Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rebecca H. Herbst"'
Autor:
Amy Li, Rebecca H. Herbst, David Canner, Jason M. Schenkel, Olivia C. Smith, Jonathan Y. Kim, Michelle Hillman, Arjun Bhutkar, Michael S. Cuoco, C. Garrett Rappazzo, Patricia Rogers, Celeste Dang, Livnat Jerby-Arnon, Orit Rozenblatt-Rosen, Le Cong, Michael Birnbaum, Aviv Regev, Tyler Jacks
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 2998-3008.e8 (2019)
Summary: Regulatory T cells (Tregs) can impair anti-tumor immune responses and are associated with poor prognosis in multiple cancer types. Tregs in human tumors span diverse transcriptional states distinct from those of peripheral Tregs, but their c
Externí odkaz:
https://doaj.org/article/23e127cdd30c49738de5fb370ca4ae6d
Autor:
Rebecca H. Herbst, Dana Bar-Zvi, Sharon Reikhav, Ilya Soifer, Michal Breker, Ghil Jona, Eyal Shimoni, Maya Schuldiner, Avraham A. Levy, Naama Barkai
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-15 (2017)
Abstract Background The merging of genomes in inter-specific hybrids can result in novel phenotypes, including increased growth rate and biomass yield, a phenomenon known as heterosis. Heterosis is typically viewed as the opposite of hybrid incompati
Externí odkaz:
https://doaj.org/article/4447ca13ad1c4da0b7e4bcce267f9e83
Autor:
William L. Hwang, Megan L. Burger, Orit Rozenblatt-Rosen, Le Cong, Michael S. Cuoco, Tyler Jacks, Jonathan Y. Kim, David Canner, George Eng, Amy Li, Sean-Luc Shanahan, Peter M. K. Westcott, Olivia Smith, Patricia Rogers, Rebecca H. Herbst, Kristen E. Pauken, Grace Gibbons, Aviv Regev, Jason M. Schenkel, Jin K. Park, Michelle Hillman, William A. Freed-Pastor
Publikováno v:
Immunity
In tumors, a subset of CD8(+) T cells expressing the transcription factor TCF-1 drives the response to immune checkpoint blockade. We examined the mechanisms that maintain these cells in an autochthonous model of lung adenocarcinoma. Longitudinal sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4e9ed93c4fcd85dd5b84259ce61603
https://europepmc.org/articles/PMC8604155/
https://europepmc.org/articles/PMC8604155/
Autor:
Jonathan Y. Kim, Jason M. Schenkel, Jin K. Park, Tyler Jacks, Aviv Regev, Kristen E. Pauken, Peter M. K. Westcott, George Eng, Michelle Hillman, David Canner, Orit Rozenblatt-Rosen, William A. Freed-Pastor, Amy Li, Megan L. Burger, Patricia Rogers, Rebecca H. Herbst, Olivia Smith, Le Cong, William L. Hwang, Mike Cuoco
Publikováno v:
SSRN Electronic Journal.
During chronic antigen stimulation, CD8+ T cells lose their effector potential. Because much of our understanding of anti-tumor T cell dysfunction comes from shorter-term transplantable models, it is less clear how dysfunction shifts over time in tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48fbf97db005792cc78de27c7224507e
https://doi.org/10.2139/ssrn.3707275
https://doi.org/10.2139/ssrn.3707275
Autor:
Michal Breker, Ghil Jona, Maya Schuldiner, Eyal Shimoni, Sharon Reikhav, Ilya Soifer, Naama Barkai, Rebecca H. Herbst, Dana Bar-Zvi, Avraham A. Levy
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-15 (2017)
BMC Biology
BMC Biology
Background The merging of genomes in inter-specific hybrids can result in novel phenotypes, including increased growth rate and biomass yield, a phenomenon known as heterosis. Heterosis is typically viewed as the opposite of hybrid incompatibility. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c958c8cd35d529649cf3794705f9a85d
http://link.springer.com/article/10.1186/s12915-017-0373-7
http://link.springer.com/article/10.1186/s12915-017-0373-7
Autor:
