Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rebecca E Wagner"'
Autor:
Rebecca E. Wagner, Leonie Arnetzl, Thiago Britto-Borges, Anke Heit-Mondrzyk, Ali Bakr, Etienne Sollier, Nikoletta A. Gkatza, Jasper Panten, Sylvain Delaunay, Daniela Sohn, Peter Schmezer, Duncan T. Odom, Karin Müller-Decker, Christoph Plass, Christoph Dieterich, Pavlo Lutsik, Susanne Bornelöv, Michaela Frye
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114869- (2024)
Summary: The serine-/arginine-rich splicing factor 2 (SRSF2) plays pivotal roles in pre-mRNA processing and gene transcription. Recurrent mutations, particularly a proline-to-histidine substitution at position 95 (P95H), are common in neoplastic dise
Externí odkaz:
https://doaj.org/article/beaf20be6d8342c3b9a7f15e9370b6a4
Autor:
Jasper Panten, Tobias Heinen, Christina Ernst, Nils Eling, Rebecca E. Wagner, Maja Satorius, John C. Marioni, Oliver Stegle, Duncan T. Odom
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Cis-genetic effects are key determinants of transcriptional divergence in discrete tissues and cell types. However, how cis- and trans-effects act across continuous trajectories of cellular differentiation in vivo is poorly understood. Here,
Externí odkaz:
https://doaj.org/article/0aabafdc3a6a47a1b3c45ad1b7b7f851
Autor:
Roberto Bandiera, Rebecca E. Wagner, Thiago Britto-Borges, Christoph Dieterich, Sabine Dietmann, Susanne Bornelöv, Michaela Frye
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The noncoding RNA RN7SK regulates RNA polymerase II pausing and splicing. Here the authors deplete RN7SK in mouse and human during epidermal stem cell differentiation and reveal a novel role in orchestrating bidirectional transcription of highly expr
Externí odkaz:
https://doaj.org/article/934626f2ca0a4f63a03c33541d00ceca
Autor:
Abdulrahim A. Sajini, Nila Roy Choudhury, Rebecca E. Wagner, Susanne Bornelöv, Tommaso Selmi, Christos Spanos, Sabine Dietmann, Juri Rappsilber, Gracjan Michlewski, Michaela Frye
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
RNA modifications, including 5-methylcytosines, are known regulators of RNA metabolism affecting protein-RNA binding. Here, the authors reveal the role of m5C in the biogenesis of the non-coding vault-derived small RNAs.
Externí odkaz:
https://doaj.org/article/5f0b467423244eb692f642c3ff84eeee
Autor:
Martyna C. Popis, Rebecca E. Wagner, Fernando Constantino-Casas, Sandra Blanco, Michaela Frye
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-7 (2018)
Abstract Objective This study was designed to estimate the percentage of non-malignant skin tumours (papillomas) progressing to malignant squamous cell carcinomas (SCCs) in a carcinogenesis study using established transgenic mouse models. In our skin
Externí odkaz:
https://doaj.org/article/775bccc5a5b9406f9d7de59e66eccebb
Autor:
Christos Spanos, Susanne Bornelöv, Juri Rappsilber, Gracjan Michlewski, Sabine Dietmann, Abdulrahim A. Sajini, Tommaso Selmi, Michaela Frye, Nila Roy Choudhury, Rebecca E. Wagner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Sajini, A A, Roy Choudhury, N, Wagner, R E, Bornelöv, S, Selmi, T, Spanos, C, Dietmann, S, Rappsilber, J, Michlewski, G & Frye, M 2019, ' Loss of 5-methylcytosine alters the biogenesis of Vault-derived small RNAs to coordinate epidermal differentiation ', Nature Communications, vol. 10, 2550 . https://doi.org/10.1038/s41467-019-10020-7
Nature Communications
Sajini, A A, Roy Choudhury, N, Wagner, R E, Bornelöv, S, Selmi, T, Spanos, C, Dietmann, S, Rappsilber, J, Michlewski, G & Frye, M 2019, ' Loss of 5-methylcytosine alters the biogenesis of Vault-derived small RNAs to coordinate epidermal differentiation ', Nature Communications, vol. 10, 2550 . https://doi.org/10.1038/s41467-019-10020-7
The presence and absence of RNA modifications regulates RNA metabolism by modulating the binding of writer, reader, and eraser proteins. For 5-methylcytosine (m5C) however, it is largely unknown how it recruits or repels RNA-binding proteins. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ef5ab46dc27ee5914db5945f72ee5d
http://link.springer.com/article/10.1038/s41467-019-10020-7
http://link.springer.com/article/10.1038/s41467-019-10020-7
Autor:
Rebecca E Wagner, Michaela Frye
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biologyREFERENCES. 43(4)
Members of the serine/arginine (SR)-rich protein family of splicing factors play versatile roles in RNA processing steps and are often essential for normal development. Dynamic changes in RNA processing and turnover allow fast cellular adaptions to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c693de46f96c3893ff60235f7dd3223b
https://pubmed.ncbi.nlm.nih.gov/33554347
https://pubmed.ncbi.nlm.nih.gov/33554347
Autor:
Natalie Prior, Stefan A. Little, Cary Pirone, Julia E. Gill, Derek Smith, Jun Han, Darryl Hardie, Stephen J. B. O'Leary, Rebecca E. Wagner, Tyra Cross, Andrea Coulter, Christoph Borchers, Robert W. Olafson, Patrick von Aderkas
Publikováno v:
Applications in Plant Sciences, Vol 1, Iss 4, p 1300008 (2013)
Premise of the study: Pollination drops are a formative component in gymnosperm pollen-ovule interactions. Proteomics offers a direct method for the discovery of proteins associated with this early stage of sexual reproduction. Methods: Pollinatio
Externí odkaz:
https://doaj.org/article/08b30c1b6ff24533bf879403bd13ddf7
Autor:
Panten, Jasper, Heinen, Tobias, Ernst, Christina, Eling, Nils, Wagner, Rebecca E., Satorius, Maja, Marioni, John C., Stegle, Oliver, Odom, Duncan T.
Publikováno v:
Nature Communications; 2/10/2024, Vol. 15 Issue 1, p1-13, 13p
Autor:
Popis, Martyna C.1 mcp45@cam.ac.uk, Wagner, Rebecca E.2 rew55@cam.ac.uk, Constantino-Casas, Fernando3 fc307@cam.ac.uk, Blanco, Sandra4 sblanco@cicbiogune.es, Frye, Michaela1 amcp45@cam.ac.uk
Publikováno v:
BMC Research Notes. 1/24/2018, Vol. 11, p1-N.PAG. 7p. 1 Color Photograph, 1 Diagram, 1 Graph.