Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rebecca Albano"'
Autor:
Matthew C. Garrett, Rebecca Albano, Troy Carnwath, Lubayna Elahi, Catherine A. Behrmann, Merissa Pemberton, Daniel Woo, Eric O’Brien, Brett VanCauwenbergh, John Perentesis, Sanjit Shah, Matthew Hagan, Ady Kendler, Chuntao Zhao, Aditi Paranjpe, Krishna Roskin, Harley Kornblum, David R. Plas, Q. Richard Lu
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Low-grade and secondary high-grade gliomas frequently contain mutations in the IDH1 or IDH2 metabolic enzymes that are hypothesized to drive tumorigenesis by inhibiting many of the chromatin-regulating enzymes that regulate DNA structure. Hi
Externí odkaz:
https://doaj.org/article/cd41171c4c2c402c887577588bb94c39
Autor:
Matthew C. Garrett, Rebecca Albano, Troy Carnwath, Sanjit Shah, Daniel Woo, Michael Lamba, David R. Plas, Aditi Paranjpe, Krishna Roskin, Chuntao Zhao, Richard Lu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The pathological changes in epigenetics and gene regulation that accompany the progression of low-grade to high-grade gliomas are under-studied. The authors use a large set of paired atac-seq and RNA-seq data from surgically resected glioma
Externí odkaz:
https://doaj.org/article/64db032039ab42d2ae5a88c6325d8daf
Autor:
Matthew C. Garrett, Rebecca Albano, Troy Carnwath, Lubayna Elahi, Catherine Behrman, Merissa Pemberton, Daniel Woo, Eric O’Brien, Brett VanCauwenbergh, John Perentesis, Sanjit Shah, Matthew Hagan, Ady Kendler, Chuntao Zhao, Dave Plas, Aditi Paranjpe, Krishna Roskin, Harley Kornblum, Richard Lu
Introduction: Low-grade and secondary high-grade gliomas frequently contain a mutation in the IDH1 metabolic enzyme that is hypothesized to drive tumorigenesis by inhibiting many of the chromatin-regulating enzymes that regulate DNA structure. Much o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4be07286906ef6018637d53ed2e7b365
https://doi.org/10.21203/rs.3.rs-1720726/v1
https://doi.org/10.21203/rs.3.rs-1720726/v1
Autor:
Rebecca Albano, Krishna Roskin, Sanjit Shah, Michael Lamba, Aditi Paranjpe, Matthew Clark Garrett, Troy Carnwath, Richard Lu, Daniel Woo, Chuntao Zhao, David R. Plas
Introduction: The pathological changes in epigenetics and gene regulation that accompany the progression of low-grade to high-grade gliomas are under-studied. The authors use a large set of paired atac-seq and RNA-seq data from surgically resected gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b35b95ed343ecc77947720ab73c4e3
https://doi.org/10.21203/rs.3.rs-922269/v1
https://doi.org/10.21203/rs.3.rs-922269/v1
Autor:
Doug Lobner, Rebecca Albano
Publikováno v:
Neurotoxicity Research. 33:1-5
The study of the mechanism of β-N-methylamino-L-alanine (BMAA) neurotoxicity originally focused on its effects at the N-methyl-D-aspartate (NMDA) receptor. In recent years, it has become clear that its mechanism of action is more complicated. First,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20842d458f7dbe3ce4b9551b8a1851e7
https://doi.org/10.1007/s12640-017-9739-4
https://doi.org/10.1007/s12640-017-9739-4
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2015:1-9
The cystine/glutamate exchanger (systemxc-) mediates the transport of cystine into the cell in exchange for glutamate. By releasing glutamate, systemxc-can potentially cause excitotoxicity. However, through providing cystine to the cell, it regulates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a73946188f12e05cf518594ad53cf21
https://doi.org/10.1155/2015/269371
https://doi.org/10.1155/2015/269371
Autor:
Doug Lobner, Jon M. Resch, SuJean Choi, David A. Baker, Julie Hjelmhaug, XiaoQian Liu, Rebecca Albano
Publikováno v:
Synapse. 68:604-612
In the central nervous system, cystine import in exchange for glutamate through system xc- is critical for the production of the antioxidant glutathione by astrocytes, as well as the maintenance of extracellular glutamate. Therefore, regulation of sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d71d86bd516334b862bf937e0e6bf6b
https://doi.org/10.1002/syn.21772
https://doi.org/10.1002/syn.21772
Autor:
David A. Baker, Aric Madayag, John R. Mantsch, Rebecca Albano, SuJean Choi, Nicholas J Raddatz, Doug Lobner, Linghai Kong
Publikováno v:
Journal of neurochemistry. 137(3)
Glutamate signaling is achieved by an elaborate network involving neurons and astrocytes. Hence, it is critical to better understand how neurons and astrocytes interact to coordinate the cellular regulation of glutamate signaling. In these studies, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f7c4098f5eab96c03b10b52c2a83a1
https://pubmed.ncbi.nlm.nih.gov/26851652
https://pubmed.ncbi.nlm.nih.gov/26851652
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2015 (2015)
Oxidative Medicine and Cellular Longevity, Vol 2015 (2015)
The cystine/glutamate exchanger (system xc (-)) mediates the transport of cystine into the cell in exchange for glutamate. By releasing glutamate, system xc (-) can potentially cause excitotoxicity. However, through providing cystine to the cell, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a28108f0079d2c7f0b963e668151c497
https://pubmed.ncbi.nlm.nih.gov/25949770
https://pubmed.ncbi.nlm.nih.gov/25949770
Publikováno v:
Brain research. 1547
The cystine/glutamate antiporter (system xc-) transports cystine into cell in exchange for glutamate. Fibroblast growth factor-2 (FGF-2) upregulates system xc- selectively on astrocytes, which leads to increased cystine uptake, the substrate for glut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b56d522fb71e121cf1d6c69da2c0a89
https://pubmed.ncbi.nlm.nih.gov/24374066
https://pubmed.ncbi.nlm.nih.gov/24374066