Ashwin N. Ananthakrishnan, Orit Rozenblatt-Rosen, Jose Ordovas-Montanes, Sanja Vickovic, Matan Hofree, Lan T. Nguyen, Elizabeth A. Creasey, Malika Sud, Grace Burgin, Moshe Biton, Aviv Regev, Daniel B. Graham, Michal Slyper, Adam L. Haber, Julia Waldman, Mark J. Daly, Danielle Dionne, Garber Jj, Noga Rogel, Alexandra-Chloé Villani, Alex K. Shalek, Christopher Smillie, Desch An, Ramnik J. Xavier, Keri M. Sullivan, Rebecca H. Herbst, Hamed Khalili, Hongyan Huang, Elizabeth Andrews
Genome-wide association studies (GWAS) have revealed risk alleles for ulcerative colitis (UC), but their cell type and pathway specificities are often unknown. Here, we generate an atlas of 115,517 cells from the colon mucosa of seven UC patients and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0228cef9c4db32929ddd72e6f282b9
Autor:
Samantha J. Riesenfeld, Rebecca H. Herbst, Pavana Khan, Bruce D. Levy, Antonia Wallrapp, Aviv Regev, Conner Lambden, Patrick R. Burkett, Kazutake Tsujikawa, Alexandra Schnell, Pratiksha I. Thakore, Isaac M. Chiu, Kim Se-Jin, Vijay K. Kuchroo, Raja-Elie E. Abdulnour, Ramnik J. Xavier, Elena Christian
Publikováno v:
Prof. Regev via Courtney Crummett
Immunity
Immunity
Summary Neuroimmune interactions have emerged as critical modulators of allergic inflammation, and type 2 innate lymphoid cells (ILC2s) are an important cell type for mediating these interactions. Here, we show that ILC2s expressed both the neuropept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5405ee1be8a276e553ce7c1c3517c6
https://pubmed.ncbi.nlm.nih.gov/31618650
https://pubmed.ncbi.nlm.nih.gov/31618650
Autor:
Jonathan Y. Kim, Jason M. Schenkel, Celeste Dang, Rebecca H. Herbst, Michelle Hillman, Mike Cuoco, Orit Rozenblatt-Rosen, Aviv Regev, Rappazzo Cg, Le Cong, Aming Li, Michael E. Birnbaum, Tyler Jacks, Olivia Smith, Patricia Rogers, David Canner, Arjun Bhutkar
Regulatory T cells (Tregs) can impair anti-tumor immune responses and are associated with poor prognosis in multiple cancer types. Tregs in human tumors span diverse transcriptional states distinct from those of peripheral Tregs, but their contributi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef561699138c32c010dfa8603472e9e
Autor:
Orit Rozenblatt-Rosen, Jason M. Schenkel, Jonathan Y. Kim, Michael S. Cuoco, Tyler Jacks, Amy Li, C. Garrett Rappazzo, Michelle Hillman, David Canner, Rebecca H. Herbst, Arjun Bhutkar, Olivia Smith, Aviv Regev, Livnat Jerby-Arnon, Michael E. Birnbaum, Patricia Rogers, Celeste Dang, Le Cong
Publikováno v:
SSRN Electronic Journal.
Regulatory T cells (Tregs) can impair anti-tumor immune responses and are associated with poor prognosis in multiple cancer types. Tregs in human tumors span diverse transcriptional states distinct from those of peripheral Tregs, but their contributi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7635483c50e3aa1365bfce59d0fdc1c7
https://doi.org/10.2139/ssrn.3353223
https://doi.org/10.2139/ssrn.3353223
Autor:
Danielle Dionne, Lan Nguyen, Maria K. Lehtinen, Cristin McCabe, Samantha J. Riesenfeld, Christopher Rodman, Vitezslav Bryja, Jin Cui, Gilad Green, Jan Prochazka, Karol Kaiser, Orit Rozenblatt-Rosen, Aviv Regev, Neil Dani, Naomi Habib, Joshua P. Head, Ahram Jang, Michaela Prochazkova, Feng Zhang, Rebecca H. Herbst, Radislav Sedlacek, Frederick B. Shipley
Publikováno v:
Cell
The choroid plexus (ChP), located in each brain ventricle, produces cerebrospinal fluid (CSF) and forms the blood-CSF barrier, but is under-characterized. Here, we combine single cell RNA-Seq and spatial mapping of RNA and proteins to construct an at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8771940eae4ec082c7f401f736f60ab
https://doi.org/10.1016/j.cell.2021.04.003
https://doi.org/10.1016/j.cell.2021.04.003