Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rebecca D. Powell"'
Autor:
Arcadio Rubio García, Athina Paterou, Rebecca D. Powell Doherty, Laurie G. Landry, Mercede Lee, Amanda M. Anderson, Hubert Slawinski, Ricardo C. Ferreira, Dominik Trzupek, Agnieszka Szypowska, Linda S. Wicker, Luc Teyton, Nicola Ternette, Maki Nakayama, John A. Todd, Marcin L. Pekalski
Type 1 diabetes (T1D) is caused by a T-cell-mediated destruction of insulin-secreting pancreatic islet β cells. The T1D-predisposing human leukocyte antigen (HLA) class II molecule, DQ8, binds and presents insulin B chain peptides in the thymus prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::088d2857e527d780bc0ac671af83e408
https://doi.org/10.1101/2022.05.11.22274678
https://doi.org/10.1101/2022.05.11.22274678
Publikováno v:
The American Surgeon. 84:36-42
Conditions of systemic stress can lead to increased reactive oxygen species production, mitochondrial dysfunction, systemic inflammation, and multiorgan dysfunction. Triphenylphosphonium (TPP1) is a lipophilic cation used to target therapeutics to mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6c60cf75414136696b647db21b0e2a3
https://doi.org/10.1177/000313481808400119
https://doi.org/10.1177/000313481808400119
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Nora E. Raynor, Rebecca D. Powell-Doherty, David G. Jacobs, Anthony Stallion, Donna A. Goodenow
Publikováno v:
The American Journal of Surgery. 213:606-610
Diagnosing NAT (non-accidental trauma) includes a skeletal survey to identify injuries. A follow-up survey is performed for missed injuries. This study examines the necessity of follow-up surveys.The trauma database identified cases of suspected NAT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8658ff3f6f4f7fdd0b899a5c4d18525f
https://doi.org/10.1016/j.amjsurg.2016.12.004
https://doi.org/10.1016/j.amjsurg.2016.12.004
Publikováno v:
Journal of Trauma and Acute Care Surgery. 82:35-41
Background Hemorrhagic shock and reperfusion (HSR) injury leads to a cascade of reactive oxygen species (ROS) production and mitochondrial dysfunction, which results in energy failure, cell death, and multiple organ dysfunction. Cytochrome c (cyt c)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf77192afa93f1822f2bdaca7205ebcf
https://doi.org/10.1097/ta.0000000000001257
https://doi.org/10.1097/ta.0000000000001257
Publikováno v:
J Virol
Alzheimer’s Disease (AD) is the sixth leading cause of death in the United States. Recent studies have established a potential link between herpes simplex virus 1 (HSV-1) infection and the development of AD. HSV-1 DNA has been detected in AD amyloi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62f0e2b8919d98bc39c1536a2896272
https://pubmed.ncbi.nlm.nih.gov/32075924
https://pubmed.ncbi.nlm.nih.gov/32075924
Publikováno v:
The American surgeon. 84(1)
Conditions of systemic stress can lead to increased reactive oxygen species production, mitochondrial dysfunction, systemic inflammation, and multiorgan dysfunction. Triphenylphosphonium (TPP+) is a lipophilic cation used to target therapeutics to mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4df95edc0c710bdeaecf4a6665a0a36d
https://pubmed.ncbi.nlm.nih.gov/29428024
https://pubmed.ncbi.nlm.nih.gov/29428024
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Rebecca D. Powell, Jacob H. Swet, Iain H. McKillop, Kenneth L. Kennedy, Toan T. Huynh, Susan L. Evans
Publikováno v:
Journal of Trauma and Acute Care Surgery. 76:409-417
Background Oxidative stress following hemorrhagic shock and resuscitation (HSR) is regulated, in part, by inflammatory and apoptotic mediators such as necrosis factor κB (NF-κB) and p53. Sirtuin 1 (Sirt-1) is a metabolic intermediary that regulates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69b65a802bf2633e7313feb37640511
https://doi.org/10.1097/ta.0000000000000096
https://doi.org/10.1097/ta.0000000000000096
Publikováno v:
Journal of Biological Chemistry. 286:43596-43600
The SAMHD1 protein is an HIV-1 restriction factor that is targeted by the HIV-2 accessory protein Vpx in myeloid lineage cells. Mutations in the SAMHD1 gene cause Aicardi-Goutières syndrome, a genetic disease that mimics congenital viral infection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bafc73688fd4f1cf4961a7dc029a9b1
https://doi.org/10.1074/jbc.c111.317628
https://doi.org/10.1074/jbc.c111.317628