Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Rebecca D. Sandlin"'
Autor:
Justyna J. Jaskiewicz, Rebecca D. Sandlin, Anisa A. Swei, Giovanni Widmer, Mehmet Toner, Saul Tzipori
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Research on Cryptosporidium parasites, a major cause of acute infant diarrhea, is hampered by the short shelf life of oocysts, thus requiring routine propagation in laboratory animals. Here, the authors report a method to cryopreserve viable and infe
Externí odkaz:
https://doaj.org/article/29f50fe0cd184bbb9c8a46369b4ab7af
Autor:
Keith H. K. Wong, Shannon N. Tessier, David T. Miyamoto, Kathleen L. Miller, Lauren D. Bookstaver, Thomas R. Carey, Cleo J. Stannard, Vishal Thapar, Eric C. Tai, Kevin D. Vo, Erin S. Emmons, Haley M. Pleskow, Rebecca D. Sandlin, Lecia V. Sequist, David T. Ting, Daniel A. Haber, Shyamala Maheswaran, Shannon L. Stott, Mehmet Toner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
The current FDA-approved whole blood stabilization method for circulating tumor cell (CTC) isolation suffers from RNA degradation. Here the authors combine hypothermic preservation and antiplatelet strategies to stabilize whole blood up to 72 h witho
Externí odkaz:
https://doaj.org/article/2cb65508990f455f91b7d509541cd82f
Autor:
Rebecca D. Sandlin, Keith H. K. Wong, Leo Boneschansker, Thomas R. Carey, Kathleen L. Miller, Gregory Rose, Daniel A. Haber, Shyamala Maheswaran, Daniel Irimia, Shannon L. Stott, Mehmet Toner
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The deterioration of whole blood ex vivo represents a logistical hurdle in clinical and research settings. Here, a cocktail preservative is described that stabilizes leukocyte viability and erythrocyte morphology in whole blood under ambient
Externí odkaz:
https://doaj.org/article/c57942a3dc7846bba76a9debd6c2565f
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 5, Iss 3, Pp 84-91 (2015)
The Malaria Box, assembled by the Medicines for Malaria Venture, is a set of 400 structurally diverse, commercially available compounds with demonstrated activity against blood-stage Plasmodium falciparum. The compounds are a representative subset of
Externí odkaz:
https://doaj.org/article/82b28aad5c4b4cce9d0e4e34f22cc011
Autor:
Rebecca D. Sandlin, Kim Y. Fong, Kathryn J. Wicht, Holly M. Carrell, Timothy J. Egan, David W. Wright
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 4, Iss 3, Pp 316-325 (2014)
The emergence of drug resistant strains of Plasmodium spp. creates a critical need for the development of novel antimalarials. Formation of hemozoin, a crystalline heme detoxification process vital to parasite survival serves as an important drug tar
Externí odkaz:
https://doaj.org/article/5687d1b14efc4616a5dcb0fd0385e968
Autor:
Justyna J Jaskiewicz, Denise Ann E Dayao, Donald Girouard, Derin Sevenler, Giovanni Widmer, Mehmet Toner, Saul Tzipori, Rebecca D Sandlin
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011425 (2023)
Cryptosporidium hominis is a serious cause of childhood diarrhea in developing countries. The development of therapeutics is impeded by major technical roadblocks including lack of cryopreservation and simple culturing methods. This impacts the avail
Externí odkaz:
https://doaj.org/article/35d0be7bf04f4136abebfb3ec5d8f63d
Autor:
Derin Sevenler, Xin Niu, Sandy Dossantos, Mehmet Toner, Tim R. Cressey, Rebecca D. Sandlin, Paul K. Drain
Publikováno v:
J Antimicrob Chemother
Objectives Objective measurement of antiretrovirals may aid clinical interventions for improving adherence to HIV prevention or treatment regimens. A point-of-care urine test could provide real-time information about recent adherence to regimens cont
Autor:
Rebecca D Sandlin, Keith H K Wong, Shannon N Tessier, Anisa Swei, Lauren D Bookstaver, Bennett E Ahearn, Shyamala Maheswaran, Daniel A Haber, Shannon L Stott, Mehmet Toner
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192734 (2018)
Emerging technologies have enabled the isolation and characterization of rare circulating tumor cells (CTCs) from the blood of metastatic cancer patients. CTCs represent a non-invasive opportunity to gain information regarding the primary tumor and r
Externí odkaz:
https://doaj.org/article/e3bbc559b71a4af8a537a9235ab3fba2
Autor:
Justyna J. Jaskiewicz, Denise A.E. Dayao, Donald Girouard, Derin Sevenler, Giovanni Widmer, Mehmet Toner, Saul Tzipori, Rebecca D. Sandlin
Publikováno v:
Cryobiology. 109:43-44
Autor:
Anisa Swei, Mehmet Toner, Catherine M. Hunt, Ellen M. Dotson, Jenny E. Nesbitt, Rebecca D. Sandlin
Publikováno v:
Cryobiology. 99:106-113
Laboratory rearing of mosquitoes is commonly practiced by researchers studying mosquito-borne infectious diseases and vector control methods. In the absence of cryopreservation methods to stabilize unique or genetically modified strains, mosquito lin