Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rebecca Deering Brose"'
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Down syndrome (DS), a genetic disorder caused by partial or complete triplication of chromosome 21, is the most common genetic cause of intellectual disability. DS mouse models and cell lines display defects in cellular adaptive stress responses incl
Externí odkaz:
https://doaj.org/article/4afa015220ff4a13aa5f59cad516a368
Autor:
Mark P. Mattson, Rebecca Deering Brose, Yongqing Zhang, Elin Lehrmann, Roger H. Reeves, Kirby D. Smith
Publikováno v:
Neurobiology of aging. 72
Alzheimer's disease (AD) is an age-related neurodegenerative disorder characterized by accumulation of amyloid β-peptide (Aβ) plaques in the brain and decreased cognitive function leading to dementia. We tested if hydroxyurea (HU), a ribonucleotide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b4eccde2d9b52a0ec925f6dfd131fe
https://pubmed.ncbi.nlm.nih.gov/30245242
https://pubmed.ncbi.nlm.nih.gov/30245242
Autor:
Gloria Shin, Kirby D. Smith, Shirley H. Purvis, Tonya Schneidereith, Gao X. Dong, Forrest Spencer, Rebecca Deering Brose, Jeffrey R. Keefer, Martina C. McGuinness
Publikováno v:
Human Molecular Genetics. 21:4237-4252
Various small molecule pharmacologic agents with different known functions produce similar outcomes in diverse Mendelian and complex disorders, suggesting that they may induce common cellular effects. These molecules include histone deacetylase inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a958442ff0b5f940ba9b6515c0a05a54
https://doi.org/10.1093/hmg/dds247
https://doi.org/10.1093/hmg/dds247
Publikováno v:
Journal of Neurology. 259:1440-1447
X-linked adrenoleukodystrophy (XALD), a neurological disorder caused by mutations in the peroxisomal membrane protein gene ABCD1, presents as a rapidly progressing, inflammatory cerebral demyelination (cerebral cases) or a slowly progressing, distal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d986bad1557711741d2a17406badcecd
https://doi.org/10.1007/s00415-011-6371-8
https://doi.org/10.1007/s00415-011-6371-8
Autor:
Rebecca Deering Brose, David J. Cutler, Aravinda Chakravarti, Teresa Lai, Barbara Coleman, Scott M. Blackman, Kathleen M. Naughton, Julie Hoover-Fong, Dan E. Arking, M. Daniele Fallin, Kristen West, Suzanne E. Beck, Garry R. Cutting, Ada Hamosh, Rita McWilliams, Marilyn Algire
Publikováno v:
Gastroenterology. 131:1030-1039
Background & Aims: Neonatal intestinal obstruction (meconium ileus [MI]) occurs in 15% of patients with cystic fibrosis (CF). Our aim was to determine the relative contribution of genetic and nongenetic modifiers to the development of this major comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6099ce632c1a63d1a2187de3be03ca5e
https://doi.org/10.1053/j.gastro.2006.07.016
https://doi.org/10.1053/j.gastro.2006.07.016