Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Rebecca A. Rolfe"'
Autor:
Rebecca A. Rolfe, Ebru Talak Bastürkmen, Lauren Sliney, Grace Hayden, Nicholas Dunne, Niamh Buckley, Helen McCarthy, Spencer E. Szczesny, Paula Murphy
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
IntroductionFollowing early cell specification and tenocyte differentiation at the sites of future tendons, very little is known about how tendon maturation into robust load-bearing tissue is regulated. Between embryonic day (E)16 and E18 in the chic
Externí odkaz:
https://doaj.org/article/e81bb2067e9d46c1bc2b41ba8bf40b2e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
During embryonic development, tendons transform into a hypocellular tissue with robust tensile load-bearing capabilities. Previous work suggests that this mechanical transformation is due to increases in collagen fibril length and is dependent on mec
Externí odkaz:
https://doaj.org/article/259dedea1ebd423caa8de1c304b9baab
Publikováno v:
Genomics Data, Vol 2, Iss C, Pp 32-36 (2014)
Mechanical stimulation is important for the correct formation of the skeleton. Splotch-delayed mutant embryos (Pax3Spd/Spd) that develop with no limb muscle and therefore no limb movement experience an altered mechanical environment resulting in spec
Externí odkaz:
https://doaj.org/article/efe62b93d52846998e1ce9bbb1b54e9a
Publikováno v:
Cell and Tissue Research. 388:49-62
Publikováno v:
Frontiers in Cell and Developmental Biology
During embryonic development, tendons transform into a hypocellular tissue with robust tensile load-bearing capabilities. Previous work suggests that this mechanical transformation is due to increases in collagen fibril length and is dependent on mec
Publikováno v:
European cells & materials
European Cells & Materials, Vol 37, Pp 23-41 (2019)
European Cells & Materials, Vol 37, Pp 23-41 (2019)
Congenital spine deformities may be influenced by movements in utero, but the effects of foetal immobility on spine and rib development remain unclear. The purpose of the present study was to determine (1) critical time-periods when rigid paralysis c
Publikováno v:
Cell and tissue research. 388(1)
Spatial and temporal control of chondrogenesis generates precise, species-specific patterns of skeletal structures in the developing vertebrate limb. The pattern-template is laid down when mesenchymal cells at the core of the early limb bud condense
Publikováno v:
Developmental dynamics : an official publication of the American Association of AnatomistsREFERENCES. 250(3)
Background Abnormal fetal movements are implicated in joint pathologies such as arthrogryposis and developmental dysplasia of the hip (DDH). Experimentally induced paralysis disrupts joint cavitation and morphogenesis leading to postnatal abnormaliti
Autor:
Ahmed Z. Zaidon, Niamh C. Nowlan, Tyler Kim, James H. Bezer, Rebecca A. Rolfe, James C. Iatridis, Michelle L. Oyen
Publikováno v:
Journal of Orthopaedic Research. 35:2135-2144
The incidence of congenital spine deformities, including congenital scoliosis, kyphosis, and lordosis, may be influenced by the in utero mechanical environment, and particularly by fetal movements at critical time-points. There is a limited understan
Publikováno v:
Developmental dynamics : an official publication of the American Association of AnatomistsREFERENCES. 249(4)
Background Normal skeletal development, in particular ossification, joint formation and shape features of condyles, depends on appropriate mechanical input from embryonic movement but it is unknown how such physical stimuli are transduced to alter ge