Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rebecca G, Zitnay"'
Autor:
Rebecca G Zitnay, Michael R Herron, Keith R Carney, Scott Potter, Lyska L Emerson, Jeffrey A Weiss, Michelle C Mendoza
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 10, p e1010153 (2022)
Early lung cancer lesions develop within a unique microenvironment that undergoes constant cyclic stretch from respiration. While tumor stiffening is an established driver of tumor progression, the contribution of stress and strain to lung cancer is
Externí odkaz:
https://doaj.org/article/ead9c3eff93c4d7e9bd85610e613f347
Autor:
Shiela C. Samson, Michelle C. Mendoza, Rediet Zewdu, Eric L. Snyder, Kelley Ingram, Rebecca G. Zitnay
Publikováno v:
Oncogene. 41:293-300
The RAS→RAF→MEK→ERK pathway is hyperactivated in the majority of human lung adenocarcinoma (LUAD). However, the initial activating mutations induce homeostatic feedback mechanisms that limit ERK activity. How ERK activation reaches the tumor-pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b642263384fad1cfacb91ff033150a05
https://doi.org/10.1038/s41388-021-02076-x
https://doi.org/10.1038/s41388-021-02076-x
Autor:
Rebecca G. Zitnay, Michael R. Herron, Keith R. Carney, Scott Potter, Lyska L. Emerson, Jeffrey A. Weiss, Michelle C. Mendoza
Early lung cancer lesions develop within a unique microenvironment that undergoes constant cyclic stretch from respiration. While tumor stiffening is an established driver of tumor progression, the contribution of stress and strain to lung cancer is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4dfe1f7a3bb5a9508ec086106fb3c38
https://doi.org/10.1101/2022.05.03.490386
https://doi.org/10.1101/2022.05.03.490386
The external environment is a regulator of cell activity. Its stiffness and microstructure can either facilitate or prevent 3D cell migration in both physiology and disease. 3D cell migration results from force feedbacks between the cell and the extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72519899fd6c793120cd029d384fe6df
https://doi.org/10.1101/2021.09.29.462287
https://doi.org/10.1101/2021.09.29.462287
Autor:
Kelley, Ingram, Shiela C, Samson, Rediet, Zewdu, Rebecca G, Zitnay, Eric L, Snyder, Michelle C, Mendoza
Publikováno v:
Oncogene. 41(2)
The RAS→RAF→MEK→ERK pathway is hyperactivated in the majority of human lung adenocarcinoma (LUAD). However, the initial activating mutations induce homeostatic feedback mechanisms that limit ERK activity. How ERK activation reaches the tumor-pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa9bdf4dbd211bec931ee05e4b9f1076
https://pubmed.ncbi.nlm.nih.gov/34689179
https://pubmed.ncbi.nlm.nih.gov/34689179