Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rebecca C Haycox"'
Autor:
Paul M. Neilsen, David F. Callen, Jayesh Desai, David M. Thomas, Andreas Evdokiou, Richard J. D'Andrea, Michael P. Brown, Kristen Ho, Rebecca C. Haycox, Bronwen J. Mayo, Steve Chryssidis, Jim Manavis, Gelareh Farshid, Robert J. Whitfield, Michelle Perugini, David M. Lawrence, Andreas W. Schreiber, Mark T. Clayer, Susan J. Neuhaus, Kathleen I. Pishas
PDF file - 67K, TP53 pathway alterations do not mediate sarcoma cytostatic response to Nutlin-3a.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d47db383105720a35f84cd1d3813e03
https://doi.org/10.1158/0008-5472.22402151
https://doi.org/10.1158/0008-5472.22402151
Autor:
Paul M. Neilsen, David F. Callen, Jayesh Desai, David M. Thomas, Andreas Evdokiou, Richard J. D'Andrea, Michael P. Brown, Kristen Ho, Rebecca C. Haycox, Bronwen J. Mayo, Steve Chryssidis, Jim Manavis, Gelareh Farshid, Robert J. Whitfield, Michelle Perugini, David M. Lawrence, Andreas W. Schreiber, Mark T. Clayer, Susan J. Neuhaus, Kathleen I. Pishas
PDF file - 44K, Comparison of sequencing facilities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01aa481b46848ee0c6e2385133cfc715
https://doi.org/10.1158/0008-5472.22402157
https://doi.org/10.1158/0008-5472.22402157
Autor:
Paul M. Neilsen, David F. Callen, Jayesh Desai, David M. Thomas, Andreas Evdokiou, Richard J. D'Andrea, Michael P. Brown, Kristen Ho, Rebecca C. Haycox, Bronwen J. Mayo, Steve Chryssidis, Jim Manavis, Gelareh Farshid, Robert J. Whitfield, Michelle Perugini, David M. Lawrence, Andreas W. Schreiber, Mark T. Clayer, Susan J. Neuhaus, Kathleen I. Pishas
PDF file - 58K, GADD45A and sarcoma pathology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5c0d99e7fff6c3464fe7f0a185616e
https://doi.org/10.1158/0008-5472.22402145
https://doi.org/10.1158/0008-5472.22402145
Autor:
Paul M. Neilsen, David F. Callen, Jayesh Desai, David M. Thomas, Andreas Evdokiou, Richard J. D'Andrea, Michael P. Brown, Kristen Ho, Rebecca C. Haycox, Bronwen J. Mayo, Steve Chryssidis, Jim Manavis, Gelareh Farshid, Robert J. Whitfield, Michelle Perugini, David M. Lawrence, Andreas W. Schreiber, Mark T. Clayer, Susan J. Neuhaus, Kathleen I. Pishas
PDF file - 178K, Nutlin-3a induces cytostatic responses in sarcoma patient material.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de7e4a28d5e3c5d15cded89d8e341fd
https://doi.org/10.1158/0008-5472.22402154
https://doi.org/10.1158/0008-5472.22402154
Autor:
Paul M. Neilsen, David F. Callen, Jayesh Desai, David M. Thomas, Andreas Evdokiou, Richard J. D'Andrea, Michael P. Brown, Kristen Ho, Rebecca C. Haycox, Bronwen J. Mayo, Steve Chryssidis, Jim Manavis, Gelareh Farshid, Robert J. Whitfield, Michelle Perugini, David M. Lawrence, Andreas W. Schreiber, Mark T. Clayer, Susan J. Neuhaus, Kathleen I. Pishas
PDF file - 43K, Induction of GADD45A and BBC3 is associated with Nutlin-3a induced apoptosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ec3d3b46308997a918cad40f226121
https://doi.org/10.1158/0008-5472.22402148
https://doi.org/10.1158/0008-5472.22402148
Autor:
Paul M. Neilsen, David F. Callen, Jayesh Desai, David M. Thomas, Andreas Evdokiou, Richard J. D'Andrea, Michael P. Brown, Kristen Ho, Rebecca C. Haycox, Bronwen J. Mayo, Steve Chryssidis, Jim Manavis, Gelareh Farshid, Robert J. Whitfield, Michelle Perugini, David M. Lawrence, Andreas W. Schreiber, Mark T. Clayer, Susan J. Neuhaus, Kathleen I. Pishas
Nutlin-3a is a small-molecule antagonist of p53/MDM2 that is being explored as a treatment for sarcoma. In this study, we examined the molecular mechanisms underlying the sensitivity of sarcomas to Nutlin-3a. In an ex vivo tissue explant system, we f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72a619a2361e24cadf4dada0aa8017b5
https://doi.org/10.1158/0008-5472.c.6505997
https://doi.org/10.1158/0008-5472.c.6505997
Autor:
Robert J. Whitfield, Jayesh Desai, Michael P. Brown, Paul M. Neilsen, Gelareh Farshid, Andreas W. Schreiber, David F. Callen, Jim Manavis, Kathleen I. Pishas, Andreas Evdokiou, Michelle Perugini, Mark Clayer, David M. Lawrence, Susan J. Neuhaus, Rebecca C Haycox, Bronwen J. Mayo, Steve Chryssidis, Kristen Ho, David Thomas, Richard J D'Andrea
Publikováno v:
Cancer Research. 74:921-931
Nutlin-3a is a small-molecule antagonist of p53/MDM2 that is being explored as a treatment for sarcoma. In this study, we examined the molecular mechanisms underlying the sensitivity of sarcomas to Nutlin-3a. In an ex vivo tissue explant system, we f