Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rebecca A. Cowling"'
Autor:
Daniel P. Moore, George N. Nikopoulos, Stephen Bellum, Calvin P.H. Vary, Joseph M. Verdi, Stephen E. Kendall, Chris J. Kubu, Rebecca A. Cowling, Mahmud Bani-Yaghoub
Publikováno v:
Development. 131:4287-4298
Reports of non-neural differentiation of neural stem cells (NSCs) have been challenged by alternative explanations for expanded differentiation potentials. In an attempt to demonstrate the plasticity of NSC, neurospheres were generated from single re
Autor:
Joshua S. Himmelfarb, Joseph M. Verdi, Rebecca A. Cowling, Jennifer A. Rochira, Tamara L. Adams
Publikováno v:
Apoptosis : an international journal on programmed cell death. 15(1)
Bone morphogenetic signaling (BMP) is a key pathway during neurogenesis and depends on many downstream intermediators to carry out its signaling. One such signaling pathway utilizes neurotrophin receptor-interacting MAGE protein (NRAGE), a member of
Publikováno v:
Biochemistry. 29:6897-6903
Samples of purple lipoxygenase prepared by addition of either 13-hydroperoxy-9,11-octadecadienoic acid or linoleic acid and oxygen to ferric lipoxygenase contain pentadienyl and/or peroxyl radicals. The radicals are identified by the g values and hyp
Autor:
Stephen Bellum, Jennifer A. Rochira, George N. Nikopoulos, Joseph M. Verdi, Mahmud Bani-Yaghoub, Chris J. Kubu, Rebecca A. Cowling
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 236(3)
Loss of numb function suggests that numb maintains progenitors in an undifferentiated state. Herein, we demonstrate that numb1 and numb3 are expressed in undifferentiated cortical progenitors, whereas numb2 and numb4 become prominent throughout diffe
Autor:
Geoffrey N. Grove, Mark J. Nelson, Rebecca A. Cowling, Bridget A. Brennan, Chase Db, Robert C. Scarrow
Publikováno v:
Biochemistry. 34(46)
Ferric soybean lipoxygenase forms stable complexes with 4-substituted catechols. The structure of the complex between the enzyme and 3,4-dihydroxybenzonitrile has been studied by resonance Raman, electron paramagnetic resonance, visible, and X-ray sp
Autor:
Charles P. Buck, Mark J. Nelson, Milton G. Trimitsis, Rebecca A. Cowling, Geoffrey N. Grove, Robert C. Scarrow
Publikováno v:
Biochemistry. 33(50)
Iron K-edge X-ray spectroscopy (XANES and EXAFS) was used to study iron coordination in frozen solutions of soybean lipoxygenase-1 (SLO). The intensity of the 1s-->3d pre-edge transition of native iron(II) lipoxygenase is greater than what was found
Publikováno v:
Biochemistry. 33(16)
Soybean lipoxygenase isozyme 1 catalyzes the addition of dioxygen to fatty acid substrates that contain a 1,4-diene, generating allylic hydroperoxides. EPR spectra of purple enzyme solutions, formed by addition of saturating amounts of substrates or
Autor:
Rebecca A. Cowling, Mark J. Nelson
Publikováno v:
Journal of the American Chemical Society. 112:2820-2821
Publikováno v:
Archives of Biochemistry and Biophysics. 248:368-378
Dihydropyrimidine amidohydrolase (EC 3.5.2.2) catalyzes the reversible hydrolysis of 5,6-dihydropyrimidines to the corresponding β-ureido acids. Previous work has shown that incubation of this Zn2+ metalloenzyme with 2,6-dipicolinic acid, 8-hydroxyq
Autor:
Samuel T. Hess, Joshua S. Himmelfarb, Joseph M. Verdi, Rebecca A. Cowling, Jennifer A. Rochira
Publikováno v:
Biophysical Journal. (3):69a
Apoptosis, one form of programmed cell death, is used by tissues to develop normally and maintain homeostasis. Lack of apoptosis underlies many diseases such as cancer, while an excess can cause neurodegenerative disorders. Understanding the molecula