Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Rebecca A. Barnetson"'
Autor:
Albert Tenesa, Mark A. Jenkins, Laura Baglietto, Daniel D. Buchanan, Rebecca A. Barnetson, Yoland Antill, Jack Goldblatt, Encarna B. Gomez Garcia, Darren M. White, Malcolm G. Dunlop, Barbara A. Leggett, Annette H. J. T. Vriends, Jenny N. Poynter, Jeremy R. Jass, Robert W. Haile, Susan M. Farrington, Melyssa Aronson, Steve Gallinger, Finlay A. Macrae, Ingrid Winship, Heather Hampel, Stephen N. Thibodeau, Loic Le Marchand, Hans F. A. Vasen, Susan Parry, Michael Walsh, Albert de la Chapelle, Graeme Suthers, John A. Baron, Noralane M. Lindor, John D. Potter, Joanne P. Young, Nicola Cartwright, Anja Wagner, Graham G. Giles, James G. Dowty, Sven Arnold, John L. Hopper, Malinda L. Butz
Publikováno v:
Baglietto, L, Lindor, N M, Dowty, J G, White, D M, Wagner, A, Garcia, E B G, Vriends, A H J T, Cartwright, N R, Barnetson, R A, Farrington, S M, Tenesa, A, Hampel, H, Buchanan, D, Arnold, S, Young, J, Walsh, M D, Jass, J, Macrae, F, Antill, Y, Winship, I M, Giles, G G, Goldblatt, J, Parry, S, Suthers, G, Leggett, B, Butz, M, Aronson, M, Poynter, J N, Baron, J A, Le Marchand, L, Haile, R, Gallinger, S, Hopper, J L, Potter, J, de la Chapelle, A, Vasen, H F, Dunlop, M G & Thibodeau, S N & Jenkins, M A 2010, ' Risks of Lynch Syndrome Cancers for MSH6 Mutation Carriers ', JNCI: Journal of the National Cancer Institute, vol. 102, no. 3, pp. 193-201 . https://doi.org/10.1093/jnci/djp473
Journal of the National Cancer Institute, 102(3), 193-201. Oxford University Press
JNCI: Journal of the National Cancer Institute, 102(3), 193-201
Journal of the National Cancer Institute, 102(3), 193-201. Oxford University Press
JNCI: Journal of the National Cancer Institute, 102(3), 193-201
Background Germline mutations in MSH6 account for 10%-20% of Lynch syndrome colorectal cancers caused by hereditary DNA mismatch repair gene mutations. Because there have been only a few studies of mutation carriers, their cancer risks are uncertain.
Autor:
Rebecca A. Barnetson, Susan Shanley, J. Milliken, Margaret Schnitzler, C. Fung, J. Leary, Judy Kirk
Publikováno v:
Familial Cancer. 8:251-255
Immunohistochemistry of tumour samples is increasingly used in the triage of families where hereditary non-polyposis colorectal cancer (HNPCC) due to mismatch repair defects is suspected. Usually, this is undertaken in tumours that are a recognised p
Autor:
Sari Tuupanen, Melissa C. Southey, Ian Chandler, Enric Domingo, Paul D.P. Pharoah, Luis G. Carvajal-Carmona, D. Gareth Evans, Malcolm G. Dunlop, Trinidad Caldés, Graham G. Giles, Zoe Kemp, Harry Campbell, David J. Kerr, Alan M. Pittman, Eamonn R. Maher, D. Timothy Bishop, Jayaram Vijayakrishnan, Hans Morreau, Albert Tenesa, Asta Försti, Jean-Baptiste Cazier, Kimberley Howarth, Ella Barclay, Rebecca A. Barnetson, Tom van Wezel, Juul T. Wijnen, James G. D. Prendergast, Maggie Gorman, Julian Peto, Anneke Lucassen, Antoni Castells, Jochen Hampe, José A. G. Agúndez, Susan M. Farrington, Kate Sullivan, Henry Völzke, Richard Gray, Ulrich John, King Yip Cheng, Pavel Vodicka, Emma Jaeger, Peter Broderick, Judy W. C. Ho, Mobshra Qureshi, Lauri A. Aaltonen, Stephan Buch, Sarah Fielding, Sarah L. Spain, Lynn Martin, Andrew Rowan, Wendy Wood, Emily L. Webb, John M. Luk, Angel Carracedo, Clara Ruiz-Ponte, Alessio Naccarati, Steven J. Lubbe, Ian Tomlinson, Lara Lipton, John L. Hopper, Iina Niittymäki, Axel Walther, José M. Ladero, Pak C. Sham, Stefan Schreiber, Sergi Castellví-Bel, Miguel de la Hoya, Clemens Schafmayer, Gianluca Severi, Auli Karhu, Steven Penegar, Thibaud Koessler, Kari Hemminki, Richard S. Houlston, Huw Thomas
