Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Rebecca Guymon"'
Publikováno v:
Biochemistry. 45:4888-4899
Posttranscriptional modification in RNA generally serves to fine-tune and regulate RNA structure and, in many cases, is relatively conserved and phylogenetically distinct. We report the complete modification map for SSU rRNA from Thermus thermophilus
Publikováno v:
Nature Biotechnology. 23:232-237
Standard microarrays measure mRNA abundance, not mRNA synthesis, and therefore cannot identify the mechanisms that regulate gene expression. We have developed a method to overcome this limitation by using the salvage enzyme uracil phosphoribosyltrans
Autor:
Mark Del Campo, Claudia Recinos, Steven C. Pomerantz, James Ofengand, Giscard Yanez, Rebecca Guymon, James A. McCloskey, Pamela F. Crain
Publikováno v:
RNA. 11:210-219
The number and position of the pseudouridines of Haloarcula marismortui and Deinococcus radiodurans large subunit RNA have been determined by a combination of total nucleoside analysis by HPLC-mass spectrometry and pseudouridine sequencing by the rev
Autor:
Rebecca Guymon, Julianne Lim, James A. McCloskey, Michael Thomm, Pamela F. Crain, Ricardo Cavicchioli, Kathleen R. Noon
Publikováno v:
Journal of Bacteriology. 185:5483-5490
The posttranscriptional processing of tRNA produces a diverse wealth of modified nucleotides (29, 30, 41), most of which occur at conserved RNA sequence locations in all three phylogenetic domains (4, 45). Many of the functional roles of these modifi
Publikováno v:
Cell. 97:491-502
We report the crystal structure of a 58 nucleotide fragment of 23S ribosomal RNA bound to ribosomal protein L11. This highly conserved ribonucleoprotein domain is the target for the thiostrepton family of antibiotics that disrupt elongation factor fu
Post-transcriptional modifications of RNA are nearly ubiquitous in the principal RNAs involved in translation. However, in the case of rRNA the functional roles of modification are far less established than for tRNA, and are subject to less knowledge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef650f8b97ca9cafbf81b2a4b9b5418b
https://europepmc.org/articles/PMC1800508/
https://europepmc.org/articles/PMC1800508/
Autor:
Rebecca Guymon, James A. McCloskey, Steven C. Pomerantz, Vinod Nair, Tracy M. Wagner, Pamela F. Crain, Darrell R. Davis
Publikováno v:
Nucleic acids symposium series (2004). (48)
Sequence placement of post-transcriptionally modified nucleosides in tRNA can be experimentally difficult, particularly in cases involving new or unexpected modifications or sequence sites. We describe a mass spectrometry-based approach to this probl
Autor:
Shaolian Zhou, James A. McCloskey, Rebecca Guymon, Devarasetty Sitaramaiah, Kathleen R. Noon, Takeshi Hashizume
Publikováno v:
Bioorganic chemistry. 32(2)
The wyeosine (or wye) family of tricyclic ribonucleosides from archaeal and eukaryal tRNAPhe constitutes one of the most complex and interesting series of posttranscriptional RNA modifications, and has been the object of numerous studies of their che
Autor:
Kathleen R, Noon, Rebecca, Guymon, Pamela F, Crain, James A, McCloskey, Michael, Thomm, Julianne, Lim, Ricardo, Cavicchioli
Publikováno v:
Journal of bacteriology. 185(18)
We report the first study of tRNA modification in psychrotolerant archaea, specifically in the archaeon Methanococcoides burtonii grown at 4 and 23 degrees C. For comparison, unfractionated tRNA from the archaeal hyperthermophile Stetteria hydrogenop
Posttranscriptional modification of transfer RNA in the submarine hyperthermophile Pyrolobus fumarii
Autor:
Karl O. Stetter, Takeshi Hashizume, Eveline Bruenger, Xiao-Hui Liu, Pamela F. Crain, Rebecca Guymon, James A. McCloskey
Publikováno v:
Nucleic acids symposium series. (44)
In the RNA of hyperthermophiles, which grow optimally between 80 degrees C and 106 degrees C, posttranscriptional modification has been identified as a leading mechanism of structural stabilization. Particularly in the Archaeal evolutionary domain th