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pro vyhledávání: '"Rebecca D. Howell"'
Autor:
Rebecca D. Howell, Willard M. Freeman, Sergio Dominguez-Lopez, Michael J. Beckstead, Sarah R. Ocañas
Publikováno v:
Neurobiol Aging
SUMMARYThe degeneration of substantia nigra (SN) dopamine neurons is a central feature in the pathology associated with Parkinson’s disease, which is characterized by progressive loss of motor and cognitive functions. The largest risk factors for P
Publikováno v:
J Physiol
Key points Inhibition of synaptic responses by activation of presynaptic cannabinoid type-1 (Cb1) receptors is reduced at parallel fibre synapses in the cerebellum following 4 Hz stimulation. Activation of adenylyl cyclase is necessary and sufficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b6c9ab14d3bd319ba6dd62811c093a
https://europepmc.org/articles/PMC8128044/
https://europepmc.org/articles/PMC8128044/
Publikováno v:
The FASEB Journal. 33
Publikováno v:
The FASEB Journal. 33
Autor:
Jason R. Pugh, Rebecca D. Howell
Publikováno v:
The Journal of Physiology. 594:3651-3666
Key points Many excitatory synapses co-express presynaptic GABAA and GABAB receptors, despite their opposing actions on synaptic transmission. It is still unclear how co-activation of these receptors modulates synapse function. We measured presynapti