Publikováno v:
Nature Genetics. 40:623-630
To identify colorectal cancer (CRC) susceptibility alleles, we conducted a genome-wide association study. In phase 1, we genotyped 550,163 tagSNPs in 940 familial colorectal tumor cases (627 CRC, 313 high-risk adenoma) and 965 controls. In phase 2, w
Autor:
Annelot van Vliet, Mary Porteous, Susan M. Farrington, Jon Warner, Kate Drew, Rebecca A. Barnetson, Harry Campbell, Nicola Williams, Malcolm G. Dunlop, Nicola Cartwright, Naila Haq
Publikováno v:
Human Mutation. 29:367-374
Identification of germline mutations in DNA mismatch repair genes in colorectal cancer probands without an extensive family history can be problematic when ascribing relevance to cancer causation. We undertook a structured assessment of the disease-c
Autor:
Rebecca A. Barnetson, Harry Campbell, Albert Tenesa, Evropi Theodoratou, Susan M. Farrington, Roseanne Cetnarskyj, Mary Porteous, Geraldine McNeill, Malcolm G. Dunlop
Publikováno v:
American Journal of Epidemiology. 166:181-195
Fatty acid effects on colorectal cancer risk were examined in a national prospective case-control study in Scotland (1999-2006), including 1,455 incident cases and 1,455 matched controls. Three conditional logistic regression models adjusted for ener
Autor:
Rebecca A. Barnetson, Susan M. Farrington, Mary Porteous, Albert Tenesa, Malcolm G. Dunlop, Harry Campbell
Publikováno v:
British Journal of Cancer
Tenesa, A, Campbell, H, Barnetson, R, Porteous, M, Dunlop, M & Farrington, S M 2006, ' Association of MUTYH and colorectal cancer ', British Journal of Cancer, vol. 95, no. 2, pp. 239-242 . https://doi.org/10.1038/sj.bjc.6603239
Tenesa, A, Campbell, H, Barnetson, R, Porteous, M, Dunlop, M & Farrington, S M 2006, ' Association of MUTYH and colorectal cancer ', British Journal of Cancer, vol. 95, no. 2, pp. 239-242 . https://doi.org/10.1038/sj.bjc.6603239
Mutations in the MUTYH gene have been reported to be associated with increased risk of developing colorectal cancer. In this study, we confirmed this association using original data on 928 colorectal cancer cases and 845 healthy controls from Scotlan
Autor:
Rebecca A. Barnetson, Susan M. Farrington, Roseanne Cetnarskyj, Iain D. Nicholl, Mary Porteous, Harry Campbell, Albert Tenesa, Malcolm G. Dunlop
Publikováno v:
New England Journal of Medicine. 354:2751-2763
BACKGROUND The identification of mutations in germ-line DNA mismatch-repair genes at the time of diagnosis of colorectal cancer is important in the management of the disease. METHODS Without preselection and regardless of family history, we recruited
Autor:
David Duggan, Alan M. Pittman, Evi Theodoratou, Richard S. Houlston, Polly A. Newcomb, Graham Casey, Luis G. Carvajal-Carmona, John L. Hopper, Rebecca A. Barnetson, Mark A. Jenkins, David J. Kerr, Steven Gallinger, David V. Conti, Jean-Baptiste Cazier, Peter Broderick, James G. D. Prendergast, Ian Tomlinson, Malcolm G. Dunlop, Albert Tenesa, Kimberley Howarth, Sara E. Dobbins, Angela M. Jones, Harry Campbell, Susan M. Farrington
