Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Rebecca A. Haeusler"'
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 11, Pp 100278- (2022)
The small intestinal epithelium has classically been envisioned as a conduit for nutrient absorption, but appreciation is growing for a larger and more dynamic role for enterocytes in lipid metabolism. Considerable gaps remain in our knowledge of thi
Externí odkaz:
https://doaj.org/article/5c10cc5d6cf5482a86ceb180042612c6
Autor:
Wendy M. McKimpson, Taiyi Kuo, Takumi Kitamoto, Sei Higuchi, Jason C. Mills, Rebecca A. Haeusler, Domenico Accili
Publikováno v:
Gastro Hep Advances, Vol 1, Iss 5, Pp 733-745 (2022)
Background and Aims: Stomach cells can be converted to insulin-producing cells by Neurog3, MafA, and Pdx1 overexpression. Enteroendocrine cells can be similarly made to produce insulin by the deletion of FOXO1. Characteristics and functional properti
Externí odkaz:
https://doaj.org/article/2c7263fdf1894364af1e0072aae27e91
Autor:
María Concepción Izquierdo, Niroshan Shanmugarajah, Samuel X. Lee, Michael J. Kraakman, Marit Westerterp, Takumi Kitamoto, Michael Harris, Joshua R. Cook, Galina A. Gusarova, Kendra Zhong, Elijah Marbuary, InSug O-Sullivan, Nikolaus Rasmus, Stefania Camastra, Terry G. Unterman, Ele Ferrannini, Barry E. Hurwitz, Rebecca A. Haeusler
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 7 (2022)
Multiple beneficial cardiovascular effects of HDL depend on sphingosine-1-phosphate (S1P). S1P associates with HDL by binding to apolipoprotein M (ApoM). Insulin resistance is a major driver of dyslipidemia and cardiovascular risk. However, the mecha
Externí odkaz:
https://doaj.org/article/1bec1268dd814e7492b3638624ca8bed
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101326- (2021)
Objective: Murine-specific muricholic acids (MCAs) are reported to protect against obesity and associated metabolic disorders. However, the response of mice with genetic depletion of MCA to an obesogenic diet has not been evaluated. We used Cyp2c-def
Externí odkaz:
https://doaj.org/article/8cea1c68bffd436f89a84c983fb47341
Autor:
Fanny Langlet, Marcel Tarbier, Rebecca A. Haeusler, Stefania Camastra, Eleuterio Ferrannini, Marc R. Friedländer, Domenico Accili
Publikováno v:
Molecular Metabolism, Vol 17, Iss , Pp 49-60 (2018)
Objectives: Hepatic insulin resistance is a hallmark of type 2 diabetes and obesity. Insulin receptor signaling through AKT and FOXO has important metabolic effects that have traditionally been ascribed to regulation of gene expression. However, whet
Externí odkaz:
https://doaj.org/article/88dea607494c4d5a8f17c43347252fd5
Autor:
Rebecca A. Haeusler, Stefania Camastra, Brenno Astiarraga, Monica Nannipieri, Marco Anselmino, Ele Ferrannini
Publikováno v:
Molecular Metabolism, Vol 4, Iss 3, Pp 222-226 (2015)
Background/objectives: Increased endogenous glucose production is a hallmark of type 2 diabetes. Evidence from animal models has suggested that a likely cause of this is increased mRNA expression of glucose 6-phosphatase and phosphoenolpyruvate carbo
Externí odkaz:
https://doaj.org/article/49bb1311b7a143748574eab86c26361c
ObjectiveModulation of bile acid (BA) structure is a potential strategy for obesity and metabolic disease treatment. BAs act not only as signaling molecules involved in energy expenditure and glucose homeostasis, but also as regulators of food intake
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c880df5f40f74fd4ed37838f83dbacf
https://doi.org/10.1101/2022.12.01.518764
https://doi.org/10.1101/2022.12.01.518764
Autor:
Simone Bini, Laura D'Erasmo, Brenno Astiarraga, Ilenia Minicocci, Maria Palumbo, Valeria Pecce, Luca Polito, Alessia Di Costanzo, Rebecca A. Haeusler, Marcello Arca, Ele Ferrannini, Stefania Camastra
Publikováno v:
Nutr Metab Cardiovasc Dis
Introduction: Angiopoietin-like protein 3 (ANGPTL3) and 4 (ANGPTL4) are regulators of triglycerides storage and utilization. Bariatric surgery (BS) determines profound changes in adipose tissue composition and energy metabolism. We evaluated the impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718e6d4b1ba11baae7cfbf748eaf3375
https://europepmc.org/articles/PMC10018753/
https://europepmc.org/articles/PMC10018753/
Publikováno v:
Cellular and molecular gastroenterology and hepatology. 14(5)
Autor:
Ana B. Emiliano, Natalie R. Lopatinsky, Marko Kraljević, Sei Higuchi, Ying He, Rebecca A. Haeusler, Gary J. Schwartz
Publikováno v:
Am J Physiol Endocrinol Metab
Despite the high prevalence of obesity among middle-aged subjects, it is unclear if sex differences in middle age affect the metabolic outcomes of obesity therapies. Accordingly, in this study, middle-aged obese female and male mice were randomized t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e53b80a0a489fd2450ef5887d33443
https://europepmc.org/articles/PMC9273270/
https://europepmc.org/articles/PMC9273270/