Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Rebecca C Allsopp"'
Autor:
Rebecca C Allsopp, Caroline M Cowley, Ruth C Barber, Carolyn Jones, Christopher W Holmes, Paul W Bird, Shailesh G Gohil, Claire Blackmore, Martin D Tobin, Nigel Brunskill, Philip N Baker, Jacqui A Shaw
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0273912 (2022)
PurposeTo demonstrate the diagnostic performance of rapid SARS-CoV-2 RT-LAMP assays, comparing the performance of genomic versus sub-genomic sequence target with subsequent application in an asymptomatic screening population.MethodsRT-LAMP diagnostic
Externí odkaz:
https://doaj.org/article/5cd4c4f3e2524e02a11cdb6fd177236a
Autor:
Claire Blackmore, Gareth W. Hall, Rebecca C. Allsopp, Anna L. Hansell, Caroline M. Cowley, Ruth C. Barber, Christopher W. Holmes, Martin D. Tobin, Jacqui A. Shaw, Nigel J. Brunskill, Philip N. Baker
Publikováno v:
BMC Health Services Research, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Little is known about how asymptomatic testing as a method to control transmission of COVID-19 can be implemented, and the prevalence of asymptomatic infection within university populations. The objective of this study was to inve
Externí odkaz:
https://doaj.org/article/f2ed7dc06b9f48ccb6d7619f59cf478c
Autor:
Rebecca C Allsopp, Karen Page, Bana Ambasager, Marc K Wadsley, Emmanuel Acheampong, Tumisang P Ntereke, Qi Guo, Gurdeep Matharu Lall, Kelly L T Gleason, Evie Wren, Georgios Nteliopoulos, Amelia J Rushton, R Charles Coombes, Jacqueline A Shaw
Publikováno v:
Clinical Chemistry. 69:510-518
Background Somatic copy number alterations (sCNAs) acquired during the evolution of breast cancer provide valuable prognostic and therapeutic information. Here we present a workflow for screening sCNAs using picogram amounts of cell-free DNA (cfDNA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e944b78ecb25a6e2ffa9168bd02f9cf
https://doi.org/10.1093/clinchem/hvac220
https://doi.org/10.1093/clinchem/hvac220
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The P2X7 receptor (P2X7R) for ATP is a therapeutic target for pathophysiological states including inflammation, pain management and epilepsy. This is facilitated by the predicted low side effect profile as the high concentrations of ATP requ
Externí odkaz:
https://doaj.org/article/e4b325c9e8ca423abe4e714e25c558a0
Autor:
Alison Harrod, Chun-Fui Lai, Isabella Goldsbrough, Georgia M. Simmons, Natasha Oppermans, Daniela B. Santos, Balazs Győrffy, Rebecca C. Allsopp, Bradley J. Toghill, Kirsty Balachandran, Mandy Lawson, Christopher J. Morrow, Manasa Surakala, Larissa S. Carnevalli, Pei Zhang, David S. Guttery, Jacqueline A. Shaw, R. Charles Coombes, Lakjaya Buluwela, Simak Ali
Mutations in the estrogen receptor (ESR1) gene are common in ER-positive breast cancer patients who progress on endocrine therapies. Most mutations localise to just three residues at, or near, the C-terminal helix 12 of the hormone binding domain, at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ed4c121c9a2b1ba06f783118487549
http://hdl.handle.net/10044/1/99787
http://hdl.handle.net/10044/1/99787
Autor:
Daniel Fernandez-Garcia, Georgios Nteliopoulos, Robert K. Hastings, Amelia Rushton, Karen Page, Rebecca C. Allsopp, Bana Ambasager, Kelly Gleason, David S. Guttery, Simak Ali, R. Charles Coombes, Jacqueline A. Shaw
Background We report copy-number profiling by low-pass WGS (LP-WGS) in individual circulating tumour cells (CTCs) for guiding treatment in patients with metastatic breast cancer (MBC), comparing CTC results with mutations detected in circulating tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28aacb0394a50d977ec35f4a905a3269
http://hdl.handle.net/10044/1/101969
http://hdl.handle.net/10044/1/101969
Autor:
Kenny Malpartida-Cardenas, Simak Ali, Pantelis Georgiou, R. Charles Coombes, Ling-Shan Yu, George Alexandrou, Christofer Toumazou, Kelly L. T. Gleason, Karen Page, Rebecca C. Allsopp, Nicholas Miscourides, Jacqueline A Shaw, Jesus Rodriguez-Manzano, K. Goddard, Daniel Fernandez-Garcia, Melpomeni Kalofonou
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Breast cancer (BC) is a common cancer in women worldwide. Despite advances in treatment, up to 30% of women eventually relapse and die of metastatic breast cancer. Liquid biopsy analysis of circulating cell-free DNA fragments in the patients’ blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17946e4df33a47cf63eb55bdc729df1f
http://link.springer.com/article/10.1038/s41598-020-60852-3
http://link.springer.com/article/10.1038/s41598-020-60852-3
Autor:
Nigel J. Brunskill, Martin D. Tobin, Christopher Holmes, Philip N. Baker, Claire Blackmore, Paul W Bird, Jacqui Shaw, Rebecca C. Allsopp, Shailesh Gohil, Carolyn J.P. Jones, Caroline Cowley, Ruth C. Barber
This study demonstrates the diagnostic performance of SARS-CoV-2 RT-LAMP assays, comparing the performance of genomic versus sub-genomic sequence target with subsequent application in an asymptomatic screening population. An RT-LAMP workflow was deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f83484774a9faeab81469ef2a04f977
https://doi.org/10.21203/rs.3.rs-847286/v1
https://doi.org/10.21203/rs.3.rs-847286/v1
Autor:
Christopher W Holmes, Nigel J. Brunskill, Ruth C. Barber, Martin D. Tobin, Gareth Hall, Rebecca C. Allsopp, Caroline M. Cowley, Claire Blackmore, Anna Hansell, Jacqui Shaw, Philip N. Baker
Publikováno v:
SSRN Electronic Journal.
Background: Little is known about how asymptomatic testing as a method to control transmission of COVID-19 can be implemented, and the prevalence of asymptomatic infection within university populations. This study is the first to report prevalence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69095d178898b3c9175b6c69908d4845
https://doi.org/10.2139/ssrn.3945447
https://doi.org/10.2139/ssrn.3945447
Publikováno v:
Molecular Pharmacology
P2X7 receptor (P2X7R) activation requires ∼100-fold higher concentrations of ATP than other P2X receptor (P2XR) subtypes. Such high levels are found during cellular stress, and P2X7Rs consequently contribute to a range of pathophysiological conditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b8265743a39033c25604e365e5c1ce
https://pubmed.ncbi.nlm.nih.gov/29535152
https://pubmed.ncbi.nlm.nih.gov/29535152