Publikováno v:
Human molecular genetics. 20(14)
We have previously identified several colorectal cancer (CRC)-associated polymorphisms using genome-wide association (GWA) analysis. We sought to fine-map the location of the functional variants for three of these regions at 8q23.3 (EIF3H), 16q22.1 (
Autor:
Bruno Buecher, Sean P. Cleary, Ignacio Blanco, Emily L. Webb, Lauri A. Aaltonen, Ian Tomlinson, S. Gallinger, Gabriel Capellá, Susa Enholm, E. M. Croitoru, Thibaud Koessler, Sébastien Küry, Mark A. Jenkins, Steven J. Lubbe, Kenneth Offit, Harry Campbell, Nathan A. Ellis, Annika Lindblom, Paul D.P. Pharoah, Albert Tenesa, Malcolm G. Dunlop, Aung Ko Win, Victor Moreno, Mary Porteous, Paolo Peterlongo, Stéphane Bézieau, Susan M. Farrington, Evropi Theodoratou, Rebecca A. Barnetson, Richard S. Houlston, Peter Broderick, Xiaoying Zhou
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
British Journal of Cancer
Recercat. Dipósit de la Recerca de Catalunya
instname
Theodoratou, E, Campbell, H, Tenesa, A, Houlston, R, Webb, E, Lubbe, S, Broderick, P, Gallinger, S, Croitoru, E M, Jenkins, M A, Win, A K, Cleary, S P, Koessler, T, Pharoah, P D, Kuery, S, Bezieau, S, Buecher, B, Ellis, N A, Peterlongo, P, Offit, K, Aaltonen, L A, Enholm, S, Lindblom, A, Zhou, X-L, Tomlinson, I P, Moreno, V, Blanco, I, Capella, G, Barnetson, R, Porteous, M E, Dunlop, M G & Farrington, S M 2010, ' A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants ', British Journal of Cancer, vol. 103, no. 12, pp. 1875-1884 . https://doi.org/10.1038/sj.bjc.6605966
Universidad de Barcelona
British Journal of Cancer
Recercat. Dipósit de la Recerca de Catalunya
instname
Theodoratou, E, Campbell, H, Tenesa, A, Houlston, R, Webb, E, Lubbe, S, Broderick, P, Gallinger, S, Croitoru, E M, Jenkins, M A, Win, A K, Cleary, S P, Koessler, T, Pharoah, P D, Kuery, S, Bezieau, S, Buecher, B, Ellis, N A, Peterlongo, P, Offit, K, Aaltonen, L A, Enholm, S, Lindblom, A, Zhou, X-L, Tomlinson, I P, Moreno, V, Blanco, I, Capella, G, Barnetson, R, Porteous, M E, Dunlop, M G & Farrington, S M 2010, ' A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants ', British Journal of Cancer, vol. 103, no. 12, pp. 1875-1884 . https://doi.org/10.1038/sj.bjc.6605966
BACKGROUND: Defective DNA repair has a causal role in hereditary colorectal cancer (CRC). Defects in the base excision repair gene MUTYH are responsible for MUTYH-associated polyposis and CRC predisposition as an autosomal recessive trait. Numerous r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50052520a414aa531567671f7f16b25
http://hdl.handle.net/2445/147246
http://hdl.handle.net/2445/147246
Autor:
Albert Tenesa, Rebecca A. Barnetson, Evropi Theodoratou, Harry Campbell, Farhat V N Din, Susan M. Farrington, Lesley A. Stark, Roseanne Cetnarskyj, Mary Porteous, Malcolm G. Dunlop
Publikováno v:
Gut. 59(12)
Background Previous studies have shown that aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) lower colorectal cancer (CRC) risk. However, the lowest effective NSAID dose, treatment duration, and effects on survival are not defined. In