Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rebecca Clarke-Harris"'
Autor:
Karen Lillycrop, Robert Murray, Clara Cheong, Ai Ling Teh, Rebecca Clarke-Harris, Sheila Barton, Paula Costello, Emma Garratt, Eloise Cook, Philip Titcombe, Bhuvaneshwari Shunmuganathan, Samantha J. Liew, Yong-Cai Chua, Xinyi Lin, Yonghui Wu, Graham C. Burdge, Cyrus Cooper, Hazel M. Inskip, Neerja Karnani, James C. Hopkins, Caroline E. Childs, Carolina Paras Chavez, Philip C. Calder, Fabian Yap, Yung Seng Lee, Yap Seng Chong, Philip E. Melton, Lawrie Beilin, Rae-Chi Huang, Peter D. Gluckman, Nick Harvey, Mark A. Hanson, Joanna D. Holbrook, Keith M. Godfrey
Publikováno v:
EBioMedicine, Vol 19, Iss C, Pp 60-72 (2017)
Experimental studies show a substantial contribution of early life environment to obesity risk through epigenetic processes. We examined inter-individual DNA methylation differences in human birth tissues associated with child's adiposity. We identif
Externí odkaz:
https://doaj.org/article/b50df7b8db9e47929bab8c7d7eb822c2
Autor:
Samuel P Hoile, Rebecca Clarke-Harris, Rae-Chi Huang, Philip C Calder, Trevor A Mori, Lawrence J Beilin, Karen A Lillycrop, Graham C Burdge
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109896 (2014)
BACKGROUND: Studies in animal models and in cultured cells have shown that fatty acids can induce alterations in the DNA methylation of specific genes. There have been no studies of the effects of fatty acid supplementation on the epigenetic regulati
Externí odkaz:
https://doaj.org/article/ddf7ca4d96a74467b8edaf82bce9a49d
Autor:
Jeffrey M. Craig, Karen A. Lillycrop, Wendy H. Oddy, Rae-Chi Huang, Sebastian Rauschert, Graham C. Burdge, Phillip E. Melton, Rebecca Clarke-Harris, M A Burton, Keith M. Godfrey, J.L. MacIsaac, Craig E. Pennell, Denise Anderson, Alexander M. Morin, Lawrence J. Beilin, E Cook, J. D. Holbrook, Trevor A. Mori, Michael S. Kobor
Publikováno v:
Epigenetics
Epigenetics links perinatal influences with later obesity. We identifed differentially methylated CpG (dmCpG) loci measured at 17 years associated with concurrent adiposity measures and examined whether these were associated with hsCRP, adipokines, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c661517c10c3976ebdc5598a387638
https://doi.org/10.1080/15592294.2021.1876297
https://doi.org/10.1080/15592294.2021.1876297
Autor:
Philip C. Calder, Caroline E. Childs, Elizabeth A. Miles, Rebecca Clarke-Harris, Helena L. Fisk, Karen A. Lillycrop, Rob Ayres
Publikováno v:
Proceedings of the Nutrition Society. 79
Introduction:Obesity is an excess of adipose tissue (AT) and is linked with increased inflammation that enhances risk of type-2 diabetes and cardiovascular disease. The BIOCLAIMS study assessed the effect of obesity on AT fatty acid composition and g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2849b0e77fbacb2f72153f8126f8df3
https://doi.org/10.1017/s0029665120003134
https://doi.org/10.1017/s0029665120003134
Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthood
Autor:
Karen A, Lillycrop, Emma S, Garratt, Philip, Titcombe, Phillip E, Melton, Robert J S, Murray, Sheila J, Barton, Rebecca, Clarke-Harris, Paula M, Costello, Joanna D, Holbrook, James C, Hopkins, Caroline E, Childs, Carolina, Paras-Chavez, Philip C, Calder, Trevor A, Mori, Lawrie, Beilin, Graham C, Burdge, Peter D, Gluckman, Hazel M, Inskip, Nicholas C, Harvey, Mark A, Hanson, Rae-Chi, Huang, Cyrus, Cooper, Keith M, Godfrey
Publikováno v:
International Journal of Obesity (2005)
