukoc
Externí odkaz:
https://doaj.org/article/06bc163f44164e2a8e9bda816c47c2c3
Autor:
Rebecca J. Hertzman, Pooja Deshpande, Katie D. White, Rama Gangula, Abha Chopra, Ramesh Ram, John A. Zic, Jeffrey P. Zwerner, Andrew Gibson, Elizabeth J. Phillips
Publikováno v:
J Dermatol Sci
Publikováno v:
Curr Opin Allergy Clin Immunol
Purpose of review An update of the pharmacogenetic risk factors associated with T-cell-mediated delayed hypersensitivity reactions. Recent findings Recent HLA associations relevant to our understanding of immunopathogenesis and clinical practice incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805d9a98902b0e5281a52c236c318aa1
https://europepmc.org/articles/PMC8243836/
https://europepmc.org/articles/PMC8243836/
Autor:
Pooja Deshpande, Amy M. Palubinsky, Jason B. Giles, Andrew Gibson, Rebecca J Hertzman, Elizabeth J. Phillips, Jason H. Karnes
Publikováno v:
Clin Pharmacol Ther
The human leukocyte antigen (HLA) system is the most polymorphic in the human genome that has been associated with protection and predisposition to a broad array of infectious, autoimmune, and malignant diseases. More recently over the last two decad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1f79d54a78d8ee8fa3fa3b2e6846ad
https://europepmc.org/articles/PMC8500648/
https://europepmc.org/articles/PMC8500648/
Autor:
Pooja Deshpande, Andrew Gibson, Elizabeth J. Phillips, Amy M. Palubinsky, Yueran Li, Rebecca J Hertzman
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics
Frontiers in Genetics
Adverse drug reactions (ADRs) remain associated with significant mortality. Delayed hypersensitivity reactions (DHRs) that occur greater than 6 h following drug administration are T-cell mediated with many severe DHRs now associated with human leukoc
Autor:
Abha Chopra, Elizabeth J. Phillips, John A. Zic, Andrew Gibson, Ramesh Ram, Rebecca J Hertzman, Shay Leary, Jeffrey P. Zwerner, Katie D. White, Rama Gangula, Pooja Deshpande
Publikováno v:
Journal of Allergy and Clinical Immunology. 147:AB31
Rationale Allergic contact dermatitis (ACD) is a classic delayed hypersensitivity reaction commonly associated with corticosteroids that can rarely manifest as a delayed rash following systemic administration. Methods A 50-year old woman developed lo