Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Rebecca Dumbell"'
Autor:
Rebecca Dumbell, Roger D. Cox
Publikováno v:
Royal Society Open Science, Vol 11, Iss 2 (2024)
Externí odkaz:
https://doaj.org/article/f0fd438ec2f64577a1aaa4730a6b31d1
Autor:
Milan Mušo, Liz Bentley, Lucie Vizor, Marianne Yon, Keith Burling, Peter Barker, Louisa A. K. Zolkiewski, Roger D. Cox, Rebecca Dumbell
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Background: Increased waist-to-hip ratio (WHR) is associated with increased mortality and risk of type 2 diabetes and cardiovascular disease. The TBX15-WARS2 locus has consistently been associated with increased WHR. Previous study of the hypomorphic
Externí odkaz:
https://doaj.org/article/f7c60682630f43f89e23e3177f7a517a
Autor:
Haesung Yun, Rebecca Dumbell, Katie Hanna, Junior Bowen, Samantha L. McLean, Sriharsha Kantamneni, Klaus Pors, Qing-Feng Wu, Gisela Helfer
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Chemerin is an adipokine involved in inflammation, adipogenesis, angiogenesis and energy metabolism, and has been hypothesized as a link between obesity and type II diabetes. In humans affected by obesity, chemerin gene expression in peripheral tissu
Externí odkaz:
https://doaj.org/article/b2a1904a8b584a52a2c11d59036ef17a
Autor:
Lee Moir, Elena G. Bochukova, Rebecca Dumbell, Gareth Banks, Rasneer S. Bains, Patrick M. Nolan, Cheryl Scudamore, Michelle Simon, Kimberly A. Watson, Julia Keogh, Elana Henning, Audrey Hendricks, Stephen O'Rahilly, Inês Barroso, Adrienne E. Sullivan, David C. Bersten, Murray L. Whitelaw, Susan Kirsch, Elizabeth Bentley, I. Sadaf Farooqi, Roger D. Cox
Publikováno v:
Molecular Metabolism, Vol 6, Iss 11, Pp 1419-1428 (2017)
Objective: Genetic studies in obese rodents and humans can provide novel insights into the mechanisms involved in energy homeostasis. Methods: In this study, we genetically mapped the chromosomal region underlying the development of severe obesity in
Externí odkaz:
https://doaj.org/article/9e406993ddb94b1f857c7323c01dc9e0
Publikováno v:
International Journal of Endocrinology, Vol 2015 (2015)
Many physiological processes and most endocrine functions show fluctuations over the course of the day. These so-called circadian rhythms are governed by an endogenous network of cellular clocks and serve as an adaptation to daily and, thus, predicta
Externí odkaz:
https://doaj.org/article/0494f8857e17459e98b485f4007b3ad8
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90253 (2014)
The Siberian hamster (Phodopus sungorus) is a seasonal mammal responding to the annual cycle in photoperiod with anticipatory physiological adaptations. This includes a reduction in food intake and body weight during the autumn in anticipation of sea
Externí odkaz:
https://doaj.org/article/791ac822567c4772aed1230dcd094a04
Autor:
Milan, Mušo, Liz, Bentley, Lucie, Vizor, Marianne, Yon, Keith, Burling, Peter, Barker, Louisa A K, Zolkiewski, Roger D, Cox, Rebecca, Dumbell
Publikováno v:
Frontiers in physiology. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04c3bd973c37208fb4c1b8bfd2506aab
https://pubmed.ncbi.nlm.nih.gov/36091365
https://pubmed.ncbi.nlm.nih.gov/36091365
Autor:
Patrick M. Nolan, Gareth Banks, Nora Bourbia, Ashleigh G. Wilcox, Liz Bentley, Lee Moir, Lee Kent, Rosie Hillier, Dana Wilson, Perry Barrett, Rebecca Dumbell
A protein altering variant in the gene encoding zinc finger homeobox-3 (ZFHX3) has recently been associated with lower BMI in a human genome-wide association study. We investigated metabolic parameters in mice harbouring a missense mutation inZfhx3(Z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8512032ae3af8fbcb99a00ccef4a814
https://doi.org/10.1101/2022.05.25.493441
https://doi.org/10.1101/2022.05.25.493441
Autor:
George Powell, Helen Long, Louisa Zolkiewski, Rebecca Dumbell, Ann-Marie Mallon, Cecilia M. Lindgren, Michelle M. Simon
Understanding the genetic aetiology of loci associated with a disease is crucial for developing preventative measures and effective treatments. Mouse models are used extensively to understand human pathobiology and mechanistic functions of disease-as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf8e32c35f7c7a6c5945fec694fb502
https://irep.ntu.ac.uk/id/eprint/46011/1/1533815_Dumbell.pdf
https://irep.ntu.ac.uk/id/eprint/46011/1/1533815_Dumbell.pdf
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bbe40c71e12f163aa709867df141ff2
https://doi.org/10.1530/endoabs.77.op4.3
https://doi.org/10.1530/endoabs.77.op4.3