Background: The early life environment may influence susceptibility to obesity and metabolic disease in later life through epigenetic processes. SLC6A4 is an important mediator of serotonin bioavailability, and has a key role in energy balance. We te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5cb7277207d8ec2b2afb0c81c6996a22
https://eprints.soton.ac.uk/427537/
https://eprints.soton.ac.uk/427537/
Autor:
E. M. van der Beek, Cyrus Cooper, Allan Sheppard, Emma Garratt, P Costello, Hazel Inskip, Keith M. Godfrey, Sheila J. Barton, Graham C. Burdge, Elie Antoun, Sherry Ngo, T. Bhatt, Karen A. Lillycrop, Sarah El-Heis, Robert Murray, Rebecca Clarke-Harris
Publikováno v:
Clinical and Experimental Allergy, 47(12), 1599-1608. Wiley
Background There is now increasing evidence that asthma and atopy originate in part in utero, with disease risk being associated with the altered epigenetic regulation of genes. Objective and Methods To determine the relationship between variations i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7bf191bbfd7d771491a106b7b34526
https://research.rug.nl/en/publications/c68da4c0-8337-4e6f-b446-edb79029c2b1
https://research.rug.nl/en/publications/c68da4c0-8337-4e6f-b446-edb79029c2b1
Autor:
Brad S. Metcalf, Jonathan Pinkney, Linda D. Voss, Keith M. Godfrey, Terence J. Wilkin, Alison N. Jeffery, Graham C. Burdge, Karen A. Lillycrop, Joanne Hosking, Rebecca Clarke-Harris
Publikováno v:
Diabetes. 63:2528-2537
The early environment, acting via epigenetic processes, is associated with differential risk of cardiometabolic disease (CMD), which can be predicted by epigenetic marks in proxy tissues. However, such measurements at time points disparate from the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894fd182f8420134049d9fb5936630fe
https://doi.org/10.2337/db13-0671
https://doi.org/10.2337/db13-0671
Autor:
Robert Murray, Rebecca Clarke-Harris, E Cook, Karen A. Lillycrop, Elizabeth M Curtis, Keith M. Godfrey, Sheila J. Barton, Joanna D. Holbrook, Hazel Inskip, P Costello, Cyrus Cooper, Emma Garratt, Philip Titcombe, Nicholas C. Harvey
Publikováno v:
Rheumatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ccfb64b98645e4a17c07f71de08f883
https://doi.org/10.1093/rheumatology/kew102.002
https://doi.org/10.1093/rheumatology/kew102.002
Autor:
Graham C. Burdge, Trevor A. Mori, Samuel P. Hoile, Karen A. Lillycrop, Rebecca Clarke-Harris, Philip C. Calder, Rae-Chi Huang, Lawrence J. Beilin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 10, p e109896 (2014)
PLoS ONE, Vol 9, Iss 10, p e109896 (2014)
BACKGROUND: Studies in animal models and in cultured cells have shown that fatty acids can induce alterations in the DNA methylation of specific genes. There have been no studies of the effects of fatty acid supplementation on the epigenetic regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8514a2ab9cc720923f07becd89740e4
https://pubmed.ncbi.nlm.nih.gov/25329159
https://pubmed.ncbi.nlm.nih.gov/25329159
Autor:
Charlene M. Sibbons, Peter Lawrence, Graham C. Burdge, Karen A. Lillycrop, Rebecca Clarke-Harris, Samuel P. Hoile, J. Thomas Brenna
Publikováno v:
Prostaglandins, leukotrienes, and essential fatty acids. 90(2-3)
Female humans and rodents have been shown to have higher 22:6n-3 status than males. Sex hormones are involved, but it is unclear whether higher 22:6n-3 status and biosynthesis in females is mediated by the action of estrogen or progesterone. We inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c252b7fa9a950261a6cc029da02f1fed
https://pubmed.ncbi.nlm.nih.gov/24411721
https://pubmed.ncbi.nlm.nih.gov/24411721