Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rebecca C. Feiner"'
Autor:
Hendrik Gruß, Rebecca C. Feiner, Ridhiwan Mseya, David C. Schröder, Michał Jewgiński, Kristian M. Müller, Rafał Latajka, Antoine Marion, Norbert Sewald
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 18, Iss 1, Pp 1-12 (2022)
The development of peptide stapling techniques to stabilise α-helical secondary structure motifs of peptides led to the design of modulators of protein–protein interactions, which had been considered undruggable for a long time. We disclose a nove
Externí odkaz:
https://doaj.org/article/b1e73b21829c4343991dd07924fa3253
Autor:
Rebecca C. Feiner, David C. Schröder, Antoine Marion, Norbert Sewald, Isabell Kemker, Kristian M. Müller
Publikováno v:
Journal of Medicinal Chemistry. 64:586-601
An array of l- and d-halotryptophans with different substituents at the indole moiety was synthesized employing either enzymatic halogenation by halogenases or incorporation of haloindoles using tryptophan synthase. Introduction of these Trp derivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1771d700ac252daab0af281815a9e64
https://doi.org/10.1021/acs.jmedchem.0c01536
https://doi.org/10.1021/acs.jmedchem.0c01536
Publikováno v:
Biochemistry. 58:1043-1047
The epidermal growth factor receptor (EGFR) is a transmembrane protein involved in cell signaling processes, and dysregulation of its activity often drives tumor growth. EGFR is a clinically validated tumor marker and target for antibodies and tyrosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0804907244f0d4a06e03b23bd189fc9a
https://doi.org/10.1021/acs.biochem.9b00021
https://doi.org/10.1021/acs.biochem.9b00021
Autor:
Christian Schnepel, Hannah Minges, Rebecca C. Feiner, Marcel Frese, Hauke Voss, Norbert Sewald
Publikováno v:
ChemInform. 47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8302aff6f79e774b34172facb9f7a65a
https://doi.org/10.1002/chin.201641074
https://doi.org/10.1002/chin.201641074
Autor:
Rebecca C. Feiner, Kristian M. Müller
Introduction: Epidermal growth factor receptor (EGFR) expression is upregulated in many tumors and its aberrant signaling drives progression of many cancer types. Consequently, EGFR has become a clinically validated target as extracellular tumor mark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fbad7540c4109795954b5a1e3a4783b
https://doi.org/10.1080/14789450.2016.1212665
https://doi.org/10.1080/14789450.2016.1212665
Autor:
Marcel Frese, Christian Schnepel, Hannah Minges, Norbert Sewald, Hauke Voß, Rebecca C. Feiner
The combination of the biocatalytic halogenation of l-tryptophan with subsequent chemocatalytic Suzuki-Miyaura crosscoupling reactions leads to the modular synthesis of an array of C5, C6, or C7 aryl-substituted tryptophan derivatives. In a three-ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f48dcf2b73e5bd71803e286137562e
https://pub.uni-bielefeld.de/record/2905164
https://pub.uni-bielefeld.de/record/2905164
Autor:
Hannah Minges, Christian Schnepel, Hauke Voß, Marcel Frese, Rebecca C. Feiner, Norbert Sewald
Publikováno v:
ChemCatChem. 8:1749-1749
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8238decab74b4e9198f5d36109cf1154
https://doi.org/10.1002/cctc.201600526
https://doi.org/10.1002/cctc.201600526