Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Rebecca E. Brown"'
Autor:
Rebecca E Brown, Xiaofeng A Su, Stacey Fair, Katherine Wu, Lauren Verra, Robyn Jong, Kristin Andrykovich, Catherine H Freudenreich
Publikováno v:
PLoS Biology, Vol 20, Iss 12, p e3001940 (2022)
Expansion of structure-forming CAG/CTG repetitive sequences is the cause of several neurodegenerative disorders and deletion of repeats is a potential therapeutic strategy. Transcription-associated mechanisms are known to cause CAG repeat instability
Externí odkaz:
https://doaj.org/article/4e5e87cf75114ffc87feeec5e2eda3e1
Autor:
Yogesh Tak, Silviya S Lal, Shilpa Gopan, Madhumitha Balakrishnan, Gouri Satheesh, Anup K Biswal, Amit K Verma, Sierra J Cole, Rebecca E Brown, Rachel E Hayward, Justin K Hines, Chandan Sahi
Publikováno v:
Journal of Experimental Botany. 74:1705-1722
J-domain proteins (JDPs) are critical components of the cellular protein quality control machinery, playing crucial roles in preventing the formation and, solubilization of cytotoxic protein aggregates. Bacteria, yeast, and plants additionally have l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593977b042ebc03a940c87d3129edfc8
https://doi.org/10.1093/jxb/erac514
https://doi.org/10.1093/jxb/erac514
Autor:
Amit K. Verma, Danish Diwan, Sandeep Raut, Neha Dobriyal, Rebecca E. Brown, Vinita Gowda, Justin K. Hines, Chandan Sahi
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 6, Pp 1941-1954 (2017)
Heat shock proteins of 70 kDa (Hsp70s) partner with structurally diverse Hsp40s (J proteins), generating distinct chaperone networks in various cellular compartments that perform myriad housekeeping and stress-associated functions in all organisms. P
Externí odkaz:
https://doaj.org/article/6f098355243d4f77b68e8fd0f709eb3f
Autor:
Rebecca E. Brown, Xiaofeng A. Su, Stacey Fair, Katherine Wu, Lauren Verra, Robyn Jong, Kristin Andrykovich, Catherine H. Freudenreich
Publikováno v:
PLoS biology. 20(12)
Expansion of structure-forming CAG/CTG repetitive sequences is the cause of several neurodegenerative disorders and deletion of repeats is a potential therapeutic strategy. Transcription-associated mechanisms are known to cause CAG repeat instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9afee7be703d25307eba247851977320
https://pubmed.ncbi.nlm.nih.gov/36574440
https://pubmed.ncbi.nlm.nih.gov/36574440
Autor:
Rebecca E. Brown, Xiaofeng A. Su, Stacey Fair, Katherine Wu, Lauren Verra, Robyn Jong, Kristin Andrykovich, Catherine H. Freudenreich
Expansion of structure-forming CAG/CTG repetitive sequences is the cause of several neurodegenerative disorders and deletion of repeats is a potential therapeutic strategy. Transcription-associated mechanisms are known to cause CAG repeat instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4738473bce4129783170e65c1daafc6
https://doi.org/10.1101/2021.12.06.471001
https://doi.org/10.1101/2021.12.06.471001
Autor:
David Jetton, Rebecca E. Brown, Machika Kaku, John M. Coffin, Daria Wells, John K Yoon, Joseph R Holloway
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
In vivo clonal expansion of HIV-infected T cells is an important mechanism of viral persistence. In some cases, clonal expansion is driven by HIV proviral DNA integrated into one of a handful of genes. To investigate this phenomenon in vitro, we infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9561dd9c9a9503d99c3ba23e8df273
https://doi.org/10.1073/pnas.2013194117
https://doi.org/10.1073/pnas.2013194117
Autor:
Justin K. Hines, Silviya S. Lal, Shilpa Gopan, Madhumitha Balakrishnan, Amit Kumar Verma, Yogesh Tak, Rachel E. Hayward, Rebecca E. Brown, Chandan Sahi, Sierra J. Cole
Hsp70s and J-domain proteins (JDPs) are among the most critical components of the cellular protein quality control machinery, playing crucial roles in preventing and solubilizing cytotoxic protein aggregates. Bacteria, yeast and plants additionally h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fec29242d5abb78a853de5f1c312248
https://doi.org/10.1101/2020.10.14.340331
https://doi.org/10.1101/2020.10.14.340331
Publikováno v:
Curr Opin Genet Dev
Repetitive sequences throughout the genome are a major source of endogenous DNA damage, due to the propensity of many of them to form alternative non-B DNA structures that can interfere with replication, transcription, and DNA repair. These repetitiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ad2f3064751cec73ada57803c6af1b
https://pubmed.ncbi.nlm.nih.gov/33279816
https://pubmed.ncbi.nlm.nih.gov/33279816
Autor:
Danish Diwan, Justin K. Hines, Rebecca E. Brown, Chandan Sahi, Sandeep Raut, Amit Kumar Verma, Vinita Gowda, Neha Dobriyal
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 6, Pp 1941-1954 (2017)
Heat shock proteins of 70 kDa (Hsp70s) partner with structurally diverse Hsp40s (J proteins), generating distinct chaperone networks in various cellular compartments that perform myriad housekeeping and stress-associated functions in all organisms. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54565bb154454436d74cff8670c0f409
https://doi.org/10.1534/g3.117.042291
https://doi.org/10.1534/g3.117.042291
Autor:
Justin K. Hines, Rebecca E. Brown
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e49ef51bc7ac22ffa026c4c904695b3
https://doi.org/10.1096/fasebj.2018.32.1_supplement.793.3
https://doi.org/10.1096/fasebj.2018.32.1_supplement.793.3