Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rebecca E Haddock"'
Autor:
Rebecca E Haddock, T Hilton Grayson, Margaret J Morris, Lauren Howitt, Preet S Chadha, Shaun L Sandow
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16423 (2011)
BACKGROUND: The vascular endothelium plays a critical role in the control of blood flow. Altered endothelium-mediated vasodilator and vasoconstrictor mechanisms underlie key aspects of cardiovascular disease, including those in obesity. Whilst the me
Externí odkaz:
https://doaj.org/article/a9d638c1b4b046f484809cf1f8d73354
Autor:
Caryl E. Hill, Rebecca E. Haddock
Publikováno v:
The Journal of Physiology. 589:3289-3307
Non-technical summary The maintenance of healthy blood pressure is influenced by the activity of the sympathetic perivascular nerves which surround small arteries and arterioles. Increases in sympathetic neurovascular control may play a role in the g
Autor:
Shaun L. Sandow, Caryl E. Hill, Donald G. Welsh, Paul M Kerr, Rebecca E. Haddock, Preet S. Chadha, Frances Plane
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 36:67-76
SUMMARY 1 Modulation of vascular cell calcium is critical for the control of vascular tone, blood flow and pressure. 2 Specialized microdomain signalling sites associated with calcium modulation are present in vascular smooth muscle cells, where spat
Abstract 18791: Immune Cell Derived Nerve Growth Factor Initiates Neurogenic Hypertension in Obesity
Autor:
Grant R Drummond, Klaus I Matthai, Susan K Morton, Antony Vinh, Dorota M Ferens, Juila I Ellyard, Carola G Vinuesa, Caryl E Hill, Rebecca E Haddock
Publikováno v:
Circulation. 132
Introduction: Hypertension in the obese is a rapidly increasing problem. It has both neurological and immunological antecedents, however the relationship between these is unclear. Methods and Results: Here we used a mouse model of diet-induced obesit
Autor:
Rebecca E. Haddock, Caryl E. Hill
Publikováno v:
The Journal of Physiology. 566:645-656
Many arteries and arterioles exhibit rhythmical contractions which are synchronous over considerable distances. This vasomotion is likely to assist in tissue perfusion especially during periods of altered metabolism or perfusion pressure. While the m
Autor:
Richard J.H. Wojcikiewicz, T. Hilton Grayson, Tracy P. Murray, Rebecca E. Haddock, Caryl E. Hill
Publikováno v:
Cell Calcium. 36:447-458
In blood vessels, the ability to control vascular tone depends on extracellular calcium entry and the release of calcium from inositol 1,4,5-trisphosphate receptor (IP3R)-gated stores located in both the endothelial and smooth muscle cells of the vas
Autor:
Rebecca E. Haddock, Caryl E. Hill
Publikováno v:
The Journal of Physiology. 545:615-627
Spontaneous, rhythmical contractions, or vasomotion, can be recorded from cerebral vessels under both normal physiological and pathophysiological conditions. Using electrophysiology to study changes in membrane potential, the ratiometric calcium indi
Publikováno v:
The Journal of Physiology. 540:219-229
The cellular mechanisms underlying vasomotion of irideal arterioles from juvenile rats have been studied using electrophysiological methods, ratiometric calcium measurements and video microscopy. Vasomotion was not affected by removal of the endothel
Autor:
Lauren Howitt, Russell D. Brown, Caryl E. Hill, Susan K. Morton, Rebecca E. Haddock, Klaus I. Matthaei, Daniel J. Chaston
Publikováno v:
Pflugers Archiv : European journal of physiology. 467(9)
Mutant forms of connexin40 (Cx40) exist in the human population and predispose carriers to atrial fibrillation. Since endothelial expression of Cx40 is important for electrical and chemical communication within the arterial wall, carriers of mutant C
Publikováno v:
The FASEB Journal. 28
Hypertension in obesity occurs as a result of abnormal increases in sympathetic nerve density over arteries controlling blood pressure; the causative factors underlying these changes are unknown. H...