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pro vyhledávání: '"Rebecca Boohaker"'
Autor:
John K. Cini, Richard T. Kenney, Susan Dexter, Stephen J. McAndrew, Rukiye-Nazan Eraslan, Rich Brody, Darrel J. Rezac, Rebecca Boohaker, Suzanne E. Lapi, Pankaj Mohan
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundCytokines have been promising cancer immunotherapeutics for decades, yet only two are licensed to date. Interleukin-12 (IL-12) is a potent regulator of cell-mediated immunity that activates NK cells and interferon-γ (IFNγ) production. It
Externí odkaz:
https://doaj.org/article/438bbbcb4fa04e72a0a4640f320246d0
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract The alpha-fetoprotein receptor (AFPR) is a novel target for cancer therapeutics. It is expressed on most cancers and myeloid derived suppressor cells (MDSCs) but generally absent on normal tissues. Studies were performed to investigate the u
Externí odkaz:
https://doaj.org/article/180652f27b284797942f48e069c54fd1
Publikováno v:
The Journal of Immunology. 182:35.12-35.12
Apoptosis is a complex process essential for cellular homeostasis. Early physiological changes that initiate cell death remain poorly understood. Previously, we observed that lymphocytes, undergoing apoptosis in response to loss of a growth factor ex