Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rebecca E. Schmitt"'
Autor:
Rebecca E. Schmitt, Aneesha Dasgupta, Paige C. Arneson‐Wissink, Srijani Datta, Alexandra M. Ducharme, Jason D. Doles
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 3, Pp 1424-1440 (2023)
Abstract Background Over the past decade, advances in sepsis identification and management have resulted in decreased sepsis mortality. This increase in survivorship has highlighted a new clinical obstacle: chronic critical illness (CCI), for which t
Externí odkaz:
https://doaj.org/article/f763139a496d4e0c8ec1783ce66e6e5c
Autor:
Daria Neyroud, Orlando Laitano, Aneesha Dasgupta, Christopher Lopez, Rebecca E. Schmitt, Jessica Z. Schneider, David W. Hammers, H. Lee Sweeney, Glenn A. Walter, Jason Doles, Sarah M. Judge, Andrew R. Judge
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Cancer-induced muscle wasting reduces quality of life, complicates or precludes cancer treatments, and predicts early mortality. Herein, we investigate the requirement of the muscle-specific E3 ubiquitin ligase, MuRF1, for muscle wasting ind
Externí odkaz:
https://doaj.org/article/325bfe808b054fee84c0ec177166dbea
Autor:
Rebecca E. Schmitt, Douglas Y. Smith, Dong Seong Cho, Lindsey A. Kirkeby, Zachary T. Resch, Teerin Liewluck, Zhiyv Niu, Margherita Milone, Jason D. Doles
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-17 (2022)
Abstract Hereditary muscle diseases are disabling disorders lacking effective treatments. UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE) myopathy (GNEM) is an autosomal recessive distal myopathy with rimmed vacuoles typically ma
Externí odkaz:
https://doaj.org/article/059ace6472c74dfba92e28f5719193eb
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 5, Pp 1351-1363 (2020)
Abstract Background Persistent loss of skeletal muscle mass and function as well as altered fat metabolism are frequently observed in severe sepsis survivors. Studies examining sepsis‐associated tissue dysfunction from the perspective of the tissue
Externí odkaz:
https://doaj.org/article/ee9c898a6d6344abad00dee7a294cebb
Autor:
Aneesha Dasgupta, Paige C. Arneson-Wissink, Rebecca E. Schmitt, Dong Seong Cho, Alexandra M. Ducharme, Tara L. Hogenson, Eugene W. Krueger, William R. Bamlet, Lizhi Zhang, Gina L. Razidlo, Martin E. Fernandez-Zapico, Jason D. Doles
Publikováno v:
JCI Insight, Vol 7, Iss 2 (2022)
Approximately 80% of pancreatic cancer patients suffer from cachexia, and one-third die due to cachexia-related complications such as respiratory failure and cardiac arrest. Although there has been considerable research into cachexia mechanisms and i
Externí odkaz:
https://doaj.org/article/fd3089a0330d47c2a75cc830a73c9afa
Publikováno v:
Shock (Augusta, Ga.). 58(1)
Sepsis is a highly prevalent cause of death in intensive care units. Characterized by severe immune cell derangements, sepsis is often associated with multiorgan dysfunction. For many sepsis survivors, these deficits can persist long after clinical r
Publikováno v:
Cancer Research. 83:356-356
Cancer cachexia is a multifactorial syndrome entailing muscle and fat wasting, inflammation, and metabolic dysfunction. Pancreatic cancer has the highest incidence of cachexia at around 80%. However, there are no FDA approved therapy for cachexia in
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 5, Pp 1351-1363 (2020)
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle
Background Persistent loss of skeletal muscle mass and function as well as altered fat metabolism are frequently observed in severe sepsis survivors. Studies examining sepsis‐associated tissue dysfunction from the perspective of the tissue microenv
Autor:
Zachary T. Resch, Teerin Liewluck, Margherita Milone, Jason D. Doles, Rebecca E. Schmitt, Lindsey A Kirkeby, Dong Seong Cho, Douglas Y Smith, Zhiyv Niu
Publikováno v:
NPJ Regenerative medicine. 7(1)
Hereditary muscle diseases are disabling disorders lacking effective treatments. UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE) myopathy is an autosomal recessive distal myopathy with rimmed vacuoles that typically manifests in
Autor:
Aneesha Dasgupta, Paige C. Arneson-Wissink, Rebecca E. Schmitt, Dong Seong Cho, Alexandra M. Ducharme, Tara L. Hogenson, Eugene W. Krueger, William R. Bamlet, Lizhi Zhang, Gina L. Razidlo, Martin E. Fernandez-Zapico, Jason D. Doles
Publikováno v:
JCI insight. 7(2)
Approximately 80% of pancreatic cancer patients suffer from cachexia, and one-third die due to cachexia-related complications such as respiratory failure and cardiac arrest. Although there has been considerable research into cachexia mechanisms and i