Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rebecca Claire Greenwood"'
Autor:
William H. Miller, Catherine C.K. Yuan, Kalindi Vaidya, Brian J. Polizzi, Dennis T. Takata, Rebecca Claire Greenwood, Dirk A. Heerding, Mark A. Seefeld, Scott B. Winram, Valerie Berry, Martha S. Head, Walter J. Burgess, Andrew P. Fosberry, Nicola G. Wallis, David J. Payne, Stephen Rittenhouse, William F. Huffman, Paul M. Keller, Kevin L. Salyers, Manley Peter J, Kenneth A. Newlander, Deborah Dee Jaworski, Courtney Slater-Radosti, Cheryl A. Janson, Walter E. DeWolf, Irene N. Uzinskas, John Brosky, Stewart C. Pearson, Xiayang Qiu, Emile Chen, Terrance D. Moore, Martin G. Smyth
Publikováno v:
Antimicrobial Agents and Chemotherapy. 46:3118-3124
Bacterial enoyl-acyl carrier protein (ACP) reductase (FabI) catalyzes the final step in each elongation cycle of bacterial fatty acid biosynthesis and is an attractive target for the development of new antibacterial agents. High-throughput screening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997a68e3d46cb5b0dd9196003827969e
https://doi.org/10.1128/aac.46.10.3118-3124.2002
https://doi.org/10.1128/aac.46.10.3118-3124.2002
Publikováno v:
The Journal of Antibiotics. 55:423-426
The compound designated SB-219383 is a potent and selective inhibitor of bacterial tyrosyl tRNA synthetases. It exhibits an IC50 of < 1 nM against Staphylococcus aureus tyrosyl tRNA synthetase and weak in vitro activity against Staphylococci and Stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aad4b70cb3bad461d3b44fc07ab2c74
https://doi.org/10.7164/antibiotics.55.423
https://doi.org/10.7164/antibiotics.55.423
Autor:
Paul M. Keller, Deborah Dee Jaworski, Frank Fan, Courtney Slater-Radosti, Richard O. Nicholas, Walter E. DeWolf, Glenn S. Van Aller, Rebecca Claire Greenwood, David J. Payne
Publikováno v:
Journal of Antimicrobial Chemotherapy. 48:1-6
Triclosan, a widely used antibacterial agent, possesses potent activity against Staphylococcus aureus. This study reports on an investigation of the antibacterial target of triclosan in this pathogen. A strain of S. aureus overexpressing the enoyl-[a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450b33a07c2564b7cecb1f43211c4d7c
https://doi.org/10.1093/jac/48.1.1
https://doi.org/10.1093/jac/48.1.1
Publikováno v:
FEMS microbiology letters. 208(2)
In an assessment of antibiotic action on Staphylococcus aureus, we found that distinct changes in intracellular nucleotide pools occur depending on the antibiotic mode of action. In particular, we have quantitated the effect of antibiotics on pools o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3574375c9072019aaa3ad7499e9d5152
https://pubmed.ncbi.nlm.nih.gov/11959437
https://pubmed.ncbi.nlm.nih.gov/11959437